Reference on EC 3.2.1.129 - endo-alpha-sialidase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kitajima, K.; Inoue, S.; Inoue, Y.; Troy, F.A.
Use of a bacteriophage-derived endo-N-acetylneuraminidase and an equine antipolysialyl antibody to characterize the polysialyl residues in salmonid fish egg polysialoglycoproteins. Substrate and immunospecificity studies
J. Biol. Chem.
263
18269-18276
1988
BRENDA: Escherichia phage K1F
Textmining: Equus caballus, salmonid fish, Oncorhynchus mykiss, Salvelinus namaycush
Pelkonen, S.; Pelkonen, J.; Finne, J.
Common cleavage pattern of polysialic acid by bacteriophage endosialidases of different properties and origins
J. Virol.
63
4409-4416
1989
bacteriophage PK1A, bacteriophage PK1E
Kwiatowski, B.; Boschek, B.; Thiele, H.; Stirm, S.
endo-N-Acetylneuraminidase associated with bacteriophage particles
J. Virol.
43
697-704
1982
BRENDA: bacteriophage phi1.2
Textmining: Bacteriophage sp.
Finne, J.; Mkel, P.H.
Cleavage of the polysialosyl units of brain glycoproteins by a bacteriophage endosialidase. Involvement of a long oligosaccharide segment in molecular interactions of polysialic acid
J. Biol. Chem.
260
1265-1270
1985
bacteriophage PK1A
Tomlinson, S.; Taylor, P.W.
Neuraminidase associated with coliphage E that specifically depolymerizes the Escherichia coli K1 capsular polysaccharide
J. Virol.
55
374-378
1985
Phage E
Hallenbeck, P.C.; Vimr, E.R.; Yu, F.; Bassler, B.; Troy, F.A.
Purification and properties of a bacteriophage-induced endo-N-acetylneuraminidase specific for poly-alpha-2,8-sialosyl carbohydrate units
J. Biol. Chem.
262
3553-3561
1987
Escherichia phage K1F
Vimr, E.R.; McCoy, R.D.; Vollger, H.F.; Wilkinson, N.C.; Troy, F.A.
Use of prokaryotic-derived probes to identify poly(sialic acid) in neonatal neuronal membranes
Proc. Natl. Acad. Sci. USA
81
1971-1975
1984
Escherichia phage K1F
Muhlenhoff, M.; Stummeyer, K.; Grove, M.; Sauerborn, M.; Gerardy-Schahn, R.
Proteolytic processing and oligomerization of bacteriophage-derived endosialidases
J. Biol. Chem.
278
12634-12644
2003
Escherichia phage K1F, Vectrevirus K1E
Long, G.S.; Bryant, J.M.; Taylor, P.W.; Luzio, J.P.
Complete nucleotide sequence of the gene encoding bacteriophage E endosialidase: implications for K1E endosialidase structure and function
Biochem. J.
309
543-550
1995
Vectrevirus K1E
Leggate, D.R.; Bryant, J.M.; Redpath, M.B.; Head, D.; Taylor, P.W.; Luzio, J.P.
Expression, mutagenesis and kinetic analysis of recombinant K1E endosialidase to define the site of proteolytic processing and requirements for catalysis
Mol. Microbiol.
44
749-760
2002
Vectrevirus K1E
Gerardy-Schahn, R.; Bethe, A.; Brennecke, T.; Muhlenhoff, M.; Eckhardt, M.; Ziesing, S.; Lottspeich, F.; Frosch, M.
Molecular cloning and functional expression of bacteriophage PK1E-encoded endoneuraminidase Endo NE
Mol. Microbiol.
16
441-450
1995
BRENDA: bacteriophage PK1E
Textmining: Bacteriophage sp., Bacteria, Escherichia coli
Stummeyer, K.; Dickmanns, A.; Mhlenhoff, M.; Gerardy-Schahn, R.; Ficner, R.
Crystal structure of the polysialic acid-degrading endosialidase of bacteriophage K1F
Nat. Struct. Mol. Biol.
12
90-96
2005
Escherichia phage K1F (Q04830), Escherichia phage K1F
Jakobsson, E.; Jokilammi, A.; Aalto, J.; Ollikka, P.; Lehtonen, J.V.; Hirvonen, H.; Finne, J.
Identification of amino acid residues at the active site of endosialidase that dissociate the polysialic acid binding and cleaving activities in Escherichia coli K1 bacteriophages
Biochem. J.
405
465-472
2007
Vectrevirus K1E, Enterobacteria phage K1A (A4UUQ0)
Haselhorst, T.; Stummeyer, K.; Muhlenhoff, M.; Schaper, W.; Gerardy-Schahn, R.; von Itzstein, M.
