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3.2.1.76: L-iduronidase

This is an abbreviated version!
For detailed information about L-iduronidase, go to the full flat file.

Word Map on EC 3.2.1.76

Reaction

O-(alpha-L-iduronic acid)-(1-4)-D-O-(alpha glucosamine 6-sulfate)-(1-4)-L-O-(alpha-L-iduronic acid)-D-O-2,5-anhydro-mannitol 6-sulfate
+
H2O
=
D-O-(alpha glucosamine 6-sulfate)-(1-4)-L-O-(alpha-L-iduronic acid)-D-O-2,5-anhydro-mannitol 6-sulfate
+
alpha-L-iduronic acid

Synonyms

Aldurazyme, alpha-IDUA, alpha-iduronidase, alpha-L-iduronidase, alpha-L-iduronidase A, glycosaminoglycan alpha-L-iduronohydrolase, hIDUA, IDU, IDUA, iduronidase, laronidase, More, rIDUA_RLT

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
                3.2.1.76 L-iduronidase

Sequence

Sequence on EC 3.2.1.76 - L-iduronidase

Please use the AA Sequence and Transmembrane Helices Search for a specific query.
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
IDUA_CANLF
655
0
72939
Swiss-Prot
Secretory Pathway (Reliability: 2)
IDUA_HUMAN
653
0
72670
Swiss-Prot
Secretory Pathway (Reliability: 2)
IDUA_MOUSE
634
0
71254
Swiss-Prot
Secretory Pathway (Reliability: 2)
A0A7W6FH89_9HYPH
621
0
68569
TrEMBL
-
B7PH31_IXOSC
434
0
48094
TrEMBL
Mitochondrion (Reliability: 5)
A0A7W5KHZ0_9HYPH
619
0
68698
TrEMBL
-
A0A7W7E1Z5_RHILE
620
0
68709
TrEMBL
-
Q6DCS7_XENLA
630
0
72116
TrEMBL
Secretory Pathway (Reliability: 1)
A0A097HWG4_FELCA
643
0
71817
TrEMBL
Secretory Pathway (Reliability: 1)
A0A812AVH6_SEPPH
622
0
71818
TrEMBL
Mitochondrion (Reliability: 5)
J9QQV7_HUMAN
64
0
7328
TrEMBL
other Location (Reliability: 3)
A0A7W6RRU4_9HYPH
624
0
69347
TrEMBL
-
A0A6P0DBY0_RHILE
621
0
68788
TrEMBL
-
A0A7W6UH37_9HYPH
621
0
68662
TrEMBL
-
Q6BE00_XENLA
484
1
53958
TrEMBL
Secretory Pathway (Reliability: 3)
A0A427N751_9HYPH
621
0
68598
TrEMBL
-
A0A7W6QAA4_9HYPH
620
0
68846
TrEMBL
-
A0A6J8CVS9_MYTCO
615
0
70623
TrEMBL
other Location (Reliability: 4)
A0A7W5T4T6_9HYPH
623
0
69021
TrEMBL
-
A0A7W6ZIN3_RHIET
626
0
69504
TrEMBL
-
A0A7W5LNS4_9HYPH
597
0
66137
TrEMBL
-
Q5QSL1_XENTR
484
1
53937
TrEMBL
Secretory Pathway (Reliability: 4)
A0A7W5VKN4_9HYPH
621
0
68428
TrEMBL
-
Q7SX76_DANRE
483
1
53937
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1S9G9G9_9HYPH
621
0
68934
TrEMBL
-