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Synonyms
amp-activated protein kinase, glycogen synthase kinase, protein kinase 1, gsk3b, extracellular-regulated kinase, gsk-3 beta, protein kinase-a, srpk2, gsk-3alpha, ttbk2,
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AMP-activated protein kinase
brain proteinkinase PK40erk
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cAMP-dependent protein kinase A
cyclin-dependent kinase 5
cyclin-dependent kinase 5/p39
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cyclin-dependent kinase-5
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EC 2.7.1.135
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formerly
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extracellular-regulated kinase
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glycogen synthase kinase
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glycogen synthase kinase 3
glycogen synthase kinase 3 beta
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glycogen synthase kinase 3-beta
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glycogen synthase kinase 3beta
glycogen synthase kinase-3
glycogen synthase kinase-3 alpha
glycogen synthase kinase-3 homolog
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glycogen synthase kinase-3 homolog MsK-1
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glycogen synthase kinase-3 homolog MsK-2
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glycogen synthase kinase-3 homolog MsK-3
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glycogen synthase kinase-3alphabeta
glycogen synthase kinase-3beta
glycogen synthase kinase-3beta1
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glycogen synthase kinase-3beta2
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glycogen synthetase kinase-3 beta
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GSK-3/shaggy-like protein kinase
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p25-Cdk5 kinase complex
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protein tau kinase
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serine-threonine kinase
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serine/threonine-protein kinase 2
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serine/threonine-protein kinase MDS1/RIM11
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serine/threonine-protein kinase MRK1
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serum- and glucocorticoid-induced protein kinase 1
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Sgg
Drosophila sp. (in: flies)
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SHAGGY-related protein kinase
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shaggy-related protein kinase alpha
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shaggy-related protein kinase beta
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shaggy-related protein kinase delta
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shaggy-related protein kinase eta
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shaggy-related protein kinase gamma
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shaggy-related protein kinase iota
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shaggy-related protein kinase kappa
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shaggy-related protein kinase NtK-1
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shaggy-related protein kinase theta
shaggy/zeste white-3
Drosophila sp. (in: flies)
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stress activated kinase/c-jun N-terminal kinase
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Syk
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common tyrosine kinase of tau and alpha-synuclein
tau factor protein kinase (phosphorylating)
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tau protein kinase I/glycogen synthase kinase 3beta
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tau protein kinase I/GSK-3beta/kinaseFA
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tau protein kinase II (cdk5/p20)
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tau protein kinase II system
Tau tubulin binding kinase1
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Tau tubulin binding kinase2
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tau-protein kinase II
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AMP-activated protein kinase
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AMP-activated protein kinase
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AMPK
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cAMP-dependent protein kinase A
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cAMP-dependent protein kinase A
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Cdk5
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cyclin-dependent kinase 5
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cyclin-dependent kinase 5
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cyclin-dependent kinase 5
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glycogen synthase kinase 3
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glycogen synthase kinase 3
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glycogen synthase kinase 3beta
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glycogen synthase kinase 3beta
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glycogen synthase kinase 3beta
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glycogen synthase kinase 3beta
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glycogen synthase kinase-3
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glycogen synthase kinase-3
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glycogen synthase kinase-3
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glycogen synthase kinase-3
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glycogen synthase kinase-3
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glycogen synthase kinase-3
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glycogen synthase kinase-3
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glycogen synthase kinase-3
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glycogen synthase kinase-3
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glycogen synthase kinase-3
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glycogen synthase kinase-3 alpha
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glycogen synthase kinase-3 alpha
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glycogen synthase kinase-3 alpha
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glycogen synthase kinase-3alphabeta
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glycogen synthase kinase-3alphabeta
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glycogen synthase kinase-3beta
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glycogen synthase kinase-3beta