Endosialidase NF appears to bind polySia DP5 in a helical conformation
Chembiochem
7
1875-1877
2006
Bacteriophage sp.
Schwarzer, D.; Stummeyer, K.; Gerardy-Schahn, R.; Muehlenhoff, M.
Characterization of a Novel Intramolecular Chaperone Domain Conserved in Endosialidases and Other Bacteriophage Tail Spike and Fiber Proteins
J. Biol. Chem.
282
2821-2831
2007
Escherichia phage K1F
Berski, S.; van Bergeijk, J.; Schwarzer, D.; Stark, Y.; Kasper, C.; Scheper, T.; Grothe, C.; Gerardy-Schahn, R.; Kirschning, A.; Draeger, G.
Synthesis and biological evaluation of a polysialic acid-based hydrogel as enzymatically degradable scaffold material for tissue engineering
Biomacromolecules
9
2353-2359
2008
Escherichia phage K1F
Haile, Y.; Berski, S.; Draeger, G.; Nobre, A.; Stummeyer, K.; Gerardy-Schahn, R.; Grothe, C.
The effect of modified polysialic acid based hydrogels on the adhesion and viability of primary neurons and glial cells
Biomaterials
29
1880-1891
2008
Escherichia phage K1F
Murphy, J.A.; Hartwick, A.T.; Rutishauser, U.; Clarke, D.B.
Endogenous polysialylated neural cell adhesion molecule enhances the survival of retinal ganglion cells
Invest. Ophthalmol. Vis. Sci.
50
861-869
2009
Escherichia phage K1F
Schwarzer, D.; Stummeyer, K.; Haselhorst, T.; Freiberger, F.; Rode, B.; Grove, M.; Scheper, T.; von Itzstein, M.; Muehlenhoff, M.; Gerardy-Schahn, R.
Proteolytic release of the intramolecular chaperone domain confers processivity to endosialidase f
J. Biol. Chem.
284
9465-9474
2009
Escherichia phage K1F
Pekcec, A.; Fuest, C.; Muehlenhoff, M.; Gerardy-Schahn, R.; Potschka, H.
Targeting epileptogenesis-associated induction of neurogenesis by enzymatic depolysialylation of NCAM counteracts spatial learning dysfunction but fails to impact epilepsy development
J. Neurochem.
105
389-400
2008
BRENDA: Escherichia phage K1F
Textmining: Rattus
Schulz, E.C.; Neumann, P.; Gerardy-Schahn, R.; Sheldrick, G.M.; Ficner,R.
Structure analysis of endosialidase NF at 0.98 A resolution
Acta Crystallogr. Sect. D
66
176-180
2010
Escherichia phage K1F
Morley, T.J.; Willis, L.M.; Whitfield, C.; Wakarchuk, W.W.; Withers, S.G.
A new sialidase mechanism: bacteriophage K1F endo-sialidase is an inverting glycosidase
J. Biol. Chem.
284
17404-17410
2009
Escherichia phage K1F
Schulz, E.C.; Schwarzer, D.; Frank, M.; Stummeyer, K.; Muehlenhoff, M.; Dickmanns, A.; Gerardy-Schahn, R.; Ficner, R.
Structural basis for the recognition and cleavage of polysialic acid by the bacteriophage K1F tailspike protein endoNF
J. Mol. Biol.
397
341-351
2010
Escherichia phage K1F (Q04830)
Zelmer, A.; Martin, M.J.; Gundogdu, O.; Birchenough, G.; Lever, R.; Wren, B.W.; Luzio, J.P.; Taylor, P.W.
Administration of capsule-selective endosialidase E minimizes upregulation of organ gene expression induced by experimental systemic infection with Escherichia coli K1
Microbiology
156
2205-2215
2010
BRENDA: Escherichia coli, Escherichia coli A192PP
Textmining: Escherichia coli K1, Rattus
Chai, Y.; Xiong, H.; Ma, X.; Cheng, L.; Huang, G.; Zhang, Z.R.
Molecular characterization, structural analysis and determination of host range of a novel bacteriophage LSB-1
Virol. J.
7
255
2010
Phage LSB-1
Schwarzer, D.; Browning, C.; Stummeyer, K.; Oberbeck, A.; Muehlenhoff, M.; Gerardy-Schahn, R.; Leiman, P.G.
Structure and biochemical characterization of bacteriophage phi92 endosialidase
Virology
477
133-143
2015
Enterobacteria phage phi92 (I7HXG2)
Hsu, H.J.; Palka-Hamblin, H.; Bhide, G.P.; Myung, J.H.; Cheong, M.; Colley, K.J.; Hong, S.
Noncatalytic endosialidase enables surface capture of small-cell lung cancer cells utilizing strong dendrimer-mediated enzyme-glycoprotein interactions
Anal. Chem.
