1.1.1.61: 4-hydroxybutyrate dehydrogenase

This is an abbreviated version, for detailed information about 4-hydroxybutyrate dehydrogenase, go to the full flat file.

Reaction

4-hydroxybutanoate
+
NAD+
=
succinate semialdehyde
+
NADH
+
H+

Synonyms

4HBD, gamma-hydroxybutyrate dehydrogenase, GHBDH, PGN 0724 protein, succinate semialdehyde reductase, uncharacterized oxidoreductase YihU, yihU

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.61 4-hydroxybutyrate dehydrogenase

Substrates Products

Substrates Products on EC 1.1.1.61 - 4-hydroxybutyrate dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
3-hydroxypropane sulfonate + NAD+
? + NADH
show the reaction diagram
3-hydroxypropane sulfonate + NAD+
? + NADH + H+
show the reaction diagram
-
-
-
r
4-hydroxybutanoate + NAD+
succinate semialdehyde + NADH + H+
show the reaction diagram
-
-
-
-
r
4-hydroxybutanoate + NADP+
succinate semialdehyde + NADPH + H+
show the reaction diagram
-
-
-
-
?
ethanol + NADP+
ethanal + NADPH + H+
show the reaction diagram
-
-
-
-
?
gamma-hydroxybutyrate + NAD+
succinic semialdehyde + NADH + H+
show the reaction diagram
-
-
-
r
methylglyoxal + NAD+
? + NADH
show the reaction diagram
methylglyoxal + NAD+
? + NADH + H+
show the reaction diagram
-
-
-
r
succinate semialdehyde + NAD(P)H + H+
4-hydroxybutanoate + NAD(P)+
show the reaction diagram
succinate semialdehyde + NADH + H+
4-hydroxybutanoate + NAD+
show the reaction diagram
succinate semialdehyde + NADPH + H+
4-hydroxybutanoate + NADP+
show the reaction diagram
succinic semialdehyde + NADH + H+
4-hydroxybutyrate + NAD+
show the reaction diagram
succinic semialdehyde + NADH + H+
gamma-hydroxybutyrate + NAD+
show the reaction diagram
succinic semialdehyde is the preferred substrate
-
-
r
additional information
?
-