Reference on EC 5.1.1.18 - serine racemase and Organism(s) Mus musculus and UniProt Accession Q9QZX7
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Wang, L.Z.; Zhu, X.Z.
Spatiotemporal relationships among D-serine, serine racemase, and D-amino acid oxidase during mouse postnatal development
Acta Pharmacol. Sin.
24
965-974
2003
Mus musculus
Strisovsky, K.; Jiraskova, J.; Mikulova, A.; Rulisek, L.; Konvalinka, J.
Dual substrate and reaction specificity in mouse serine racemase: identification of high-affinity dicarboxylate substrate and inhibitors and analysis of the beta-eliminase activity
Biochemistry
44
13091-13100
2005
Mus musculus (Q9QZX7), Mus musculus
Dunlop, D.S.; Neidle, A.
Regulation of serine racemase activity by amino acids
Brain Res. Mol. Brain Res.
133
208-214
2005
Mus musculus
Strisovsky, K.; Jiraskova, J.; Barinka, C.; Majer, P.; Rojas, C.; Slusher, B.S.; Konvalinka, J.
Mouse brain serine racemase catalyzes specific elimination of L-serine to pyruvate
FEBS Lett.
535
44-48
2003
Mus musculus (Q9QZX7), Mus musculus
Cook, S.P.; Galve-Roperh, I.; Martinez del Pozo, A.; Rodriguez-Crespo, I.
Direct calcium binding results in activation of brain serine racemase
J. Biol. Chem.
277
27782-27792
2002
Mus musculus
Foltyn, V.N.; Bendikov, I.; De Miranda, J.; Panizzutti, R.; Dumin, E.; Shleper, M.; Li, P.; Toney, M.D.; Kartvelishvily, E.; Wolosker, H.
Serine racemase modulates intracellular D-serine levels through an alpha,beta-elimination activity
J. Biol. Chem.
280
1754-1763
2005
Mus musculus
Neidle, A.; Dunlop, D.S.
Allosteric regulation of mouse brain serine racemase
Neurochem. Res.
27
1719-1724
2002
Mus musculus
Stevens, E.R.; Esguerra, M.; Kim, P.M.; Newman, E.A.; Snyder, S.H.; Zahs, K.R.; Miller, R.F.
D-serine and serine racemase are present in the vertebrate retina and contribute to the physiological activation of NMDA receptors
Proc. Natl. Acad. Sci. USA
100
6789-6794
2003
Ambystoma tigrinum, Mus musculus, Rattus norvegicus
Kim, P.M.; Aizawa, H.; Kim, P.S.; Huang, A.S.; Wickramasinghe, S.R.; Kashani, A.H.; Barrow, R.K.; Huganir, R.L.; Ghosh, A.; Snyder, S.H.
Serine racemase: activation by glutamate neurotransmission via glutamate receptor interacting protein and mediation of neuronal migration
Proc. Natl. Acad. Sci. USA
102
2105-2110
2005
Mus musculus
Wolosker, H.; Blackshaw, S.; Snyder, S.H.
Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission
Proc. Natl. Acad. Sci. USA
96
13409-13414
1999
Mus musculus (Q9QZX7)
De Miranda, J.; Panizzutti, R.; Foltyn, V.N.; Wolosker, H.
Cofactors of serine racemase that physiologically stimulate the synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine
Proc. Natl. Acad. Sci. USA
99
14542-14547
2002
Mus musculus
Baumgart, F.; Mancheno, J.M.; Rodriguez-Crespo, I.
Insights into the activation of brain serine racemase by the multi-PDZ domain glutamate receptor interacting protein, divalent cations and ATP
FEBS J.
274
4561-4571
2007
Mus musculus
Dun, Y.; Duplantier, J.; Roon, P.; Martin, P.M.; Ganapathy, V.; Smith, S.B.
Serine racemase expression and D-serine content are developmentally regulated in neuronal ganglion cells of the retina
J. Neurochem.
104
970-978
2007
Mus musculus, Mus musculus C57/BL6J
Mustafa, A.K.; Kumar, M.; Selvakumar, B.; Ho, G.P.; Ehmsen, J.T.; Barrow, R.K.; Amzel, L.M.; Snyder, S.H.
Nitric oxide S-nitrosylates serine racemase, mediating feedback inhibition of D-serine formation
Proc. Natl. Acad. Sci. USA
104
2950-2955
2007
Mus musculus (Q9QZX7)
Hikida, T.; Mustafa, A.K.; Maeda, K.; Fujii, K.; Barrow, R.K.; Saleh, M.; Huganir, R.L.; Snyder, S.H.; Hashimoto, K.; Sawa, A.
Modulation of D-serine levels in brains of mice lacking PICK1
Biol. Psychiatry
63
997-1000
2008
Mus musculus
Miya, K.; Inoue, R.; Takata, Y.; Abe, M.; Natsume, R.; Sakimura, K.; Hongou, K.; Miyawaki, T.; Mori, H.
Serine racemase is predominantly localized in neurons in mouse brain
J. Comp. Neurol.
510
641-654
2008
Mus musculus
Inoue, R.; Hashimoto, K.; Harai, T.; Mori, H.
NMDA- and beta-amyloid1-42-induced neurotoxicity is attenuated in serine racemase knock-out mice
J. Neurosci.
28
14486-14491
2008
Mus musculus
Basu, A.C.; Tsai, G.E.; Ma, C.L.; Ehmsen, J.T.; Mustafa, A.K.; Han, L.; Jiang, Z.I.; Benneyworth, M.A.; Froimowitz, M.P.; Lange, N.; Snyder, S.H.; Bergeron, R.; Coyle, J.T.
