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Information on EC 2.4.1.346 - phosphatidyl-myo-inositol dimannoside synthase

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EC Tree
     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.346 phosphatidyl-myo-inositol dimannoside synthase
IUBMB Comments
Requires Mg2+. The enzyme, found in Corynebacteriales, is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIMs).
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
GDP-mannose-dependent monoacylated alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase, guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase, mannoslytransferase PimB', mannosyltransferase PimB, mannosyltransferase PimB', MgtA, MSMEG_4253, NCgl2106, PimB, pimB', more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
GDP-alpha-D-mannose + 2-O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol = GDP + 2-O-(6-O-acyl-alpha-D-mannosyl)-6-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol
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(2)
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GDP-alpha-D-mannose + 2-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol = GDP + 2,6-di-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol
show the reaction diagram
(1)
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