1.1.1.215: gluconate 2-dehydrogenase

This is an abbreviated version, for detailed information about gluconate 2-dehydrogenase, go to the full flat file.

Reaction

D-gluconate
+
NADP+
=
2-dehydro-D-gluconate
+
NADPH
+
H+

Synonyms

2-keto-D-gluconate reductase, 2-keto-D-gluconate-yielding D-gluconate dehydrogenase, 2-ketoaldonate reductase, 2-ketogluconate reductase, 2KGA reductase, 2KGR, 2KR, FAD-GADH, GAD, GADH, gluconate dehydrogenase, Gox0417, reductase, 2-ketogluconate

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.215 gluconate 2-dehydrogenase

Substrates Products

Substrates Products on EC 1.1.1.215 - gluconate 2-dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2,5-diketo-D-gluconate + NADPH
5-keto-D-gluconate + NADP+
show the reaction diagram
2-dehydro-D-gluconate + NADPH
D-gluconate + NADP+
show the reaction diagram
2-keto-L-gulonate + NADPH
L-idonate + NADP+
show the reaction diagram
2-oxo-D-gluconate + NADH + H+
D-gluconate + NAD+
show the reaction diagram
2-oxo-D-gluconate + NADPH + H+
D-gluconate + NADP+
show the reaction diagram
2-oxo-L-gulonate + NADPH + H+
L-idonate + NADP+
show the reaction diagram
5-keto-D-gluconate + NADPH
D-gluconate + NADP+
show the reaction diagram
acetaldehyde + NADPH + H+
ethanol + NADP+
show the reaction diagram
-
poor substrate
-
-
?
D-galactonate + NADP+
2-dehydro-D-galactonate + NADPH
show the reaction diagram
D-gluconate + NADP+
2-dehydro-D-gluconate + NADPH
show the reaction diagram
D-gluconate + NADP+
2-dehydro-D-gluconate + NADPH + H+
show the reaction diagram
D-xylonate + NADPH
2-keto-D-xylonate + NADP+
show the reaction diagram
glyoxal + NADPH
?
show the reaction diagram
-
reduction at 33% the rate of 2-ketogluconate reduction
-
-
?
glyoxylate + NADPH
glycolate + NADP+
show the reaction diagram
-
reduction at 350% the rate of 2-ketogluconate reduction
-
?
hydroxypyruvate + NADPH
2,3-dihydroxypropanoate + NADP+
show the reaction diagram
-
reduction at 733% the rate of 2-keto-gluconate reduction
-
?
L-idonate + NADP+
2-keto-L-idonate + NADPH
show the reaction diagram
pyruvate + NADPH + H+
lactate + NADP+
show the reaction diagram
-
reduction at 7% the rate of 2-ketogluconate reduction
-
?
additional information
?
-