Literature summary for 2.7.11.17 extracted from

Jiang, X.; Lautermilch, N.J.; Watari, H.; Westenbroek, R.E.; Scheuer, T.; Catterall, W.A.
Modulation of CaV2.1 channels by Ca2+/calmodulin-dependent protein kinase II bound to the C-terminal domain (2008), Proc. Natl. Acad. Sci. USA, 105, 341-346.

Search for more literature for 2.7.11.17

Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	CaMKII binds and enhances the activity of voltage-gated calcium 2.1 channels, but the modulation is not caused by phosphorylation	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
autocamtide-2 related inhibitory peptide	-	Homo sapiens
CaM-KIIN	noncompetitive inhibitor	Homo sapiens
KN-93	-	Homo sapiens

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Ca2+	dependent on	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	CaMKII regulates P/Q-type Ca2+ current in neurons	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
tsA-201 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	CaMKII regulates P/Q-type Ca2+ current in neurons	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
calcium/calmodulin-dependent protein kinase II	-	Homo sapiens
CaMKII	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Homo sapiens
Calmodulin	dependent on	Homo sapiens

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Release 2023.1 (January 2023)