EC Number |
Metals/Ions |
Reference |
---|
2.3.3.13 | K+ |
Km: 80 mM, inhibitory at higher concentrations |
5664 |
2.3.3.13 | K+ |
required |
636520 |
2.3.3.13 | K+ |
strongly dependent on the presence of monovalent cations, K+ is most effective |
5664 |
2.3.3.13 | K+ |
the activator interacts with the catalytic TIM barrel domain, it does not induce any significant effect on the enzyme structure |
685842 |
2.3.3.13 | KCl |
100 mM, activity is increased 1.5fold |
727047 |
2.3.3.13 | Li+ |
can partially replace K+ in activation |
5664 |
2.3.3.13 | Li+ |
stimulates at low concentrations |
636525 |
2.3.3.13 | Mg2+ |
activates |
735592 |
2.3.3.13 | Mg2+ |
and Mn2+, best activators, ratio kcat/Kact 0.014 per s and M. Detailed kinetic analysis |
671604 |
2.3.3.13 | Mg2+ |
Mg2+ is capable of supporting robust catalytic activity |
718698 |