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Literature summary for 2.4.1.346 extracted from

  • Mishra, A.K.; Batt, S.; Krumbach, K.; Eggeling, L.; Besra, G.S.
    Characterization of the Corynebacterium glutamicum deltapimB deltamgtA double deletion mutant and the role of Mycobacterium tuberculosis orthologues Rv2188c and Rv0557 in glycolipid biosynthesis (2009), J. Bacteriol., 191, 4465-4472.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.1.346

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GDP-alpha-D-mannose + 2-O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol Mycobacterium tuberculosis
-
 GDP + 2-O-(6-O-acyl-alpha-D-mannosyl)-6-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol
-
 ?
GDP-alpha-D-mannose + 2-O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol Mycobacterium tuberculosis ATCC 25618
-
 GDP + 2-O-(6-O-acyl-alpha-D-mannosyl)-6-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol
-
 ?
GDP-alpha-D-mannose + 2-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol Mycobacterium tuberculosis
-
 GDP + 2,6-di-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol
-
 ?
GDP-alpha-D-mannose + 2-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol Mycobacterium tuberculosis ATCC 25618
-
 GDP + 2,6-di-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol
-
 ?

Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis P9WMY5
-
-
Mycobacterium tuberculosis P9WMZ3
-
-
Mycobacterium tuberculosis ATCC 25618 P9WMY5
-
-
Mycobacterium tuberculosis ATCC 25618 P9WMZ3
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDP-alpha-D-mannose + 2-O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol
-
 Mycobacterium tuberculosis GDP + 2-O-(6-O-acyl-alpha-D-mannosyl)-6-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol
-
 ?
GDP-alpha-D-mannose + 2-O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol
-
 Mycobacterium tuberculosis ATCC 25618 GDP + 2-O-(6-O-acyl-alpha-D-mannosyl)-6-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol
-
 ?
GDP-alpha-D-mannose + 2-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol
-
 Mycobacterium tuberculosis GDP + 2,6-di-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol
-
 ?
GDP-alpha-D-mannose + 2-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol
-
 Mycobacterium tuberculosis ATCC 25618 GDP + 2,6-di-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol
-
 ?
additional information enzyme accepts 1,2-di-O-C16/C18:1-(1->4)-(alpha-D-glucopyranosyluronic acid)-(1->3)-glycerol as equally efficient substrate Mycobacterium tuberculosis ?
-
 ?
additional information enzyme accepts 1,2-di-O-C16/C18:1-(1->4)-(alpha-D-glucopyranosyluronic acid)-(1->3)-glycerol as equally efficient substrate Mycobacterium tuberculosis ATCC 25618 ?
-
 ?

Synonyms

Synonyms Comment Organism
MgtA
-
 Mycobacterium tuberculosis
Rv0557
-
 Mycobacterium tuberculosis
Rv2188c
-
 Mycobacterium tuberculosis

General Information

General Information Comment Organism
physiological function characterization of a PimB MgtA double deletion mutant. Gene product of Rv2188c acts as an Ac1PIM1:mannosyltransferase PimB and the product of Rv0557 acts as a GlcAGroAc2:mannosyltransferase MgtA Mycobacterium tuberculosis