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Reference on EC 2.7.11.22 - cyclin-dependent kinase and Organism(s) Rattus norvegicus and UniProt Accession Q63699

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hirose, T.; Tamaru, T.; Okumura, N.; Nagai, K.; Okada, M.
PCTAIRE 2, a Cdc2-related serine/threonine kinase, is predominantly expressed in terminally differentiated neurons
Eur. J. Biochem.
249
481-488
1997
Rattus norvegicus (O35831), Rattus norvegicus (O35832)
Manually annotated by BRENDA team
Matsushime, H.; Jinno, A.; Takagi, N.; Shibuya, M.
A novel mammalian protein kinase gene (mak) is highly expressed in testicular germ cells at and after meiosis
Mol. Cell. Biol.
10
2261-2268
1990
Rattus norvegicus (P20793), Homo sapiens (P20794)
Manually annotated by BRENDA team
Cho, F.S.; Phillips, K.S.; Khan, S.A.; Weaver, T.E.
Cloning of the rat cyclin-dependent kinase 4 cDNA: implication in proliferation-dependent expression in rat tissues
Biochem. Biophys. Res. Commun.
191
860-865
1993
Rattus norvegicus (P35426)
Manually annotated by BRENDA team
Riabowol, K.; Draetta, G.; Brizuela, L.; Vandre, D.; Beach, D.
The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells
Cell
57
393-401
1989
Rattus norvegicus (P39951)
Manually annotated by BRENDA team
Kerr, M.; Fischer, J.E.; Purushotham, K.R.; Gao, D.; Nakagawa, Y.; Maeda, N.; Ghanta, V.; Hiramoto, R.; Chegini, N.; Humphreys-Beher, M.G.
Characterization of the synthesis and expression of the GTA-kinase from transformed and normal rodent cells
Biochim. Biophys. Acta
1218
375-387
1994
Rattus norvegicus (P46892)
Manually annotated by BRENDA team
Xiong, Y.; Zhang, H.; Beach, D.
D Type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA
Cell
71
505-514
1992
Rattus norvegicus (Q03114)
Manually annotated by BRENDA team
Hellmich, M.R.; Pant, H.C.; Wada, E.; Battey, J.F.
Neuronal cdc2-like kinase: a cdc2-related protein kinase with predominantly neuronal expression
Proc. Natl. Acad. Sci. USA
89
10867-10871
1992
Rattus norvegicus (Q03114)
Manually annotated by BRENDA team
Kotani, S.; Endo, T.; Kitagawa, M.; Higashi, H.; Onaya, T.
A variant form of cyclin-dependent kinase 2 (Cdk2) in a malignantly transformed rat thyroid (FRTL-Tc) cell line
Oncogene
10
663-669
1995
Rattus norvegicus (Q63699)
Manually annotated by BRENDA team
Hosokawa, Y.; Yang, M.; Kaneko, S.; Tanaka, M.; Nakashima, K.
Synergistic gene expressions of cyclin E, cdk2, cdk5 and E2F-1 during the prolactin-induced G1/S transition in rat Nb2 pre-T lymphoma cells
Biochem. Mol. Biol. Int.
37
393-399
1995
Rattus norvegicus (Q63699)
Manually annotated by BRENDA team
Darios, F.; Muriel, M.P.; Khondiker, M.E.; Brice, A.; Ruberg, M.
Neurotoxic calcium transfer from endoplasmic reticulum to mitochondria is regulated by cyclin-dependent kinase 5-dependent phosphorylation of tau
J. Neurosci.
25
4159-4168
2005
Rattus norvegicus
Manually annotated by BRENDA team
Kesavapany, S.; Li, B.S.; Amin, N.; Zheng, Y.L.; Grant, P.; Pant, H.C.
