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EC 2.7.11.17 Details
EC number
2.7.11.17
Accepted name
Ca2+/calmodulin-dependent protein kinase
Reaction
ATP + a protein = ADP + a phosphoprotein
Other name(s)
ATP:caldesmon O-phosphotransferase,
caldesmon kinase,
caldesmon kinase (phosphorylating),
Ca2+/calmodulin-dependent microtubule-associated protein 2 kinase,
Ca2+/calmodulin-dependent protein kinase 1,
Ca2+/calmodulin-dependent protein kinase II,
Ca2+/calmodulin-dependent protein kinase IV,
Ca2+/calmodulin-dependent protein kinase kinase,
Ca2+/calmodulin-dependent protein kinase kinase β,
calmodulin-dependent kinase II,
CaM kinase,
CaM kinase II,
CAM PKII,
CaM-regulated serine/threonine kinase,
CaMKI,
CaMKII,
CaMKIV,
CaMKKα,
CaMKKβ,
microtubule-associated protein 2 kinase,
STK20
Systematic name
ATP:protein phosphotransferase (Ca2+/calmodulin-dependent)
CAS registry number
141467-21-2
Comment
Requires calmodulin and Ca2+ for activity. A wide range of proteins can act as acceptor, including vimentin, synapsin, glycogen synthase, myosin light chains and the microtubule-associated tau protein. Not identical with EC 2.7.11.18 (myosin-light-chain kinase) or EC 2.7.11.26 (tau-protein kinase).
History
created 1989 as EC 2.7.1.123, transferred 2005 to EC 2.7.11.17 (EC 2.7.1.120 incorporated 2005)
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