Literature summary for 4.3.1.25 extracted from

Castaneda, M.T.; Adachi, O.; Hours, R.A.
Reduction of L-phenylalanine in protein hydrolysates using L-phenylalanine ammonia-lyase from Rhodosporidium toruloides (2015), J. Ind. Microbiol. Biotechnol., 42, 1299-1307 .

Search for more literature for 4.3.1.25

Application

Application	Comment	Organism
food industry	the enzyme is a useful biocatalyst for removal of L-phenylalanine from protein hydrolysates, which can be evaluated as potential ingredients in foodstuffs for phenylketonuria patients. The enzyme is also capable to catalyze the deamination of L-tyrosine to p-coumaric acid but at a substantially low reaction rate. Therefore, the final content of L-Tyr in samples treated with L-phenylalanine ammonia-lyase should be analyzed in each case and taken in consideration to avoid its deficiency in phenylketonuria patients	Rhodotorula toruloides
nutrition	the enzyme is a useful biocatalyst for removal of L-phenylalanine from protein hydrolysates, which can be evaluated as potential ingredients in foodstuffs for phenylketonuria patients. The enzyme is also capable to catalyze the deamination of L-tyrosine to p-coumaric acid but at a substantially low reaction rate. Therefore, the final content of L-Tyr in samples treated with L-phenylalanine ammonia-lyase should be analyzed in each case and taken in consideration to avoid its deficiency in phenylketonuria patients	Rhodotorula toruloides
pharmacology	the enzyme is a useful biocatalyst for removal of L-phenylalanine from protein hydrolysates, which can be evaluated as potential ingredients in foodstuffs for phenylketonuria patients. The enzyme is also capable to catalyze the deamination of L-tyrosine to p-coumaric acid but at a substantially low reaction rate. Therefore, the final content of L-Tyr in samples treated with L-phenylalanine ammonia-lyase should be analyzed in each case and taken in consideration to avoid its deficiency in phenylketonuria patients	Rhodotorula toruloides

Organism

Organism	UniProt	Comment	Textmining
Rhodotorula toruloides	P11544	-	-
Rhodotorula toruloides NBRC 0559	P11544	-	-

Purification (Commentary)

Purification (Comment)	Organism
partial	Rhodotorula toruloides

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-phenylalanine	-	Rhodotorula toruloides	trans-cinnamate + NH3	-	?
L-phenylalanine	-	Rhodotorula toruloides NBRC 0559	trans-cinnamate + NH3	-	?

Synonyms

Synonyms	Comment	Organism
PAL	-	Rhodotorula toruloides

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
30	-	assay at	Rhodotorula toruloides

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
8.5	-	assay at	Rhodotorula toruloides

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Release 2023.1 (January 2023)