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Literature summary for 5.1.1.18 extracted from

  • Dun, Y.; Duplantier, J.; Roon, P.; Martin, P.M.; Ganapathy, V.; Smith, S.B.
    Serine racemase expression and D-serine content are developmentally regulated in neuronal ganglion cells of the retina (2007), J. Neurochem., 104, 970-978.
    View publication on PubMed
Search for more literature for 5.1.1.18

Cloned(Commentary)

Cloned (Comment) Organism
quantitative expression analysis Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
38000
-
 x * 38000, SDS-PAGE Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-serine Mus musculus developmental regulation of enzyme expression in neuronal ganglion cells of the retina, overview, D-serine is the endogenous ligand for the glycine modulatory binding site of the NMDA receptor D-serine
-
 ?
L-serine Mus musculus C57/BL6J developmental regulation of enzyme expression in neuronal ganglion cells of the retina, overview, D-serine is the endogenous ligand for the glycine modulatory binding site of the NMDA receptor D-serine
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-
Mus musculus
-
 C57BL/6J mice
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Mus musculus C57/BL6J
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 C57BL/6J mice
-

Source Tissue

Source Tissue Comment Organism Textmining
eye
-
 Mus musculus
-
ganglion primary ganglion cell, robust expression of serine racemase Mus musculus
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retina neuronal ganglion cells Mus musculus
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retina intact retina of 1-3 day, 3 week, and 18 week old mouse. Robust expression of serine racemase, levels are developmentally regulated, with high levels during the early postnatal period, but diminishing considerably in the mature retina. D-Serine levels are regulated accordingly. Mus musculus
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retinal ganglion cell developmental regulation of enzyme expression, in situ hybridization analysis, overview, D-serine levels are quite high in ganglion cells of neonatal retinas and decreasing rapidly postnatally Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-serine
-
 Mus musculus D-serine
-
 ?
L-serine developmental regulation of enzyme expression in neuronal ganglion cells of the retina, overview, D-serine is the endogenous ligand for the glycine modulatory binding site of the NMDA receptor Mus musculus D-serine
-
 ?
L-serine
-
 Mus musculus C57/BL6J D-serine
-
 ?
L-serine developmental regulation of enzyme expression in neuronal ganglion cells of the retina, overview, D-serine is the endogenous ligand for the glycine modulatory binding site of the NMDA receptor Mus musculus C57/BL6J D-serine
-
 ?

Subunits

Subunits Comment Organism
? x * 38000, SDS-PAGE Mus musculus