90
3670-3675
2018
Homo sapiens
Martin, N.T.; Wrede, C.; Niemann, J.; Brooks, J.; Schwarzer, D.; Kuehnel, F.; Gerardy-Schahn, R.
Targeting polysialic acid-abundant cancers using oncolytic adenoviruses with fibers fused to active bacteriophage borne endosialidase
Biomaterials
158
86-94
2018
Escherichia phage K1F (O04830), Escherichia phage K1F
Li, C.; Zhang, Y.X.; Yang, C.; Hao, F.; Chen, S.S.; Hao, Q.; Lu, T.; Qu, T.Y.; Zhao, L.R.; Duan, W.M.
Intraventricular administration of endoneuraminidase-N facilitates ectopic migration of subventricular zone-derived neural progenitor cells into 6-OHDA lesioned striatum of mice
Exp. Neurol.
277
139-149
2016
BRENDA: Mus musculus
Textmining: Mus sp.
Gebhart, D.; Williams, S.R.; Scholl, D.
Bacteriophage SP6 encodes a second tailspike protein that recognizes Salmonella enterica serogroups C2 and C3
Virology
507
263-266
2017
Zindervirus SP6
McCoy, R.; Vimr, E.; Troy, F.
CMP-NeuNAc poly-alpha-2,8-sialosyl sialyltransferase and the biosynthesis of polysialosyl units in neural cell adhesion molecules
J. Biol. Chem.
260
12695-12699
1985
Rattus
Mushtaq, N; Redpath, MB; Luzio, JP; Taylor, PW
Treatment of experimental Escherichia coli infection with recombinant bacteriophage-derived capsule depolymerase.
J Antimicrob Chemother
56
160-5
2005
Rattus, Escherichia coli K1
Vionnet, J; Vann, WF
Successive glycosyltransfer of sialic acid by Escherichia coli K92 polysialyltransferase in elongation of oligosialic acceptors.
Glycobiology
17
735-43
2007
Escherichia coli, Neisseria meningitidis
James, WM; Agnew, WS
Multiple oligosaccharide chains in the voltage-sensitive Na channel from electrophorus electricus: evidence for alpha-2,8-linked polysialic acid.
Biochem Biophys Res Commun
148
817-26
1987
Electrophorus electricus
El Maarouf, A; Kolesnikov, Y; Pasternak, G; Rutishauser, U
Removal of polysialylated neural cell adhesion molecule increases morphine analgesia and interferes with tolerance in mice.
Brain Res
1404
55-62
2011
Mus sp.
Mushtaq, N; Redpath, MB; Luzio, JP; Taylor, PW
Prevention and cure of systemic Escherichia coli K1 infection by modification of the bacterial phenotype.
Antimicrob Agents Chemother
48
1503-8
2004
Escherichia coli
Daniel, L; Durbec, P; Gautherot, E; Rouvier, E; Rougon, G; Figarella-Branger, D
A nude mice model of human rhabdomyosarcoma lung metastases for evaluating the role of polysialic acids in the metastatic process.
Oncogene
20
997-1004
2001
Metazoa, Homo sapiens, Mus musculus, Mus sp.
Lopez-Fernandez, MA; Montaron, MF; Varea, E; Rougon, G; Venero, C; Abrous, DN; Sandi, C
Upregulation of polysialylated neural cell adhesion molecule in the dorsal hippocampus after contextual fear conditioning is involved in long-term memory formation.
J Neurosci
27
4552-61
2007
Hippocampus, Metazoa
Burgess, A; Wainwright, SR; Shihabuddin, LS; Rutishauser, U; Seki, T; Aubert, I
Polysialic acid regulates the clustering, migration, and neuronal differentiation of progenitor cells in the adult hippocampus.
Dev Neurobiol
68
1580-90
2008
Hippocampus, Rattus, Metazoa
Black, MA; Deurveilher, S; Seki, T; Marsh, DR; Rutishauser, U; Rafuse, VF; Semba, K
Role of polysialylated neural cell adhesion molecule in rapid eye movement sleep regulation in rats.
Eur J Neurosci
30
2190-204
2009
Rattus
Gundelach, J; Koch, M
EndoN treatment allows neuroblasts to leave the rostral migratory stream and migrate towards a lesion within the prefrontal cortex of rats.
Neural Regen Res
15
1740-1747
2020
Rattus
Prosser, RA; Rutishauser, U; Ungers, G; Fedorkova, L; Glass, JD
Intrinsic role of polysialylated neural cell adhesion molecule in photic phase resetting of the Mammalian circadian clock.
