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3.1.16.1: spleen exonuclease

This is an abbreviated version!
For detailed information about spleen exonuclease, go to the full flat file.

Word Map on EC 3.1.16.1

Reaction

exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 3'-phosphates =

Synonyms

3'-5' exonuclease, 3'-exonuclease, 3'-nucleotide phosphodiesterase, 5' -> 3' exonuclease Xrn2, 5' 3'-exonuclease, 5'-to-3' exonuclease, 5->3 exoribonuclease, Ape2, beef spleen exonuclease, BSEase, BSP, EC 3.1.4.18, exonuclease, FEN-1, flap endonuclease-1, More, NPP1, nucleotide pyrophosphatase/phosphodiesterase 1, phosphodiesterase II, spleen phosphodiesterase, Trm2p, XRNA, XRNB, XRNC, XRND

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.16 Exonucleases that are active with either ribo- or deoxyribonucleic acids and produce 3'-phosphomonoesters
                3.1.16.1 spleen exonuclease

Temperature Stability

Temperature Stability on EC 3.1.16.1 - spleen exonuclease

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
35 - 60
-
incubation at pH 5.7, 10 min: 90% of initial activity at 35°C, 10% at 60°C
45 - 80
-
range of thermal inactivation, 50% of activity at 56°C
61
-
lost of 50% of activity after heating of partially purified enzyme for 5 min
64
-
lost of 50% of activity after heating of partially purified enzyme for 5 min