1.1.1.10: L-xylulose reductase

This is an abbreviated version, for detailed information about L-xylulose reductase, go to the full flat file.

Reaction

xylitol
+
NADP+
=
L-xylulose
+
NADPH
+
H+

Synonyms

DCXR, dicarbonyl/L-xylulose reductase, L-xylulose reductase, LXR3, More, NAD(P)H-dependent xylose reductase, NADP(+)-dependent xylitol dehydrogenase, P31h, P34H, reductase, L-xylulose, XDH, XR, xylitol dehydrogenase, xylose reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.10 L-xylulose reductase

IC50 Value

IC50 Value on EC 1.1.1.10 - L-xylulose reductase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.00023
4-methyl-[1,2,3]-thiadiazole-5-carboxylic acid benzyloxyamide
Rattus norvegicus
-
IC50: 0.00023 mM for wild-type enzyme, 0.0019 mM for mutant enzyme L143F, 0.0018 mM for mutant enzyme H146L, 0.0029 mM for mutant enzyme W191S, 0.00079 mM for mutant enzyme W191F
0.0003
4-methylthiophene-2-carboxylic acid N'-(2,3,3-trichloroacryloyl)-hydrazide
Rattus norvegicus
-
IC50: 0.0003 mM for wild-type enzyme, 0.00056 mM for mutant enzyme L143F, 0.002 mM for mutant enzyme H146L, 0.0002 mM for mutant enzyme W191S, 0.0022 mM for mutant enzyme W191F