Reference on EC 2.7.11.17 - Ca2+/calmodulin-dependent protein kinase and Organism(s) Homo sapiens and UniProt Accession Q13555
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Boeckmann, B.; Bairoch, A.; Apweiler, R.; Blatter, M.C.; Estreicher, A.; Gasteiger, E.; Martin M.J.; Michoud, K.; O'Donovan, C.; Phan, I.; Pilbout, S.; Schneider, M.
The SWISS-PROT protein knowledgebase and its supplement TrEMBL
Nucleic Acids Res.
31
365-370
2003
Homo sapiens (Q13554), Homo sapiens (Q9UQM7), Metarhizium anisopliae (O14408), Mus musculus (Q923T9)
Rochlitz, H.; Voigt, A.; Lankat-Buttgereit, B.; Goke, B.; Heimberg, H.; Nauck, M.A.; Schiemann, U.; Schatz, H.; Pfeiffer, A.F.
Cloning and quantitative determination of the human Ca2+/calmodulin-dependent protein kinase II (CaMK II) isoforms in human beta cells
Diabetologia
43
465-473
2000
Homo sapiens (Q13554), Homo sapiens
Tombes, R.M.; Krystal, G.W.
Identification of novel human tumor cell-specific CaMK-II variants
Biochim. Biophys. Acta
1355
281-292
1997
Homo sapiens (Q13554), Homo sapiens (Q13557)
Wang, P.; Wu, Y.L.; Zhou, T.H.; Sun, Y.; Pei, G.
Identification of alternative splicing variants of the beta subunit of human Ca(2+)/calmodulin-dependent protein kinase II with different activities
FEBS Lett.
475
107-110
2000
Homo sapiens (Q13554)
Hoch, B.; Meyer, R.; Hetzer, R.; Krause, E.G.; Karczewski, P.
Identification and expression of delta-isoforms of the multifunctional Ca2+/calmodulin-dependent protein kinase in failing and nonfailing human myocardium
Circ. Res.
84
713-721
1999
Homo sapiens (Q13557), Homo sapiens
Haribabu, B.; Hook, S.S.; Selbert, M.A.; Goldstein, E.G.; Tomhave, E.D.; Edelman, A.M.; Snyderman, R.; Means, A.R.
Human calcium-calmodulin dependent protein kinase I: cDNA cloning, domain structure and activation by phosphorylation at threonine-177 by calcium-calmodulin dependent protein kinase I kinase
EMBO J.
14
3679-3686
1995
Homo sapiens (Q14012), Homo sapiens
Bland, M.M.; Monroe, R.S.; Ohmstede, C.A.
The cDNA sequence and characterization of the Ca2+/calmodulin-dependent protein kinase-Gr from human brain and thymus
Gene
142
191-197
1994
Homo sapiens (Q16566), Homo sapiens
Kitani, T.; Okuno, S.; Fujisawa, H.
cDNA cloning and expression of human calmodulin-dependent protein kinase IV
J. Biochem.
115
637-640
1994
Homo sapiens (Q16566), Homo sapiens
Mosialos, G.; Hanissian, S.H.; Jawahar, S.; Vara, L.; Kieff, E.; Chatila, T.A.
A Ca2+/calmodulin-dependent protein kinase, CaM kinase-Gr, expressed after transformation of primary human B lymphocytes by Epstein-Barr virus (EBV) is induced by the EBV oncogene LMP1
J. Virol.
68
1697-1705
1994
Homo sapiens (Q16566), Homo sapiens
Rodriguez-Mora, O.G.; LaHair, M.M.; McCubrey, J.A.; Franklin, R.A.
Calcium/calmodulin-dependent kinase I and calcium/calmodulin-dependent kinase kinase participate in the control of cell cycle progression in MCF-7 human breast cancer cells
Cancer Res.
65
5408-5416
2005
Homo sapiens (Q14012), Homo sapiens
Zhang, T.; Brown, J.H.
Role of Ca2+/calmodulin-dependent protein kinase II in cardiac hypertrophy and heart failure
Cardiovasc. Res.
63
476-486
2004
Oryctolagus cuniculus, Homo sapiens, Mus musculus, Rattus norvegicus, Sus scrofa
Pan, F.; Means, A.R.; Liu, J.O.
