1.1.1.91: aryl-alcohol dehydrogenase (NADP+)

This is an abbreviated version, for detailed information about aryl-alcohol dehydrogenase (NADP+), go to the full flat file.

Reaction

An aromatic alcohol
+
NADP+
=
an aromatic aldehyde
+
NADPH
+
H+

Synonyms

AAD, Aad1p, ADH, aryl alcohol dehydrogenase (nicotinamide adenine dinucleotide phosphate) coniferyl alcohol dehydrogenase, aryl-alcohol dehydrogenase, NADPH-linked benzaldehyde reductase, SDR A5, SDR B3, short-chain dehydrogenase/reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.91 aryl-alcohol dehydrogenase (NADP+)

Substrates Products

Substrates Products on EC 1.1.1.91 - aryl-alcohol dehydrogenase (NADP+)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(E)-oct-2-enal + NADPH + H+
trans-2-octen-1-ol + NADP+
show the reaction diagram
-
-
-
?
(R)-1-phenylethanol + NAD+
1-phenylacetaldehyde + NADH + H+
show the reaction diagram
(R)-2-octanol + NADPH + H+
?
show the reaction diagram
(S)-1-phenylethanol + NADP+
1-phenylacetaldehyde + NADPH + H+
show the reaction diagram
(S)-2-octanol + NADPH + H+
?
show the reaction diagram
1-butanol + NADP+
butyraldehyde + NADPH + H+
show the reaction diagram
56% activity compared to crotyl alcohol
-
-
?
1-propanol + NADP+
propionaldehyde + NADPH + H+
show the reaction diagram
17.4% activity compared to crotyl alcohol
-
-
?
2,4-dimethoxybenzyl alcohol + NADP+
2,4-dimethoxybenzyl aldehyde + NADPH + H+
show the reaction diagram
-
-
-
?
2-fluorobenzaldehyde + NADPH
2-fluorobenzyl alcohol + NADP+
show the reaction diagram
-
relative activity: 27% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
2-hydroxyacetophenone + NADPH + H+
(S)-1,2-phenylethanediol + NADP+
show the reaction diagram
-
-
-
?
2-methoxybenzaldehyde + NADPH
2-methoxybenzyl alcohol + NADP+
show the reaction diagram
-
relative activity: 58% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
2-methyl-propanol + NADPH + H+
?
show the reaction diagram
2-nitrobenzaldehyde + NADPH
2-nitrobenzyl alcohol + NADP+
show the reaction diagram
-
relative activity: 57% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
3,4,5-trimethoxybenzaldehyde + NADPH
3,4,5-trimethoxybenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
?
3,4-dihydroxybenzaldehyde + NADPH
3,4-dihydroxybenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
?
3,4-dimethoxybenzaldehyde + NADH
3,4-dimethoxybenzyl alcohol + NAD+
show the reaction diagram
-
-
-
-
r
3,4-dimethoxybenzaldehyde + NADPH
3,4-dimethoxybenzyl alcohol + NADP+
show the reaction diagram
3,4-dimethoxybenzyl alcohol + NADP+
?
show the reaction diagram
-
-
-
?
3,4-dimethoxybenzyl alcohol + NADP+
veratraldehyde + NADPH + H+
show the reaction diagram
-
-
-
r
3,5-dimethoxybenzaldehyde + NADPH
3,5-dimethoxybenzyl alcohol + NADP+
show the reaction diagram
3-chlorobenzaldehyde + NADPH
3-chlorobenzyl alcohol + NADP+
show the reaction diagram
-
relative activity: 73% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
3-fluorobenzaldehyde + NADPH
3-fluorobenzyl alcohol + NADP+
show the reaction diagram
-
relative activity: 69% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
3-hydroxy-4-methoxy-benzaldehyde + NADPH
3-hydroxy-4-methoxy-benzyl alcohol + NADP+
show the reaction diagram
-
relative activity: 17% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
3-hydroxy-4-methoxybenzaldehyde + NADPH + H+
3-hydroxy-4-methoxybenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
?
3-methoxybenzaldehyde + NADPH
3-methoxybenzyl alcohol + NADP+
show the reaction diagram
-
relative activity: 117% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
3-methyl-butanol + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
3-nitrobenzaldehyde + NADPH
3-nitrobenzyl alcohol + NADP+
show the reaction diagram
-
relative activity: 25% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
4-(hydroxymethyl)benzoic acid + NAD+
? + NADH + H+
show the reaction diagram
-
-
-
?
4-benzyloxy-3-methoxybenzaldehyde + NADPH + H+
4-benzyloxy-3-methoxybenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
?
4-chlorobenzaldehyde + NADPH
4-chlorobenzyl alcohol + NADP+
show the reaction diagram
-
relative activity: 61% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
4-fluorobenzaldehyde + NADPH
4-fluorobenzyl alcohol + NADP+
show the reaction diagram
-
relative activity: 29% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
4-hydroxy-3-methoxy-benzaldehyde + NADPH
4-hydroxy-3-methoxy-benzyl alcohol + NADP+
show the reaction diagram
-
relative activity: 19% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
4-hydroxy-3-methoxybenzaldehyde + NADPH + H+
4-hydroxy-3-methoxybenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
?
4-hydroxybenzaldehyde + NADPH
4-hydroxybenzyl alcohol + NADP+
show the reaction diagram
-
relative activity: 34% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
4-hydroxybenzaldehyde + NADPH + H+
4-hydroxybenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
?
4-methoxybenzaldehyde + NADPH
4-methoxybenzyl alcohol + NADP+
show the reaction diagram
-
relative activity: 110% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
4-methoxybenzaldehyde + NADPH + H+
4-methoxybenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
?
4-methoxybenzyl alcohol + NADP+
4-methoxybenzaldehyde + NADPH
show the reaction diagram
