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2.3.1.B43: protein-lysine desuccinylase (NAD+)

This is an abbreviated version!
For detailed information about protein-lysine desuccinylase (NAD+), go to the full flat file.

Word Map on EC 2.3.1.B43

Reaction

NAD+
+
[protein]-N6-acetyl-L-lysine
=
nicotinamide
+
[protein]-L-lysine
+
2'-O-acetyl-ADP-ribose

Synonyms

CobB, CobB Sir2 protein, histone desuccinylase, hSIRT5, hSIRT6, lysine desuccinylase, mitochondrial NAD+-dependent lysine deacylase, NAD+ dependent deacetylase, NAD+-dependent protein deacetylase, NAD+-dependent protein deacylase, NAD+-dependent sirtuin deacetylase, nicotinamide adenine dinucleotide-dependent protein deacetylase, Sir2Af1, SIRT5, SIRT5iso1, SIRT5iso2, SIRT5iso3, SIRT5iso4, sirtuin 5, sirtuin 5 deacylase, sirtuin 5 lysine deacylase, sirtuin deacylase, sirtuin-5, zSIRT5

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.B43 protein-lysine desuccinylase (NAD+)

Sequence

Sequence on EC 2.3.1.B43 - protein-lysine desuccinylase (NAD+)

Please use the AA Sequence and Transmembrane Helices Search for a specific query.
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
A0A1Y7VM56_MOUSE
350
0
38230
TrEMBL
-
NPD1_ARCFU
Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)
245
0
27143
Swiss-Prot
-
NPD_ECOLI
Escherichia coli (strain K12)
279
0
31464
Swiss-Prot
-
SIR5_RAT
310
0
34098
Swiss-Prot
Secretory Pathway (Reliability: 2)
SIR5_DANRE
305
0
33929
Swiss-Prot
-
SIR5_MOUSE
310
0
34134
Swiss-Prot
-
SIR5_HUMAN
310
0
33881
Swiss-Prot
-