Calmodulin-dependent protein kinase IV regulates nuclear export of Cabin1 during T-cell activation
EMBO J.
24
2104-2113
2005
Homo sapiens
Rodriguez-Mora, O.; LaHair, M.M.; Howe, C.J.; McCubrey, J.A.; Franklin, R.A.
Calcium/calmodulin-dependent protein kinases as potential targets in cancer therapy
Expert Opin. Ther. Targets
9
791-808
2005
Homo sapiens, Mus musculus, Rattus norvegicus
Ishikawa, Y.; Tokumitsu, H.; Inuzuka, H.; Murata-Hori, M.; Hosoya, H.; Kobayashi, R.
Identification and characterization of novel components of a Ca2+/calmodulin-dependent protein kinase cascade in HeLa cells
FEBS Lett.
550
57-63
2003
Homo sapiens (Q8IU85)
Takemoto-Kimura, S.; Terai, H.; Takamoto, M.; Ohmae, S.; Kikumura, S.; Segi, E.; Arakawa, Y.; Furuyashiki, T.; Narumiya, S.; Bito, H.
Molecular cloning and characterization of CLICK-III/CaMKIg, a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase (CaMK)
J. Biol. Chem.
278
18597-18605
2003
Rattus norvegicus, Mus musculus (Q91VB2), Homo sapiens (Q96NX5)
Chow, F.A.; Anderson, K.A.; Noeldner, P.K.; Means, A.R.
The autonomous activity of calcium/calmodulin-dependent protein kinase IV is required for its role in transcription
J. Biol. Chem.
280
20530-20538
2005
Homo sapiens
Tsui, J.; Inagaki, M.; Schulman, H.
Calcium/calmodulin-dependent protein kinase II (CaMKII) localization acts in concert with substrate targeting to create spatial restriction for phosphorylation
J. Biol. Chem.
280
9210-9216
2005
Homo sapiens
Yamamoto, H.; Hiragami, Y.; Murayama, M.; Ishizuka, K.; Kawahara, M.; Takashima, A.
Phosphorylation of tau at serine 416 by Ca2+/calmodulin-dependent protein kinase II in neuronal soma in brain
J. Neurochem.
94
1438-1447
2005
Homo sapiens, Rattus norvegicus
Li, H.; Aluko, R.E.
Kinetics of the inhibition of calcium/calmodulin-dependent protein kinase II by pea protein-derived peptides
J. Nutr. Biochem.
16
656-662
2005
Homo sapiens
Maier, L.S.; Bers, D.M.
Role of Ca2+/calmodulin-dependent protein kinase (CaMK) in excitation-contraction coupling in the heart
Cardiovasc. Res.
73
631-640
2007
Oryctolagus cuniculus, Homo sapiens, Mus musculus
Tsui, J.; Malenka, R.C.
Substrate localization creates specificity in calcium/calmodulin-dependent protein kinase II signaling at synapses
J. Biol. Chem.
281
13794-13804
2006
Homo sapiens
Ishiguro, K.; Green, T.; Rapley, J.; Wachtel, H.; Giallourakis, C.; Landry, A.; Cao, Z.; Lu, N.; Takafumi, A.; Goto, H.; Daly, M.J.; Xavier, R.J.
Ca2+/calmodulin-dependent protein kinase II is a modulator of CARMA1-mediated NF-kappaB activation
Mol. Cell. Biol.
26
5497-5508
2006
Homo sapiens
Ishida, A.; Sueyoshi, N.; Shigeri, Y.; Kameshita, I.
Negative regulation of multifunctional Ca2+/calmodulin-dependent protein kinases: physiological and pharmacological significance of protein phosphatases
Br. J. Pharmacol.
154
729-740
2008
Homo sapiens, Homo sapiens (Q14012), Homo sapiens (Q16566)
Si, J.; Collins, S.J.
Activated Ca2+/calmodulin-dependent protein kinase IIgamma is a critical regulator of myeloid leukemia cell proliferation
Cancer Res.
68
3733-3742
2008
Homo sapiens (Q13555)
Shimizu, M.; Nakamura, H.; Hirabayashi, T.; Suganami, A.; Tamura, Y.; Murayama, T.
