1.1.1.91: aryl-alcohol dehydrogenase (NADP+)

This is an abbreviated version, for detailed information about aryl-alcohol dehydrogenase (NADP+), go to the full flat file.

Reaction

An aromatic alcohol
+
NADP+
=
an aromatic aldehyde
+
NADPH
+
H+

Synonyms

AAD, Aad1p, ADH, aryl alcohol dehydrogenase (nicotinamide adenine dinucleotide phosphate) coniferyl alcohol dehydrogenase, aryl-alcohol dehydrogenase, NADPH-linked benzaldehyde reductase, SDR A5, SDR B3, short-chain dehydrogenase/reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.91 aryl-alcohol dehydrogenase (NADP+)

KM Value

KM Value on EC 1.1.1.91 - aryl-alcohol dehydrogenase (NADP+)

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
5.5
(R)-1-phenylethanol
wild-type, pH 8.3, 30C
1.2 - 17.6
(S)-1-phenylethanol
7.1 - 7.7
(S)-2-octanol
0.012
3,4-dimethoxybenzaldehyde
-
pH 6.1, 30C
0.37
3,4-dimethoxybenzyl alcohol
-
pH 6.1, 30C
0.022
3,5-dimethoxybenzaldehyde
-
pH 6.1, 30C
1.4
3-hydroxy-4-methoxy-benzaldehyde
-
pH 6.1, 30C
0.55
3-phenylpropionaldehyde
-
-
1.4
4-Hydroxy-3-methoxy-benzaldehyde
-
pH 6.1, 30C
25
4-hydroxy-3-methoxy-benzyl alcohol
-
pH 6.1, 30C
0.09 - 0.5
4-methoxybenzaldehyde
1.7
4-methoxybenzyl alcohol
-
-
0.27
5-(hydroxymethyl)-2-furaldehyde
-
pH 6.1, 30C
1.7
acetaldehyde
-
-
0.34 - 1.7
benzaldehyde
0.057 - 14
benzyl alcohol
0.22
cinnamic aldehyde
-
-
0.55
coniferyl alcohol
-
-
0.14
coniferyl aldehyde
-
-
3.3
crotonaldehyde
at pH 8.0 and 55C
9.1
crotonyl alcohol
at pH 8.0 and 55C
0.16
m-bromobenzaldehyde
-
-
0.1
m-chlorobenzaldehyde
-
-
0.42
m-fluorobenzaldehyde
-
-
1.1
m-hydroxybenzaldehyde
-
-
0.21
m-nitrobenzaldehyde
-
-
0.8 - 3.1
NAD+
0.0026 - 0.22
NADH
0.024 - 2.3
NADP+
0.017 - 0.1
NADPH
0.25
o-bromobenzaldehyde
-
-
0.2
o-chlorobenzaldehyde
-
-
0.27
o-fluorobenzaldehyde
-
-
0.05
o-nitrobenzaldehyde
-
-
0.04
p-aminobenzyl alcohol
-
-
0.22
p-bromobenzaldehyde
-
-
0.34
p-chlorobenzaldehyde
-
-
0.26
p-fluorobenzaldehyde
-
-
0.09
p-Hydroxybenzaldehyde
-
-
0.3
p-methylbenzaldehyde
-
-
0.04
p-nitrobenzaldehyde
-
-
0.53
phenylacetaldehyde
-
pH 6.1, 30C
3.4
trans-cinnamaldehyde
-
pH 6.1, 30C
0.25
veratraldehyde
at pH 6.0 temperature not specified in the publication