Neuronal cyclin-dependent kinase 5: role in nervous system function and its specific inhibition by the Cdk5 inhibitory peptide
Biochim. Biophys. Acta
1697
143-153
2004
Danio rerio, Saccharomyces cerevisiae, Caenorhabditis elegans, Canis lupus familiaris, Drosophila melanogaster, Homo sapiens, Doryteuthis pealeii, Mus musculus, Rattus norvegicus, Sus scrofa
Manually annotated by BRENDA team
Andres, V.
Control of vascular cell proliferation and migration by cyclin-dependent kinase signalling: new perspectives and therapeutic potential
Cardiovasc. Res.
63
11-21
2004
Homo sapiens, Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Li, B.S.; Ma, W.; Jaffe, H.; Zheng, Y.; Takahashi, S.; Zhang, L.; Kulkarni, A.B.; Pant, H.C.
Cyclin-dependent kinase-5 is involved in neuregulin-dependent activation of phosphatidylinositol 3-kinase and Akt activity mediating neuronal survival
J. Biol. Chem.
278
35702-35709
2003
Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Zhu, Y.S.; Saito, T.; Asada, A.; Maekawa, S.; Hisanaga, S.
Activation of latent cyclin-dependent kinase 5 (Cdk5)-p35 complexes by membrane dissociation
J. Neurochem.
94
1535-1545
2005
Rattus norvegicus
Manually annotated by BRENDA team
Rideout, H.J.; Wang, Q.; Park, D.S.; Stefanis, L.
Cyclin-dependent kinase activity is required for apoptotic death but not inclusion formation in cortical neurons after proteasomal inhibition
J. Neurosci.
23
1237-1245
2003
Rattus norvegicus
Manually annotated by BRENDA team
Zhen, X.; Goswami, S.; Abdali, S.A.; Gil, M.; Bakshi, K.; Friedman, E.
Regulation of cyclin-dependent kinase 5 and calcium/calmodulin-dependent protein kinase II by phosphatidylinositol-linked dopamine receptor in rat brain
Mol. Pharmacol.
66
1500-1507
2004
Rattus norvegicus
Manually annotated by BRENDA team
Hisanaga, S.; Saito, T.
The regulation of cyclin-dependent kinase 5 activity through the metabolism of p35 or p39 Cdk5 activator
Neurosignals
12
221-229
2003
Homo sapiens, Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Li, T.; Hawkes, C.; Qureshi, H.Y.; Kar, S.; Paudel, H.K.
Cyclin-dependent protein kinase 5 primes microtubule-associated protein tau site-specifically for glycogen synthase kinase 3beta
Biochemistry
45
3134-3145
2006
Bos taurus, Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Avraham, E.; Rott, R.; Liani, E.; Szargel, R.; Engelender, S.
Phosphorylation of Parkin by the cyclin-dependent kinase 5 at the linker region modulates its ubiquitin-ligase activity and aggregation
J. Biol. Chem.
282
12842-12850
2007
Homo sapiens, Rattus norvegicus, Rattus norvegicus (Q03114)
Manually annotated by BRENDA team
Kino, T.; Ichijo, T.; Amin, N.D.; Kesavapany, S.; Wang, Y.; Kim, N.; Rao, S.; Player, A.; Zheng, Y.L.; Garabedian, M.J.; Kawasaki, E.; Pant, H.C.; Chrousos, G.P.
Cyclin-dependent kinase 5 differentially regulates the transcriptional activity of the glucocorticoid receptor through phosphorylation: clinical implications for the nervous system response to glucocorticoids and stress
Mol. Endocrinol.
21
1552-1568
2007
Rattus norvegicus
Manually annotated by BRENDA team
Pareek, T.K.; Keller, J.; Kesavapany, S.; Pant, H.C.; Iadarola, M.J.; Brady, R.O.; Kulkarni, A.B.
Cyclin-dependent kinase 5 activity regulates pain signaling
Proc. Natl. Acad. Sci. USA
103
791-796
2006
Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Moore, N.L.; Narayanan, R.; Weigel, N.L.