Ser515 phosphorylation-independent regulation of cytosolic phospholipase A2alpha (cPLA2alpha) by calmodulin-dependent protein kinase: possible interaction with catalytic domain A of cPLA2alpha
Cell. Signal.
20
815-824
2008
Homo sapiens
Bossuyt, J.; Helmstadter, K.; Wu, X.; Clements-Jewery, H.; Haworth, R.S.; Avkiran, M.; Martin, J.L.; Pogwizd, S.M.; Bers, D.M.
Ca2+/calmodulin-dependent protein kinase IIdelta and protein kinase D overexpression reinforce the histone deacetylase 5 redistribution in heart failure
Circ. Res.
102
695-702
2008
Oryctolagus cuniculus (O77708), Oryctolagus cuniculus, Homo sapiens (Q13557), Homo sapiens
Matsumoto, K.; Murao, K.; Imachi, H.; Nishiuchi, T.; Cao, W.; Yu, X.; Li, J.; Ahmed, R.A.; Iwama, H.; Kobayashi, R.; Tokumitsu, H.; Ishida, T.
The role of calcium/calmodulin-dependent protein kinase cascade on MIP-1alpha gene expression of ATL cells
Exp. Hematol.
36
390-400
2008
Homo sapiens (Q16566), Homo sapiens
Masaoka, T.; Nishi, M.; Ryo, A.; Endo, Y.; Sawasaki, T.
The wheat germ cell-free based screening of protein substrates of calcium/calmodulin-dependent protein kinase II delta
FEBS Lett.
582
1795-1801
2008
Homo sapiens (Q13557), Homo sapiens
Wang, Y.; Tandan, S.; Cheng, J.; Yang, C.; Nguyen, L.; Sugianto, J.; Johnstone, J.L.; Sun, Y.; Hill, J.A.
Ca2+/calmodulin-dependent protein kinase II-dependent remodeling of Ca2+ current in pressure overload heart failure
J. Biol. Chem.
283
25524-25532
2008
Homo sapiens
Suzuki, T.; Du, F.; Tian, Q.B.; Zhang, J.; Endo, S.
Ca2+/calmodulin-dependent protein kinase IIalpha clusters are associated with stable lipid rafts and their formation traps PSD-95
J. Neurochem.
104
596-610
2008
Homo sapiens
Jiang, X.; Lautermilch, N.J.; Watari, H.; Westenbroek, R.E.; Scheuer, T.; Catterall, W.A.
Modulation of CaV2.1 channels by Ca2+/calmodulin-dependent protein kinase II bound to the C-terminal domain
Proc. Natl. Acad. Sci. USA
105
341-346
2008
Homo sapiens
Monteiro, P.; Gilot, D.; Langouet, S.; Fardel, O.
Activation of the aryl hydrocarbon receptor by the calcium/calmodulin-dependent protein kinase kinase inhibitor 7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid (STO-609)
Drug Metab. Dispos.
36
2556-2563
2008
Homo sapiens
Huynh, Q.K.; Pagratis, N.
Kinetic mechanisms of Ca++/calmodulin dependent protein kinases
Arch. Biochem. Biophys.
506
130-136
2011
Homo sapiens (Q13554), Homo sapiens (Q13555), Homo sapiens (Q13557), Homo sapiens (Q9UQM7)
Hoffman, L.; Farley, M.M.; Waxham, M.N.
Calcium-calmodulin-dependent protein kinase II isoforms differentially impact the dynamics and structure of the actin cytoskeleton
Biochemistry
52
1198-1207
2013
Rattus norvegicus (P08413), Rattus norvegicus (P11275), Homo sapiens (Q13555), Homo sapiens (Q13557)
Kukimoto-Niino, M.; Yoshikawa, S.; Takagi, T.; Ohsawa, N.; Tomabechi, Y.; Terada, T.; Shirouzu, M.; Suzuki, A.; Lee, S.; Yamauchi, T.; Okada-Iwabu, M.; Iwabu, M.; Kadowaki, T.; Minokoshi, Y.; Yokoyama, S.
Crystal structure of the Ca2+/calmodulin-dependent protein kinase kinase in complex with the inhibitor STO-609
J. Biol. Chem.
286
22570-22579
2011
Homo sapiens (Q96RR4), Homo sapiens
Pandey, D.; Gratton, J.P.; Rafikov, R.; Black, S.M.; Fulton, D.J.