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glycogen synthase kinase-3beta
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glycogen synthase kinase-3beta
Drosophila sp. (in: flies)
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glycogen synthase kinase-3beta
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662690, 674847, 702646, 703016, 704796, 704801, 704992, 705240, 705325, 705326, 705328, 705412, 705796, 705916, 706016
glycogen synthase kinase-3beta
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isoform
glycogen synthase kinase-3beta
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glycogen synthase kinase-3beta
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glycogen synthase kinase-3beta
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glycogen synthase kinase-3beta
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glycogen synthase kinase-3beta
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693729, 693777, 702959, 703088, 703234, 703382, 703942, 704008, 704493, 705253, 705453, 705898, 705942
glycogen synthase kinase-3beta
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glycogen synthase kinase-3beta
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glycogen synthase kinase-3beta
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GSK-3
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GSK-3 beta
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GSK-3alpha
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isoform
GSK-3beta
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GSK-3beta
Drosophila sp. (in: flies)
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GSK-3beta
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662261, 662690, 674847, 702646, 703016, 704796, 704801, 704992, 705240, 705325, 705326, 705328, 705412, 705796, 705916, 706016
GSK-3beta
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693729, 693777, 703088, 703234, 703382, 703942, 704008, 704493, 705253, 705453, 705898, 705942
GSK-3beta1
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isoform
GSK-3beta2
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neuron-specific isoform
GSK3
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GSK3alpha
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GSK3beta
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PKA
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shaggy-related protein kinase theta
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shaggy-related protein kinase theta
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tau kinase
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tau protein kinase
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tau protein kinase I
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tau protein kinase II system
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tau protein kinase II system
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tau tubulin kinase 2
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tau-protein kinase I
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tau-tubulin kinase
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Tau-tubulin kinase 1
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TPK
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TPKI
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TPKI/GSK-3beta
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TPKI/GSK3beta
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TTBK1
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TTBK2
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TTK
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additional information
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see also EC 2.7.11.1
additional information
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cf. EC 2.7.11.1
additional information
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see also EC 2.7.11.1
additional information
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see also EC 2.7.11.1
additional information
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see also EC 2.7.11.1
additional information
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see also EC 2.7.11.1
additional information
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see also EC 2.7.11.1
additional information
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see also EC 2.7.11.1 and EC 2.7.11.11
additional information
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see also EC 2.7.11.1 and EC 2.7.11.22
additional information
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see also EC 2.7.11.22
additional information
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CDK5 is a unique member of the CDK family, see also EC 2.7.11.22
additional information
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see also EC 2.7.11.1 and EC 2.7.11.22
additional information
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see also EC 2.7.11.22
additional information
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see also EC 2.7.11.1 and EC 2.7.11.11
additional information
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see also EC 2.7.11.22
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ATP + tau-protein = ADP + O-phospho-tau-protein
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ATP + [tau-protein] = ADP + O-phospho-[tau-protein]
ATP + [tau-protein] = ADP + O-phospho-[tau-protein]
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ATP + [tau-protein] = ADP + O-phospho-[tau-protein]
activation loop structure, substrate binding structure, and catalytic site structure and mechanism
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ATP + [tau-protein] = ADP + O-phospho-[tau-protein]
glycogen synthase kinase-3beta also performs serine/threonine protein kinase reaction, EC 2.7.11.1, with other substrates than tau, e.g. it phosphorylates the glycogen synthase
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ATP + [tau-protein] = ADP + O-phospho-[tau-protein]
GSK-3 and PKA catalyze tau phosphorylation in the brain, while GSK-3 performs phosphorylation of glycogen synthase, EC 2.7.11.1, and other proteins in different tissues, and PKA performs phosphorylation of other proteins in different tissues
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ATP + alpha-actin
ADP + p35
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?
ATP + alpha-casein
ADP + alpha-casein phosphate
ATP + alpha-synuclein
ADP + phosphorylated alpha-synuclein
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?
ATP + amyloid precursor protein
ADP + phosphorylated amyloid precursor protein
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?
ATP + axin
ADP + phosphorylated axin
ATP + beta-casein
ADP + beta-casein phosphate
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isoenzyme TPKII
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?
