Information on EC 2.4.1.221 - peptide-O-fucosyltransferase

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EC Tree
     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.221 peptide-O-fucosyltransferase
IUBMB Comments
Involved in the biosynthesis of O-fucosylated epidermal growth factor (EGF) and thrombospondin type 1 repeats. The attachment of O-linked fucose to serine or threonine occurs on EGF domains within the sequence Cys-Xaa-Xaa-Gly-Gly-Ser/Thr-Cys.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
alpha-6-fucosyltransferase, At3g05320, AtOFT1, core alpha6FucT, fucosyltransferase, guanosine diphosphofucose-glycoprotein, FUT2, GDP-fucose glycoprotein fucosyltransferase, GDP-fucose protein O-fucosyltransferase, GDP-fucose protein O-fucosyltransferase 1, GDP-fucose protein O-fucosyltransferase 2, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
transfers an alpha-L-fucosyl residue from GDP-beta-L-fucose to the serine hydroxy group of a protein acceptor
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PATHWAY SOURCE
PATHWAYS
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