Information on EC - phenylalanine/tyrosine ammonia-lyase

for references in articles please use BRENDA:EC4.3.1.25
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     4 Lyases
         4.3 Carbon-nitrogen lyases
             4.3.1 Ammonia-lyases
       phenylalanine/tyrosine ammonia-lyase
IUBMB Comments
This enzyme is a member of the aromatic amino acid lyase family, other members of which are EC (histidine ammonia-lyase), EC (tyrosine ammonia-lyase) and EC (phenylalanine ammonia-lyase). The enzyme from some monocots, including maize, and from the yeast Rhodosporidium toruloides, deaminate L-phenylalanine and L-tyrosine with similar catalytic efficiency . The enzyme contains the cofactor 3,5-dihydro-5-methylidene-4H-imidazol-4-one (MIO), which is common to this family . This unique cofactor is formed autocatalytically by cyclization and dehydration of the three amino-acid residues alanine, serine and glycine .
Specify your search results
Select one or more organisms in this record: ?
Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
PAL, PAL/TAL, PAL4, phenylalanine-tyrosine ammonia lyase, PTAL, RtPAL, Sb04g026510, Sb06g022740, SbPAL1, more
L-phenylalanine = trans-cinnamate + NH3
show the reaction diagram
L-tyrosine = trans-p-hydroxycinnamate + NH3
show the reaction diagram
Select items on the left to see more content.