3.1.16.1: spleen exonuclease

This is an abbreviated version!
For detailed information about spleen exonuclease, go to the full flat file.

Word Map on EC 3.1.16.1

3.1.16.1

flap

endonuclease-1

structure-specific

okazaki

nucleases

micrococcal

snake

polynucleotide

5'-flaps

32p-postlabeling

3'-monophosphate

long-patch

lagging-strand

2'-deoxyguanosine

5'-exonuclease

exonucleolytic

dinucleoside

fen1

analysis

internucleotide

Reaction

exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 3'-phosphates =

Synonyms

3'-5' exonuclease, 3'-exonuclease, 3'-nucleotide phosphodiesterase, 5' -> 3' exonuclease Xrn2, 5' 3'-exonuclease, 5'-to-3' exonuclease, 5->3 exoribonuclease, Ape2, beef spleen exonuclease, BSEase, BSP, EC 3.1.4.18, exonuclease, FEN-1, flap endonuclease-1, More, NPP1, nucleotide pyrophosphatase/phosphodiesterase 1, phosphodiesterase II, spleen phosphodiesterase, Trm2p, XRNA, XRNB, XRNC, XRND

ECTree

3 Hydrolases

3.1 Acting on ester bonds

3.1.16 Exonucleases that are active with either ribo- or deoxyribonucleic acids and produce 3'-phosphomonoesters

3.1.16.1 spleen exonuclease

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Results	in table
2	Activating Compound
39	AA Sequence
12	Application
1	CAS Registry Number
6	Cloned(Commentary)
47	Disease/ Diagnostics
14	IC50 Value
44	Inhibitors
1	Ki Value [mM]
12	KM Value [mM]
11	Localization
8	Metals/Ions
12	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
38	Organism
11	pH Optimum
4	pH Range
1	pH Stability
2	Posttranslational Modification
4	Protein Variants
17	Purification (Commentary)
2	Reaction
1	Reaction Type
38	Reference
26	Source Tissue
12	Specific Activity [micromol/min/mg]
3	Storage Stability
74	Substrates and Products (Substrate)
2	Subunits
40	Synonyms
3	Temperature Optimum [°C]
7	Temperature Stability [°C]
3	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 3.1.16.1 - spleen exonuclease

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polynucleotides + H2O

3'-phosphomononucleotides

3 entries

polynucleotides + H2O

phosphomononucleotides

Homo sapiens

the enzyme contributes to the turnover of messenger RNAs in eukaryotic cells

666249

additional information

Sulfurisphaera tokodaii

NurA may function closely together with SSB in DNA transactions in archaea

690712