Cloned (Comment) | Organism |
---|---|
- |
Vectrevirus K1E |
mutant proteins harbouring single amino acid substitutions expressed as GFP-fusion proteins | Enterobacteria phage K1A |
Protein Variants | Comment | Organism |
---|---|---|
D489N | back-mutations, partial reduction of enzymic activity. Single amino acid substitution do not inactivate the catalytic activity totally | Enterobacteria phage K1A |
H332N/N489D | complete inactivation | Enterobacteria phage K1A |
H417Y/N489D | complete inactivation | Enterobacteria phage K1A |
additional information | N-terminal deletion mutants are catalytically active, whereas all C-terminally truncated mutants are inactive | Enterobacteria phage K1A |
additional information | point mutation located on or near the putative active site, exhibits greatly reduced activity | Vectrevirus K1E |
R614G | displays full endosialidase activity | Vectrevirus K1E |
R614G | displays full endosialidase activity | Enterobacteria phage K1A |
Y417H | back-mutations, partial reduction of enzymic activity. Single amino acid substitution do not inactivate the catalytic activity totally | Enterobacteria phage K1A |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
76000 | - |
- |
Enterobacteria phage K1A |
89000 | - |
sequence analysis | Enterobacteria phage K1A |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Enterobacteria phage K1A | A4UUQ0 | - |
- |
Vectrevirus K1E | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
poly(sialic) acid + H2O | - |
Vectrevirus K1E | ? | - |
? | |
poly(sialic) acid + H2O | - |
Enterobacteria phage K1A | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | - |
Enterobacteria phage K1A |
Synonyms | Comment | Organism |
---|---|---|
endo-N-acetylneuraminidase | - |
Vectrevirus K1E |
endo-N-acetylneuraminidase | - |
Enterobacteria phage K1A |
endosialidase | - |
Vectrevirus K1E |
endosialidase | - |
Enterobacteria phage K1A |