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Information on EC 2.6.1.16 - glutamine-fructose-6-phosphate transaminase (isomerizing)

for references in articles please use BRENDA:EC2.6.1.16
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IUBMB Comments
Although the overall reaction is that of a transferase, the mechanism involves the formation of ketimine between fructose 6-phosphate and a 6-amino group from a lysine residue at the active site, which is subsequently displaced by ammonia (transamidination).
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
gfpt1, gfat1, glms ribozyme, glucosamine-6-phosphate synthase, glutamine:fructose-6-phosphate amidotransferase, glcn-6-p synthase, gfat2, glutamine fructose-6-phosphate amidotransferase, g-6-p synthase, glucosamine 6-phosphate synthase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate
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