Targeted disruption of serine racemase affects glutamatergic neurotransmission and behavior
Mol. Psychiatry
14
719-727
2008
Mus musculus
Hoffman, H.E.; Jiraskova, J.; Ingr, M.; Zvelebil, M.; Konvalinka, J.
Recombinant human serine racemase: enzymologic characterization and comparison with its mouse ortholog
Protein Expr. Purif.
63
62-67
2009
Homo sapiens, Mus musculus
Labrie, V.; Fukumura, R.; Rastogi, A.; Fick, L.J.; Wang, W.; Boutros, P.C.; Kennedy, J.L.; Semeralul, M.O.; Lee, F.H.; Baker, G.B.; Belsham, D.D.; Barger, S.W.; Gondo, Y.; Wong, A.H.; Roder, J.C.
Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model
Hum. Mol. Genet.
18
3227-3243
2009
Homo sapiens, Mus musculus, Mus musculus C57BL/6JJcl
Hoffman, H.E.; Jiraskova, J.; Cigler, P.; Sanda, M.; Schraml, J.; Konvalinka, J.
Hydroxamic acids as a novel family of serine racemase inhibitors: mechanistic analysis reveals different modes of interaction with the pyridoxal-5'-phosphate cofactor
J. Med. Chem.
52
6032-6041
2009
Mus musculus
Mustafa, A.K.; Ahmad, A.S.; Zeynalov, E.; Gazi, S.K.; Sikka, G.; Ehmsen, J.T.; Barrow, R.K.; Coyle, J.T.; Snyder, S.H.; Dore, S.
Serine racemase deletion protects against cerebral ischemia and excitotoxicity
J. Neurosci.
30
1413-1416
2010
Mus musculus
Mustafa, A.K.; van Rossum, D.B.; Patterson, R.L.; Maag, D.; Ehmsen, J.T.; Gazi, S.K.; Chakraborty, A.; Barrow, R.K.; Amzel, L.M.; Snyder, S.H.
Glutamatergic regulation of serine racemase via reversal of PIP2 inhibition
Proc. Natl. Acad. Sci. USA
106
2921-2926
2009
Mus musculus
Wolosker, H.
Serine racemase and the serine shuttle between neurons and astrocytes
Biochim. Biophys. Acta
1814
1558-1566
2011
Mus musculus
Foltyn, V.N.; Zehl, M.; Dikopoltsev, E.; Jensen, O.N.; Wolosker, H.
Phosphorylation of mouse serine racemase regulates D-serine synthesis
FEBS Lett.
584
2937-2941
2010
Mus musculus
Ding, X.; Ma, N.; Nagahama, M.; Yamada, K.; Semba, R.
Localization of D-serine and serine racemase in neurons and neuroglias in mouse brain
Neurol. Sci.
32
263-267
2011
Mus musculus
Wolosker, H.; Mori, H.
Serine racemase: an unconventional enzyme for an unconventional transmitter
Amino Acids
43
1895-1904
2012
Mus musculus, Mus musculus C57BL/6
Balu, D.T.; Takagi, S.; Puhl, M.D.; Benneyworth, M.A.; Coyle, J.T.
D-Serine and serine racemase are localized to neurons in the adult mouse and human forebrain
Cell. Mol. Neurobiol.
34
419-435
2014
Homo sapiens, Mus musculus
Ohide, H.; Miyoshi, Y.; Maruyama, R.; Hamase, K.; Konno, R.
D-Amino acid metabolism in mammals: biosynthesis, degradation and analytical aspects of the metabolic study
J. Chromatogr. B
879
3162-3168
2011
Homo sapiens, Mus musculus, Rattus norvegicus
Inoue, R.; Yoshihisa, Y.; Tojo, Y.; Okamura, C.; Yoshida, Y.; Kishimoto, J.; Luan, X.; Watanabe, M.; Mizuguchi, M.; Nabeshima, Y.; Hamase, K.; Matsunaga, K.; Shimizu, T.; Mori, H.
Localization of serine racemase and its role in the skin
J. Invest. Dermatol.
134
1618-1626
2014
Mus musculus, Mus musculus C57BL/6
Horio, M.; Kohno, M.; Fujita, Y.; Ishima, T.; Inoue, R.; Mori, H.; Hashimoto, K.
Role of serine racemase in behavioral sensitization in mice after repeated administration of methamphetamine
PLoS ONE
7
e35494
2012
Mus musculus
Uda, K.; Abe, K.; Dehara, Y.; Mizobata, K.; Edashige, Y.; Nishimura, R.; Radkov, A.D.; Moe, L.A.
Triple serine loop region regulates the aspartate racemase activity of the serine/aspartate racemase family
Amino Acids
49
1743-1754
2017
Acropora millepora, Crassostrea gigas (A0A0U5AKI6), Mus musculus (Q9QZX7), Mus musculus, Penaeus monodon (A0A0U4MRI4)
Talukdar, G.; Inoue, R.; Yoshida, T.; Ishimoto, T.; Yaku, K.; Nakagawa, T.; Mori, H.
Novel role of serine racemase in anti-apoptosis and metabolism
Biochim. Biophys. Acta
1861
3378-3387
2017
Mus musculus (Q9QZX7)
Canu, N.; Ciotti, M.T.; Pollegioni, L.
Serine racemase a key player in apoptosis and necrosis
Front. Synaptic Neurosci.
6
9
2014
Homo sapiens (Q9GZT4), Mus musculus (Q9QZX7)
