1.1.1.23: histidinol dehydrogenase

This is an abbreviated version, for detailed information about histidinol dehydrogenase, go to the full flat file.

Reaction

L-Histidinol
+ 2 NAD+ +
H2O
=
L-histidine
+ 2 NADH + 3 H+

Synonyms

GcHDH, HDH, HIS4 protein, HisD, histidinol dehydrogenase, HLDase, L-histidinol dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.23 histidinol dehydrogenase

Cloned

Cloned on EC 1.1.1.23 - histidinol dehydrogenase

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Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expressed in Spodoptera frugiperda, SF9 cells
expression in Escherichia coli
-
gene hisD, expression as glutathione S-transferase fusion protein with a thrombin cleavage site between tag and enzyme
gene hisD, overexpression in Escherichia coli strain BL21(DE3)
I6Y6Z1
recombinant expression of the His6-tagged enzyme in Escherichia coli strain BL21(DE3)
-