ATP + beta-catenin
ADP + beta-catenin phosphate
ATP + beta-catenin
ADP + phosphorylated beta-catenin
ATP + c-Jun
ADP + phosphorylated c-Jun
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substrate of isoform GSK-3alpha
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?
ATP + c-Myc
ADP + phosphorylated c-Myc
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?
ATP + cAMP response element-binding protein
ADP + phosphorylated cAMP response element-binding protein
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?
ATP + casein
ADP + phosphorylated casein
ATP + CCDC92
ADP + phosphorylated CCDC92
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?
ATP + CEP164
ADP + phospho-CEP164
ATP + CEP164
ADP + phosphorylated CEP164
TTBK2-induced phosphorylations of CEP164 modulate its function, which in turn seems relevant for the process of cilia formation
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?
ATP + CEP83
ADP + phosphorylated CEP83
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?
ATP + CEP89
ADP + phosphorylated CEP89
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?
ATP + CEP97
ADP + phospho-CEP97
ATP + coronavirus nucleocapsid protein
ADP + phosphorylated coronavirus nucleocapsid protein
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phosphorylation sites are at Ser177, Ser181, Ser184, Ser185, Ser187, Ser189, Ser191, Ser203, and Ser207
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?
ATP + cyclin D
ADP + phosphorylated cyclin D
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?
ATP + cyclin D1
ADP + phosphorylated cyclin D1
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?
ATP + cyclin E
ADP + phosphorylated cyclin E
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?
ATP + dephospho-beta-tubulin
ADP + beta-tubulin phosphate
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isoenzyme tau-tubulin kinase
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?
ATP + DIWKKFELLPTPPLSPSRRSG
ADP + DIWKKFELLP(P)TPPL(P)SPSRRSG
c-Myc
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?
ATP + DIWKKFELVPSPPTSPPWGL
ADP + DIWKKFELVP(P)SPPT(P)SPPWGL
L-myc
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?
ATP + DVL3
ADP + phosphorylated DVL3
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?
ATP + EEPQTVPEMPGETPPLSPIDMESQER
ADP + EEPQTVPEMPGE(P)TPPL(P)SPIDMESQER
c-Jun
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?
ATP + eIF2B peptide
ADP + phosphorylated eIF2B peptide
ATP + FITC-GSRSRTPSLP
ADP + FITC-GSRSRTP-phosphoserine-LP
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synthetic fluorescence-labeled peptide substrate derived from residues 207-216 of tau protein, phosphorylation of S214 by SGK1
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?
ATP + FXVEXTPXCFSRXSSLSSLS
ADP + ?
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?
ATP + glycogen synthase
ADP + glycogen synthase phosphate
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?
ATP + glycogen synthase
ADP + phosphorylated glycogen synthase
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?
ATP + H-Arg-Arg-Arg-Ala-Ala-Glu-Glu-Leu-Asp-Ser-Arg-Ala-Gly-pSer-Pro-Gln-Leu-OH
ADP + ?
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?
ATP + heat shock factor-1
ADP + phosphorylated heat shock factor-1
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?
ATP + histone H1
ADP + histone H1 phosphate
ATP + histone H2a
ADP + histone H2a phosphate
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isoenzyme TPKII
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?
ATP + histone H2b
ADP + histone H2b phosphate
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isoenzyme TPKII
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?
ATP + histone H3
ADP + histone H3 phosphate
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isoenzyme TPKII
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?
ATP + HLSNVSSTGSIDMVDSPQLATLADEVSASLAK
ADP + HLSNVSSTGSIDMVDpSPQLATLADEVSASLAK
ATP + HSPB6
ADP + phosphorylated HSPB6
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phosphorylation at Ser16
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?
ATP + JHMV-N protein
ADP + phosphorylated JHMV-N protein
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phosphorylation sites are at Ser197, Ser201, Ser-205, and Ser-209
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?
ATP + Jun
ADP + phosphorylated Jun
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?
ATP + KAUSSPTVSRKTD
ADP + KAUSSPTVSRKTD phosphate
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synthetic peptide p25/F3
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2.7.11.26 tau-protein kinase
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