3.3.2.6: leukotriene-A4 hydrolase
This is an abbreviated version!
For detailed information about leukotriene-A4 hydrolase, go to the full flat file.
Word Map on EC 3.3.2.6
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3.3.2.6
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5-lipoxygenase
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arachidonic
-
epoxide
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medicine
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leukocyte
-
asthma
-
bestatin
-
chemoattractant
-
eicosanoids
-
metalloenzyme
-
flap
-
ionophore
-
alox5ap
-
tuberculous
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transcellular
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5-lipoxygenase-activating
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aminopeptidases
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captopril
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lipoxins
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pro-gly-pro
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montelukast
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proline-glycine-proline
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5-hete
-
zileuton
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diagnostics
-
pharmacology
-
drug development
- 3.3.2.6
-
5-lipoxygenase
-
arachidonic
- epoxide
- medicine
- leukocyte
- asthma
- bestatin
-
chemoattractant
-
eicosanoids
-
metalloenzyme
- flap
-
ionophore
-
alox5ap
-
tuberculous
-
transcellular
-
5-lipoxygenase-activating
- aminopeptidases
- captopril
-
lipoxins
- pro-gly-pro
- montelukast
- proline-glycine-proline
-
5-hete
- zileuton
- diagnostics
- pharmacology
- drug development
Reaction
Synonyms
EH, epoxide hydrolase, hydrolase, leukotriene A4, leukotriene A(4) hydrolase, leukotriene A4 hydrolase, leukotriene A4 hydrolase/aminopeptidase, leukotriene hydrolase A4, leukotriene-A4 hydrolase, leukotriene-A4-hydrolase, LT A4 hydrolase, LTA-4 hydrolase, LTA4 hydrolase, LTA4-h, LTA4H, More
ECTree
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KCat KM Value
KCat KM Value on EC 3.3.2.6 - leukotriene-A4 hydrolase
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1.497
L-alanine-7-amido-4-methylcoumarin
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in 250 mM Tris buffer, pH 7.5, containing 500 mM KCl and 0.1% (w/v) of bovine serum albumin, at 37°C
0.4706
L-arginine-7-amido-4-methylcoumarin
-
in 250 mM Tris buffer, pH 7.5, containing 500 mM KCl and 0.1% (w/v) of bovine serum albumin, at 37°C
0.343
L-leucine-7-amido-4-methylcoumarin
-
in 250 mM Tris buffer, pH 7.5, containing 500 mM KCl and 0.1% (w/v) of bovine serum albumin, at 37°C
0.617
L-lysine-7-amido-4-methylcoumarin
-
in 250 mM Tris buffer, pH 7.5, containing 500 mM KCl and 0.1% (w/v) of bovine serum albumin, at 37°C
0.298
L-methionine-7-amido-4-methylcoumarin
-
in 250 mM Tris buffer, pH 7.5, containing 500 mM KCl and 0.1% of bovine serum albumin, at 37°C
0.747
L-phenylalanine-7-amido-4-methylcoumarin
-
in 250 mM Tris buffer, pH 7.5, containing 500 mM KCl and 0.1% (w/v) of bovine serum albumin, at 37°C
0.449
L-proline-7-amido-4-methylcoumarin
-
in 250 mM Tris buffer, pH 7.5, containing 500 mM KCl and 0.1% (w/v) of bovine serum albumin, at 37°C
0.002
-
mutant N362L, 25°C, pH not specified in the publication
0.005
L-alanine 2-naphthylamide
-
mutant N362E, 25°C, pH not specified in the publication
0.01
L-alanine 2-naphthylamide
-
wild-type, 25°C, pH not specified in the publication
0.032
L-alanine 2-naphthylamide
-
mutant N362Q, 25°C, pH not specified in the publication
0.073
L-alanine 2-naphthylamide
-
mutant D399A, 25°C, pH not specified in the publication
0.321
L-alanine 2-naphthylamide
-
mutant W365L, 25°C, pH not specified in the publication
0.001
-
mutant N362L, 25°C, pH not specified in the publication
0.009
L-arginine 2-naphthylamide
-
mutant N362E, 25°C, pH not specified in the publication
0.04
L-arginine 2-naphthylamide
-
wild-type, 25°C, pH not specified in the publication
0.09
L-arginine 2-naphthylamide
-
mutant N362Q, 25°C, pH not specified in the publication
0.117
L-arginine 2-naphthylamide
-
mutant D399A, 25°C, pH not specified in the publication
0.141
L-arginine 2-naphthylamide
-
mutant W365L, 25°C, pH not specified in the publication
0.012
-
mutant N362Q, 25°C, pH not specified in the publication
0.026
L-isoleucine 2-naphthylamide
-
mutant D399A, 25°C, pH not specified in the publication
0.03
L-isoleucine 2-naphthylamide
-
wild-type, 25°C, pH not specified in the publication
0.055
L-isoleucine 2-naphthylamide
-
mutant W365L, 25°C, pH not specified in the publication
0.005
-
mutant N362L, 25°C, pH not specified in the publication
0.018
L-leucine 2-naphthylamide
-
mutant N362E, 25°C, pH not specified in the publication
0.057
L-leucine 2-naphthylamide
-
mutant N362Q, 25°C, pH not specified in the publication
0.2
L-leucine 2-naphthylamide
-
wild-type, 25°C, pH not specified in the publication
0.238
L-leucine 2-naphthylamide
-
mutant D399A, 25°C, pH not specified in the publication
0.292
L-leucine 2-naphthylamide
-
mutant W365L, 25°C, pH not specified in the publication
0.025
-
mutant N362L, 25°C, pH not specified in the publication
0.052
L-methionine 2-naphthylamide
-
mutant N362E, 25°C, pH not specified in the publication
0.177
L-methionine 2-naphthylamide
-
mutant N362Q, 25°C, pH not specified in the publication
0.21
L-methionine 2-naphthylamide
-
wild-type, 25°C, pH not specified in the publication
0.263
L-methionine 2-naphthylamide
-
mutant D399A, 25°C, pH not specified in the publication
0.453
L-methionine 2-naphthylamide
-
mutant W365L, 25°C, pH not specified in the publication
0.016
-
mutant N362Q, 25°C, pH not specified in the publication
0.03
L-valine 2-naphthylamide
-
mutant D399A, 25°C, pH not specified in the publication
0.042
L-valine 2-naphthylamide
-
mutant W365L, 25°C, pH not specified in the publication
0.05
L-valine 2-naphthylamide
-
wild-type, 25°C, pH not specified in the publication