Calcium/calmodulin-dependent kinase II mediates the phosphorylation and activation of NADPH oxidase 5
Mol. Pharmacol.
80
407-415
2011
Homo sapiens
Naz, H.; Shahbaaz, M.; Bisetty, K.; Islam, A.; Ahmad, F.; Hassan, M.I.
Effect of pH on the structure, function, and stability of human calcium/calmodulin-dependent protein kinase IV: combined spectroscopic and MD simulation studies
Biochem. Cell Biol.
94
221-228
2016
Homo sapiens (Q16566), Homo sapiens
Naz, H.; Jameel, E.; Hoda, N.; Shandilya, A.; Khan, P.; Islam, A.; Ahmad, F.; Jayaram, B.; Hassan, M.I.
Structure guided design of potential inhibitors of human calcium-calmodulin dependent protein kinase IV containing pyrimidine scaffold
Bioorg. Med. Chem. Lett.
26
782-788
2016
Homo sapiens
Nafzger, S.; Rougier, J.S.
Calcium/calmodulin-dependent serine protein kinase CASK modulates the L-type calcium current
Cell Calcium
61
10-21
2016
Homo sapiens
Fischer, T.H.; Herting, J.; Tirilomis, T.; Renner, A.; Neef, S.; Toischer, K.; Ellenberger, D.; Foerster, A.; Schmitto, J.D.; Gummert, J.; Schoendube, F.A.; Hasenfuss, G.; Maier, L.S.; Sossalla, S.
Ca2+/calmodulin-dependent protein kinase II and protein kinase A differentially regulate sarcoplasmic reticulum Ca2+ leak in human cardiac pathology
Circulation
128
970-981
2013
Homo sapiens
Magupalli, V.; Mochida, S.; Yan, J.; Jiang, X.; Westenbroek, R.; Nairn, A.; Scheuer, T.; Catterall, W.
Ca2+-independent activation of Ca2+/Calmodulin-dependent protein kinase II bound to the C-terminal domain of CaV2.1 calcium channels
J. Biol. Chem.
288
4637-4648
2013
Homo sapiens
Madhavan, M.; Mohanan, A.G.; Jacob, R.S.; Gunasekaran, S.; Nair, R.R.; Omkumar, R.V.
Glu60 of alpha-calcium/calmodulin dependent protein kinase II mediates crosstalk between the regulatory T-site and protein substrate binding region of the active site
Arch. Biochem. Biophys.
685
108348
2020
Homo sapiens
Rong, J.; Pool, B.; Zhu, M.; Munro, J.; Cornish, J.; McCarthy, G.M.; Dalbeth, N.; Poulsen, R.
Basic calcium phosphate crystals induce osteoarthritis-associated changes in phenotype markers in primary human chondrocytes by a calcium/calmodulin kinase 2-dependent mechanism
Calcif. Tissue Int.
104
331-343
2019
Homo sapiens
Jameel, E.; Naz, H.; Khan, P.; Tarique, M.; Kumar, J.; Mumtazuddin, S.; Ahamad, S.; Islam, A.; Ahmad, F.; Hoda, N.; Hassan, M.
Design, synthesis, and biological evaluation of pyrimidine derivatives as potential inhibitors of human calcium/calmodulin-dependent protein kinase IV
Chem. Biol. Drug Des.
89
741-754
2017
Homo sapiens (Q16566), Homo sapiens
Gocher, A.; Azabdaftari, G.; Euscher, L.; Dai, S.; Karacosta, L.; Franke, T.; Edelman, A.
Akt activation by Ca2+/calmodulin-dependent protein kinase kinase 2 (CaMKK2) in ovarian cancer cells
J. Biol. Chem.
292
14188-14204
2017
Homo sapiens (Q96RR4)
Hoda, N.; Naz, H.; Jameel, E.; Shandilya, A.; Dey, S.; Hassan, M.; Ahmad, F.; Jayaram, B.
Curcumin specifically binds to the human calcium-calmodulin-dependent protein kinase IV Fluorescence and molecular dynamics simulation studies
J. Biomol. Struct. Dyn.
34
572-584
2016
Homo sapiens (Q16566), Homo sapiens
