EC Number   |
Expression |
Reference  |
|---|
    2.3.3.8 | up |
enzyme activity increases with dissolved oxygen and upon ammonium depletion in an ammonium-limited culture |
-, 701861 |
| 2.3.3.8 | up |
there are about 3fold increased levels of the enzyme in glioblastoma pseudopodia compared to unmigrated cells |
704077 |
| 2.3.3.8 | down |
48 h after exhaustion of nitrogen in the culture, the enzyme shows marked decrease (84%) in activity. The enzyme activity decreases in a time period of 20-100 h during lipid accumulation |
-, 718581 |
| 2.3.3.8 | up |
the enzyme activity increases in the first 20 h during lipid accumulation |
-, 718581 |
| 2.3.3.8 | up |
sterol regulatory element binding protein-1 up-regulates the enzyme at mRNA level via Akt signaling |
718760 |
| 2.3.3.8 | down |
transcription of genes aclA and aclB is repressed by growth on acetate or ethanol |
-, 719383 |
| 2.3.3.8 | up |
enzyme mRNA and protein levels markedly (about 2.5fold) and quickly increase in activated macrophages. Tumour necrosis factor alpha and interferon gamma upregulate enzyme gene expression |
735597 |
| 2.3.3.8 | up |
high glucose upregulates ATP-citrate lyase expression |
755769 |
| 2.3.3.8 | down |
mRNA transcript levels decrease during normal macrophage differentiation from bone marrow precursors |
756281 |
| 2.3.3.8 | up |
overexpressed in many cancers. ACLY transcription is promoted by SREBP1 |
756333 |