4-nitrobenzaldehyde + NADPH
4-nitrobenzyl alcohol + NADP+
show the reaction diagram
-
relative activity: 31% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
5-(hydroxymethyl)-2-furaldehyde + NADPH + H+
(furan-2,5-diyl)dimethanol + NADP+
show the reaction diagram
-
relative activity: 36% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
acetaldehyde + NADPH + H+
ethanol + NADP+
show the reaction diagram
-
-
-
-
r
acetophenone + NADPH + H+
?
show the reaction diagram
-
-
-
r
alpha-ionone + NADPH + H+
?
show the reaction diagram
-
-
-
r
benzaldehyde + NADPH
benzyl alcohol + NADP+
show the reaction diagram
benzaldehyde + NADPH + H+
benzyl alcohol + NAD+
show the reaction diagram
reduction of benzaldehyde at pH 6.0 is NADPH-dependent while NADH does not yield detectable activity under the same conditions
-
-
r
benzaldehyde + NADPH + H+
benzyl alcohol + NADP+
show the reaction diagram
highest reductive activity with benzaldehyde
-
-
r
benzil + NADPH + H+
benzoin + NADP+
show the reaction diagram
-
-
-
-
?
benzyl alcohol + NAD+
benzaldehyde + NADPH + H+
show the reaction diagram
oxidation of benzyl alcohol at pH 9.6 is NAD+-dependent while NADP+ did not yield detectable activity under the same conditions
-
-
r
benzyl alcohol + NADP+
benzaldehyde + NADPH
show the reaction diagram
benzyl alcohol + NADP+
benzaldehyde + NADPH + H+
show the reaction diagram
butanol + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
cinnamic alcohol + NADP+
cinnamic aldehyde + NADPH
show the reaction diagram
coniferyl alcohol + NADP+
coniferylaldehyde + NADPH + H+
show the reaction diagram
crotonaldehyde + NADPH + H+
crotonyl alcohol + NADP+
show the reaction diagram
-
-
-
r
crotonyl alcohol + NADP+
crotonaldehyde + NADPH + H+
show the reaction diagram
highest oxidative activity with crotyl alcohol
-
-
r
decanal + NADPH
decanol + NADP+
show the reaction diagram
-
relative activity: 2% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
heptaldehyde + NADPH
?
show the reaction diagram
-
relative activity: 26% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
hexanal + NADPH
hexanol + NADP+
show the reaction diagram
-
relative activity: 47% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
m-bromobenzaldehyde + NADPH + H+
m-bromobenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
r
m-chlorobenzaldehyde + NADPH + H+
m-chlorobenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
r
m-fluorobenzaldehyde + NADPH + H+
m-fluorobenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
r
m-hydroxybenzaldehyde + NADPH + H+
m-hydroxybenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
r
m-nitrobenzaldehyde + NADPH
m-nitrobenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
r
n-butanol + NADP+
n-butanal + NADPH
show the reaction diagram
-
-
-
-
r
n-pentanol + NADP+
n-pentanal + NADPH
show the reaction diagram
-
-
-
-
r
n-propanol + NADP+
n-propanal + NADPH
show the reaction diagram
-
-
-
-
r
nonanal + NADPH
nonanol + NADP+
show the reaction diagram
-
relative activity: 3% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
o-bromobenzaldehyde + NADPH + H+
o-bromobenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
r
o-chlorobenzaldehyde + NADPH + H+
o-chlorobenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
r
o-fluorobenzaldehyde + NADPH + H+
o-fluorobenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
r
octanal + NADPH
octanol + NADP+
show the reaction diagram
-
relative activity: 37% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
p-aminobenzyl alcohol + NADP+
p-aminobenzaldehyd + NADPH
show the reaction diagram
-
-
-
-
r
p-bromobenzaldehyde + NADPH + H+
p-bromobenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
r
p-chlorobenzaldehyde + NADPH + H+
p-chlorobenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
r
p-fluorobenzaldehyde + NADPH + H+
p-fluorobenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
r
p-hydroxybenzaldehyde + NADPH + H+
p-hydroxybenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
r
p-methylbenzaldehyde + NADPH
p-methylbenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
r
pentanal + NADPH
pentanol + NADP+
show the reaction diagram
-
relative activity: 8% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
phenylacetaldehyde + NADPH
phenylethanol + NADP+
show the reaction diagram
-
relative activity: 109 (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
phenylacetaldehyde + NADPH + H+
phenylethanol + NADP+
show the reaction diagram
-
-
-
-
?
rac-4-methyl-2-pentanol + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
rac-butan-2,3-diol + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
salicyl alcohol + NADP+
p-hydroxybenzaldehyde + NADPH
show the reaction diagram
-
i.e. p-hydroxybenzyl alcohol
-
-
r
trans-4-phenyl-3-buten-2-one + NADPH + H+
?
show the reaction diagram
-
-
-
r
trans-cinnamaldehyde + NADPH
?
show the reaction diagram
-
relative activity: 39% (reference substrate: 3,4-dimethoxybenzaldehyde)
-
-
r
vanillin + NADPH + H+
vanillic alcohol + NADP+
show the reaction diagram
-
-
-
r
veratraldehyde + NADPH + H+
3,4-dimethoxybenzyl alcohol + NADP+
show the reaction diagram
-
-
-
r
veratryl alcohol + NADP+
veratraldehyde + NADPH
show the reaction diagram
-
i.e. 3,4-dimethoxybenzyl alcohol
-
-
r
additional information
?
-