1.1.1.215: gluconate 2-dehydrogenase

This is an abbreviated version, for detailed information about gluconate 2-dehydrogenase, go to the full flat file.

Reaction

D-gluconate
+
NADP+
=
2-dehydro-D-gluconate
+
NADPH
+
H+

Synonyms

2-keto-D-gluconate reductase, 2-keto-D-gluconate-yielding D-gluconate dehydrogenase, 2-ketoaldonate reductase, 2-ketogluconate reductase, 2KGA reductase, 2KGR, 2KR, FAD-GADH, GAD, GADH, gluconate dehydrogenase, Gox0417, reductase, 2-ketogluconate

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.215 gluconate 2-dehydrogenase

KM Value

KM Value on EC 1.1.1.215 - gluconate 2-dehydrogenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
5
2,5-diketo-D-gluconate
Brevibacterium ketosoreductum
-
-
16
2-keto-D-galactonate
-
-
5.3
2-keto-D-gluconate
Acetobacter ascendens
-
-
91
2-keto-L-gulonate
-
-
5.16
2-oxo-D-gluconate
pH 7.0, 25C
0.86
5-Keto-D-gluconate
-
-
2.4
D-gluconate
-
-
4.4
gluconate
Acetobacter ascendens
-
-
0.38
glyoxylate
-
-
0.065
Hydroxypyruvate
-
-
0.051
NADH
pH 7.0, 25C
0.083 - 1.2
NADP+
0.0074 - 0.71
NADPH