1.1.1.61: 4-hydroxybutyrate dehydrogenase

This is an abbreviated version, for detailed information about 4-hydroxybutyrate dehydrogenase, go to the full flat file.

Reaction

4-hydroxybutanoate
+
NAD+
=
succinate semialdehyde
+
NADH
+
H+

Synonyms

4HBD, gamma-hydroxybutyrate dehydrogenase, GHBDH, PGN 0724 protein, succinate semialdehyde reductase, uncharacterized oxidoreductase YihU, yihU

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.61 4-hydroxybutyrate dehydrogenase

Cloned

Cloned on EC 1.1.1.61 - 4-hydroxybutyrate dehydrogenase

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Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
complementation experiments with a succinic semialdehyde dehydrogenase deficient yeast strain uga2, complemented yeast is able to use gamma-aminobutyrate as nitrogen source
expressed as a histidine-tagged recombinant protein in Escherichia coli
expressed in Escherichia coli BL21 cells
-
expressed in Escherichia coli pLysS as stable fusion protein
-