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Information on EC 2.4.1.221 - peptide-O-fucosyltransferase

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EC Tree
     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.221 peptide-O-fucosyltransferase
IUBMB Comments
Involved in the biosynthesis of O-fucosylated epidermal growth factor (EGF) and thrombospondin type 1 repeats. The attachment of O-linked fucose to serine or threonine occurs on EGF domains within the sequence Cys-Xaa-Xaa-Gly-Gly-Ser/Thr-Cys.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
pofut1, protein o-fucosyltransferase 1, pofut2, ofut1, o-fucosyltransferase, o-fut1, o-fuct-1, protein o-fucosyltransferase 2, alpha-6-fucosyltransferase, o-fucosyltransferase 1, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
transfers an alpha-L-fucosyl residue from GDP-beta-L-fucose to the serine hydroxy group of a protein acceptor
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PATHWAY SOURCE
PATHWAYS
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