J Neurosci
23
652-8
2003
Rattus
Angata, K; Long, JM; Bukalo, O; Lee, W; Dityatev, A; Wynshaw-Boris, A; Schachner, M; Fukuda, M; Marth, JD
Sialyltransferase ST8Sia-II assembles a subset of polysialic acid that directs hippocampal axonal targeting and promotes fear behavior.
J Biol Chem
279
32603-13
2004
Mus musculus
Yamamoto, N; Inui, K; Matsuyama, Y; Harada, A; Hanamura, K; Murakami, F; Ruthazer, ES; Rutishauser, U; Seki, T
Inhibitory mechanism by polysialic acid for lamina-specific branch formation of thalamocortical axons.
J Neurosci
20
9145-51
2000
Rattus
Kumar, S; Parkash, J; Kataria, H; Kaur, G
Enzymatic removal of polysialic acid from neural cell adhesion molecule interrupts gonadotropin releasing hormone (GnRH) neuron-glial remodeling.
Mol Cell Endocrinol
2011
Rattus
Lobanovskaya, N; Zharkovsky, T; Jaako, K; Jrgenson, M; Aonurm-Helm, A; Zharkovsky, A
PSA modification of NCAM supports the survival of injured retinal ganglion cells in adulthood.
Brain Res
1625
9-17
2015
Mus musculus, Mus sp., Metazoa
Petridis, AK; El-Maarouf, A; Rutishauser, U
Polysialic acid regulates cell contact-dependent neuronal differentiation of progenitor cells from the subventricular zone.
Dev Dyn
230
675-84
2004
Mus musculus
Garcia-Segura, LM; Cañas, B; Parducz, A; Rougon, G; Theodosis, D; Naftolin, F; Torres-Aleman, I
Estradiol promotion of changes in the morphology of astroglia growing in culture depends on the expression of polysialic acid of neural membranes.
Glia
13
209-16
1995
Rattus, Metazoa
Wang, C; Rougon, G; Kiss, JZ
Requirement of polysialic acid for the migration of the O-2A glial progenitor cell from neurohypophyseal explants.
J Neurosci
14
4446-57
1994
Enterobacteria phage K1
Daston, MM; Bastmeyer, M; Rutishauser, U; O'Leary, DD
Spatially restricted increase in polysialic acid enhances corticospinal axon branching related to target recognition and innervation.
J Neurosci
16
5488-97
1996
Rattus, Electron
Muller, D; Wang, C; Skibo, G; Toni, N; Cremer, H; Calaora, V; Rougon, G; Kiss, JZ
PSA-NCAM is required for activity-induced synaptic plasticity.
Neuron
17
413-22
1996
Mus musculus
Yoshida, K; Rutishauser, U; Crandall, JE; Schwarting, GA
Polysialic acid facilitates migration of luteinizing hormone-releasing hormone neurons on vomeronasal axons.
J Neurosci
19
794-801
1999
Mus musculus, Mus sp.
Theodosis, DT; Bonhomme, R; Vitiello, S; Rougon, G; Poulain, DA
Cell surface expression of polysialic acid on NCAM is a prerequisite for activity-dependent morphological neuronal and glial plasticity.
J Neurosci
19
10228-36
1999
Rattus, Electron
Monnier, PP; Beck, SG; Bolz, J; Henke-Fahle, S
The polysialic acid moiety of the neural cell adhesion molecule is involved in intraretinal guidance of retinal ganglion cell axons.
Dev Biol
229
1-14
2001
Gallus gallus, Areas
Hoyk, Z; Parducz, A; Theodosis, DT
The highly sialylated isoform of the neural cell adhesion molecule is required for estradiol-induced morphological synaptic plasticity in the adult arcuate nucleus.
Eur J Neurosci
13
649-56
2001
Rattus
Catheline, G; Touquet, B; Lombard, MC; Poulain, DA; Theodosis, DT
A study of the role of neuro-glial remodeling in the oxytocin system at lactation.
Neuroscience
137
309-16
2006
Rattus
Venero, C; Herrero, AI; Touyarot, K; Cambon, K; López-Fernández, MA; Berezin, V; Bock, E; Sandi, C
Hippocampal up-regulation of NCAM expression and polysialylation plays a key role on spatial memory.
Eur J Neurosci
23
1585-1595
2006
Rattus
Duveau, V; Fritschy, JM
PSA-NCAM-dependent GDNF signaling limits neurodegeneration and epileptogenesis in temporal lobe epilepsy.
Eur J Neurosci
32
89-98
2010
Mus sp., Mus musculus, Hippocampus
Li, X; Monckton, EA; Godbout, R
Ectopic expression of transcription factor AP-2? in developing retina: effect on PSA-NCAM and axon routing.
J Neurochem
129
72-84
2014
Spondias purpurea
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