Cyclin dependent kinase 2 and the regulation of human progesterone receptor activity
Steroids
72
202-209
2007
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Chen, X.; Huang, T.; Zhang, J.; Song, J.; Chen, L.; Zhu, Y.
Involvement of calpain and p25 of CDK5 pathway in ginsenoside Rb1s attenuation of beta-amyloid peptide25-35-induced tau hyperphosphorylation in cortical neurons
Brain Res.
1200
99-106
2008
Rattus norvegicus
Manually annotated by BRENDA team
Meuer, K.; Suppanz, I.E.; Lingor, P.; Planchamp, V.; Goericke, B.; Fichtner, L.; Braus, G.H.; Dietz, G.P.; Jakobs, S.; Baehr, M.; Weishaupt, J.H.
Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis
Cell Death Differ.
14
651-661
2007
Rattus norvegicus
Manually annotated by BRENDA team
Saito, T.; Konno, T.; Hosokawa, T.; Asada, A.; Ishiguro, K.; Hisanaga, S.
p25/cyclin-dependent kinase 5 promotes the progression of cell death in nucleus of endoplasmic reticulum-stressed neurons
J. Neurochem.
102
133-140
2007
Rattus norvegicus
Manually annotated by BRENDA team
Anne, S.L.; Saudou, F.; Humbert, S.
Phosphorylation of huntingtin by cyclin-dependent kinase 5 is induced by DNA damage and regulates wild-type and mutant huntingtin toxicity in neurons
J. Neurosci.
27
7318-7328
2007
Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Amin, N.D.; Zheng, Y.L.; Kesavapany, S.; Kanungo, J.; Guszczynski, T.; Sihag, R.K.; Rudrabhatla, P.; Albers, W.; Grant, P.; Pant, H.C.
Cyclin-dependent kinase 5 phosphorylation of human septin SEPT5 (hCDCrel-1) modulates exocytosis
J. Neurosci.
28
3631-3643
2008
Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Hsiao, Y.H.; Chen, P.S.; Yeh, S.H.; Lin, C.H.; Gean, P.W.
N-acetylcysteine prevents beta-amyloid toxicity by a stimulatory effect on p35/cyclin-dependent kinase 5 activity in cultured cortical neurons
J. Neurosci. Res.
86
2685-2695
2008
Rattus norvegicus
Manually annotated by BRENDA team
Wang, Q.S.; Zhang, C.L.; Hou, L.Y.; Zhao, X.L.; Yang, X.W.; Xie, K.Q.
Involvement of cyclin-dependent kinase 5 in 2,5-hexanedione-induced neuropathy
Toxicology
248
1-7
2008
Rattus norvegicus
Manually annotated by BRENDA team
Chan, K.C.; Ho, H.H.; Peng, C.H.; Lan, K.P.; Lin, M.C.; Chen, H.M.; Wang, C.J.
Polyphenol-rich extract from mulberry leaf inhibits vascular smooth muscle cell proliferation involving upregulation of p53 and inhibition of cyclin-dependent kinase
J. Agric. Food Chem.
58
2536-2542
2010
Rattus norvegicus
Manually annotated by BRENDA team
Mairet-Coello, G.; Tury, A.; DiCicco-Bloom, E.
Insulin-like growth factor-1 promotes G1/S cell cycle progression through bidirectional regulation of cyclins and cyclin-dependent kinase inhibitors via the phosphatidylinositol 3-kinase/Akt pathway in developing rat cerebral cortex
J. Neurosci.
29
775-788
2009
Rattus norvegicus
Manually annotated by BRENDA team
Ivanov, A.; Tyzio, R.; Zilberter, Y.; Ben-Ari, Y.
(R)-roscovitine, a cyclin-dependent kinase inhibitor, enhances tonic GABA inhibition in rat hippocampus
Neuroscience
156
277-288
2008
Rattus norvegicus
Manually annotated by BRENDA team