1.1.1.215: gluconate 2-dehydrogenase

This is an abbreviated version, for detailed information about gluconate 2-dehydrogenase, go to the full flat file.

Reaction

D-gluconate
+
NADP+
=
2-dehydro-D-gluconate
+
NADPH
+
H+

Synonyms

2-keto-D-gluconate reductase, 2-keto-D-gluconate-yielding D-gluconate dehydrogenase, 2-ketoaldonate reductase, 2-ketogluconate reductase, 2KGA reductase, 2KGR, 2KR, FAD-GADH, GAD, GADH, gluconate dehydrogenase, Gox0417, reductase, 2-ketogluconate

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.215 gluconate 2-dehydrogenase

pH Range

pH Range on EC 1.1.1.215 - gluconate 2-dehydrogenase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
4.5 - 8.5
Acetobacter ascendens
-
about half-maximal activity at pH 4.5 and 8.5, reduction of ketogluconate
5 - 9.2
-
about half-maximal activity at pH 5.0 and 9.2, reduction of ketogluconate
10 - 12
Acetobacter ascendens
-
about half-maximal activity at pH 10 and 12, oxidation of gluconate
10.8 - 12.5
-
about half-maximal activity at pH 10.8 and 12.5, oxidation of gluconate