3.4.21.106: hepsin
This is an abbreviated version!
For detailed information about hepsin, go to the full flat file.
Word Map on EC 3.4.21.106
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3.4.21.106
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prostate
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matriptase
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medicine
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hai-1
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prostasin
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trypsin-like
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ttsps
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pro-hgf
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amacr
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tmprss3
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uromodulin
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biotechnology
- 3.4.21.106
- prostate
- matriptase
- medicine
- hai-1
- prostasin
-
trypsin-like
-
ttsps
- pro-hgf
- amacr
-
tmprss3
-
uromodulin
- biotechnology
Reaction
cleavage after basic amino-acid residues, with Arg strongly preferred to Lys =
Synonyms
hepsin, S01.224, TMPRSS1, transmembrane serine protease 1, type II transmembrane serine protease
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 3.4.21.106 - hepsin
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REACTION DIAGRAM
hepatocyte growth factor precursor + H2O
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potential substrate for hepsin in vivo
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additional information
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hepsin reduces cell growth, cell invation and soft agar colony formation after expression in PC-3, LNCaP and DU145 cells
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