3.2.2.19: [protein ADP-ribosylarginine] hydrolase

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For detailed information about [protein ADP-ribosylarginine] hydrolase, go to the full flat file.

Word Map on EC 3.2.2.19

3.2.2.19

adp-ribosylation

nad:arginine

polyadp-ribose

mono-adp-ribosylation

pargs

arginine-specific

adp-ribose-arginine

macrodomains

nsp3

monoadp-ribosylated

mono-adp-ribosyltransferase

Reaction

Synonyms

AAH, ADP-ribose-L-arginine cleavage enzyme, ADP-ribose-L-arginine cleaving enzyme, ADP-ribosyl(arginine)protein hydrolase, ADP-ribosyl-acceptor hydrolase, ADP-ribosylarginine glycohydrolase, ADP-ribosylarginine hydrolase, ADP-ribosylhydrolase, ADP-ribosylhydrolase 1, ADP-ribosylhydrolase 3, ADP-ribosylhydrolase-like 1, ADPRH, AdprHl1, ARH1, ARH3, hARH1, mono-ADP-ribosyl-arginine hydrolase, More, Nomega-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase, O-acetyl-ADP-ribose hydrolase, PARG, poly(ADP-ribose) glycohydrolase, poly-(ADP-ribose) glycohydrolase, [protein ADP-ribosylarginine] hydrolase

ECTree

3 Hydrolases

3.2 Glycosylases

3.2.2 Hydrolysing N-glycosyl compounds

3.2.2.19 [protein ADP-ribosylarginine] hydrolase

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Results	in table
17	Activating Compound
69	AA Sequence
1	CAS Registry Number
19	Cloned(Commentary)
3	Crystallization (Commentary)
46	Disease/ Diagnostics
3	General Information
2	IC50 Value
40	Inhibitors
1	Ki Value [mM]
6	KM Value [mM]
4	Localization
29	Metals/Ions
28	Molecular Weight [Da]
26	Natural Substrates/ Products (Substrates)
61	Organism
4	PDB ID
2	pH Optimum
5	Protein Variants
29	Purification (Commentary)
2	Reaction
4	Reaction Type
61	Reference
65	Source Tissue
16	Specific Activity [micromol/min/mg]
52	Substrates and Products (Substrate)
4	Subunits
32	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Specific Activity

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Specific Activity on EC 3.2.2.19 - [protein ADP-ribosylarginine] hydrolase

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0.0000395

thiol-sensitive form

0.0000476

0.0000487

thiol-resistant form

0.00008

partially purified from kidney

0.00009

0.00016

0.00045

partially purified from spleen

137041

0.00046

Rattus norvegicus

partially purified from testis

137041

0.00049

Rattus norvegicus

partially purified from brain

137041

0.00183

Rattus norvegicus

as a GST-fusion protein in cerebrospinal fluid

137046

0.00815

Rattus norvegicus

as a GST-fusion protein in brain cytosol

137046

0.32

Rattus norvegicus

as a GST-fusion protein

137045

0.55

Rattus norvegicus

as a GST-fusion protein

137048

3.15

Rattus norvegicus

after 20000fold purification

137041