3.4.22.67: zingipain

This is an abbreviated version!
For detailed information about zingipain, go to the full flat file.

Reaction

preferential cleavage of peptides with a proline residue at the P2 position =

Synonyms

Bgp, C01.017, cysteine proteinase GP-II, F50, ginger protease, ginger protease II, GP-II, zingibain

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.22 Cysteine endopeptidases

                3.4.22.67 zingipain

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Results	in table
6	Activating Compound
8	AA Sequence
3	Application
1	CAS Registry Number
2	Crystallization (Commentary)
4	General Information
3	General Stability
38	Inhibitors
2	KM Value [mM]
10	Metals/Ions
6	Molecular Weight [Da]
14	Organism
5	pH Optimum
4	pH Range
1	pH Stability
1	pI Value
2	Posttranslational Modification
8	Purification (Commentary)
1	Reaction
1	Reaction Type
14	Reference
9	Source Tissue
3	Specific Activity [micromol/min/mg]
3	Storage Stability
21	Substrates and Products (Substrate)
4	Subunits
13	Synonyms
4	Temperature Optimum [°C]
2	Temperature Range [°C]
3	Temperature Stability [°C]

Metals Ions

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Metals Ions on EC 3.4.22.67 - zingipain

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METALS and IONS

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

Ca2+

Zingiber officinale

-

activates

731939

Cu2+

Zingiber officinale

-

activates at 1-10 mM

731160

Fe2+

Zingiber officinale

-

activates at 1 mM, inhibits at 10 mM

731160

Hg2+

Zingiber officinale

-

activates at 1 mM, complete inhibition at 5-10 mM

731160

K+

Zingiber officinale

-

activates

731939

Mg2+

Zingiber officinale

-

activates at 1 mM, inhibits at 10 mM

731160

Mn2+

Zingiber officinale

-

activates at 1-10 mM

731160

Na+

Zingiber officinale

-

activates

731939

Zn2+

Zingiber officinale

-

activates at 1 mM, inhibits at 10 mM

731160

additional information

Zingiber officinale

-

the purified enzyme is highly stable against numerous metal ions

731939