1.1.1.10: L-xylulose reductase

This is an abbreviated version, for detailed information about L-xylulose reductase, go to the full flat file.

Reaction

xylitol
+
NADP+
=
L-xylulose
 +
NADPH
 +
H+

Synonyms

DCXR, dicarbonyl/L-xylulose reductase, L-xylulose reductase, LXR3, More, NAD(P)H-dependent xylose reductase, NADP(+)-dependent xylitol dehydrogenase, P31h, P34H, reductase, L-xylulose, XDH, XR, xylitol dehydrogenase, xylose reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.10 L-xylulose reductase

Cloned

Cloned on EC 1.1.1.10 - L-xylulose reductase

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Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
a recombinant Saccharomyces cerevisiae strain D-XR/ARSdR/XK, in which protein engineered NADP+-dependent XDH is expressed, shows 40% increased ethanol production and 23% decrease in xylitol excretion as compared with the reference strain D-XR/XDH/XK expressing the wild-type XDH
-
construction of a cDNA library, DNA sequence determination and analysis, subcloning in Escherichia coli DH5alpha, overexpression as His-tagged enzyme in Saccharomyces cerevisiae strain CEN.PK2
DNA sequence determination and analysis, expression in Escherichia coli strain BL21(DE3)
expressed in Escherichia coli as a His6 tag fusion protein
-
expressed in Escherichia coli BL21 (DE3) cells
-
expressed in Saccharomyces cerevisiae
expressed in Saccharomyces cerevisiae strain MA-R4
-
expressed in Saccharomyces cerevisiae strains MA-N2, MA-N3, MA-N4, and MA-N5
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expression in Saccharomyces cerevisiae
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expression of Pichia stipitis mutated XYL2 (D207/I208R/F209S or XYL2 S96C/S99C/Y102C/D207A/I208R/F209S) in Saccharomyces cerevisiae
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expression of wild-type and mutant enzymes in Escherichia coli
expression of wild-type and mutant enzymes in Escherichia coli strain BL21(DE3)
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gene dhs-21, DNA and amino acid sequence determination and analysis, the dhs-21 gene is physically mapped to the cosmid R11D1 between the sma-1 and mes-4genes on chromosome V, expression of His6-tagged enzyme. Spatial and temporal expression pattern of the DHS-21-GFP construct in transgenic worms, overview
gene lxr3, phylogenetic analysis, cloning in Escherichia coli strain JM109, expression of N-terminal His-tagged in Saccharomyces cerevisiae strain CEN.PK2-1D
Tn5 transposon transfer
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transgenic mice over-expressing dicarbonyl/L-xylulose reductase gene crossed with KK-A(y) diabetic model mice serve as an animal model for the metabolism of renal carbonyl compounds
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