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Information on EC 2.3.3.1 - citrate (Si)-synthase

for references in articles please use BRENDA:EC2.3.3.1

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IUBMB Comments

The stereospecificity of this enzyme is opposite to that of EC 2.3.3.3, citrate (Re)-synthase, which is found in some anaerobes. Citrate synthase for which the stereospecificity with respect to C-2 of oxaloacetate has not been established are included in EC 2.3.3.16, citrate synthase (unknown stereospecificity).

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea

Synonyms
citrate synthase, citrate (si)-synthase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
acetyl-CoA + H2O + oxaloacetate = citrate + CoA
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
ethene biosynthesis V (engineered), glyoxylate cycle, methylaspartate cycle, mixed acid fermentation, nitrogen remobilization from senescing leaves, partial TCA cycle (obligate autotrophs), TCA cycle I (prokaryotic), TCA cycle II (plants and fungi), TCA cycle III (animals), TCA cycle IV (2-oxoglutarate decarboxylase), TCA cycle V (2-oxoglutarate synthase), TCA cycle VI (Helicobacter), TCA cycle VII (acetate-producers)