Reference on EC 2.7.11.13 - protein kinase C and Organism(s) Homo sapiens and UniProt Accession P05129
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kemp, B.E.; Pearson, R.B.; House, M.
Pseudosubstrate-based peptide inhibitors
Methods Enzymol.
201
287-304
1991
Saccharomyces cerevisiae, Drosophila melanogaster, eukaryota, Homo sapiens
Sturany, S.; Van Lint, J.; Muller, F.; Wilda, M.; Hameister, H.; Hocker, M.; Brey, A.; Gern, U.; Vandenheede, J.; Gress, T.; Adler, G.; Seufferlein, T.
Molecular cloning and characterization of the human protein kinase D2. A novel member of the protein kinase D family of serine threonine kinases
J. Biol. Chem.
276
3310-3318
2001
Homo sapiens (Q9BZL6), Homo sapiens
Zhang, Q.H.; Ye, M.; Wu, X.Y.; et al.
Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells
Genome Res.
10
1546-1560
2000
Homo sapiens (Q9BZL6)
Hayashi, A.; Seki, N.; Hattori, A.; Kozuma, S.; Saito, T.
PKCnu, a new member of the protein kinase C family, composes a fourth subfamily with PKCmu
Biochim. Biophys. Acta
1450
99-106
1999
Homo sapiens (O94806), Homo sapiens
Coussens, L.; Parker, P.J.; Rhee, L.; Yang-Feng, T.L.; Chen, E.; Waterfield, M.D.; Francke, U.; Ullrich, A.
Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways
Science
233
859-866
1986
Bos taurus (P05126), Bos taurus, Homo sapiens (P05129), Homo sapiens
Dryja, T.P.; McEvoy, J.; McGee, T.L.; Berson, E.L.
No mutations in the coding region of the PRKCG gene in three families with retinitis pigmentosa linked to the RP11 locus on chromosome 19q
Am. J. Hum. Genet.
65
926-928
1999
Homo sapiens (P05129)
Al-Maghtheh, M.; Vithana, E.N.; Inglehearn, C.F.; Moore, T.; Bird, A.C.; Bhattacharya, S.S.
Segregation of a PRKCG mutation in two RP11 families
Am. J. Hum. Genet.
62
1248-1252
1998
Homo sapiens (P05129)
Kochs, G.; Hummel, R.; Meyer, D.; Hug, H.; Marme, D.; Sarre, T.F.
Activation and substrate specificity of the human protein kinase C alpha and zeta isoenzymes
Eur. J. Biochem.
216
597-606
1993
Homo sapiens (P05129), Homo sapiens (Q05513), Homo sapiens
Loftus, B.J.; Kim, U.J.; Sneddon, V.P.; Kalush, F.; Brandon, R.; Fuhrmann, J.; Mason, T.; Crosby, M.L.; Barnstead, M.; Cronin, L.; Deslattes Mays, A.; Cao, Y.; Xu, R.X.; Kang, H.L.; Mitchell, S.; Eichler, E.E.; Harris, P.C.; Venter, J.C.; Adams, M.D.
Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q
Genomics
60
295-308
1999
Homo sapiens (P05771)
Mahajna, J.; King, P.; Parker, P.; Haley, J.
Autoregulation of cloned human protein kinase C beta and gamma gene promoters in U937 cells
DNA Cell Biol.
14
213-222
1995
Homo sapiens (P05771), Homo sapiens
Obeid, L.M.; Blobe, G.C.; Karolak, L.A.; Hannun, Y.A.
Cloning and characterization of the major promoter of the human protein kinase C beta gene. Regulation by phorbol esters
J. Biol. Chem.
267
20804-20810
1992
Homo sapiens (P05771), Homo sapiens
Kubo, K.; Ohno, S.; Suzuki, K.
Nucleotide sequence of the 3' portion of a human gene for protein kinase C beta I/beta II
Nucleic Acids Res.
15
7179-7180
1987
Homo sapiens (P05771), Homo sapiens
Kubo, K.; Ohno, S.; Suzuki, K.
Primary structures of human protein kinase C beta I and beta II differ only in their C-terminal sequences
FEBS Lett.
223
138-142
1987
Homo sapiens (P05771), Homo sapiens
Coussens, L.; Rhee, L.; Parker, P.J.; Ullrich, A.
Alternative splicing increases the diversity of the human protein kinase C family
DNA
6
389-394
1987
Homo sapiens (P05771), Homo sapiens
McSwine-Kennick, R.L.; McKeegan, E.M.; Johnson, M.D.; Morin, M.J.
Phorbol diester-induced alterations in the expression of protein kinase C isozymes and their mRNAs. Analysis in wild-type and phorbol diester-resistant HL-60 cell clones
J. Biol. Chem.
266
15135-15143
1991
Homo sapiens (P17252)
Finkenzeller, G.; Marme, D.; Hug, H.
Sequence of human protein kinase C alpha
Nucleic Acids Res.
18
2183
1990
Homo sapiens (P17252), Homo sapiens
Palmer, R.H.; Ridden, J.; Parker, P.J.
Identification of multiple, novel, protein kinase C-related gene products
FEBS Lett.
356
5-8
1994
Homo sapiens (P24723), Homo sapiens (Q16512), Homo sapiens (Q16513)
Bacher, N.; Zisman, Y.; Berent, E.; Livneh, E.
Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart
Mol. Cell. Biol.
12
1404
1992
Homo sapiens (P24723)
Bacher, N.; Zisman, Y.; Berent, E.; Livneh, E.
Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart
Mol. Cell. Biol.
11
126-133
1991
Homo sapiens (P24723), Homo sapiens
Mazzarella, R.; Ciccodicola, A.; Esposito, T.; Arcucci, A.; Migliaccio, C.; Jones, C.; Schlessinger, D.; D'Urso, M.; D'Esposito, M.
Human protein kinase C iota gene (PRKCI) is closely linked to the BTK gene in Xq21.3
Genomics
26
629-631
1995
Homo sapiens (P41743), Homo sapiens
Selbie, L.A.; Schmitz-Peiffer, C.; Sheng, Y.; Biden, T.J.
Molecular cloning and characterization of PKC iota, an atypical isoform of protein kinase C derived from insulin-secreting cells
J. Biol. Chem.
268
24296-24302
1993
Homo sapiens (P41743), Homo sapiens
Basta, P.; Strickland, M.B.; Holmes, W.; Loomis, C.R.; Ballas, L.M.; Burns, D.J.
Sequence and expression of human protein kinase C-epsilon
Biochim. Biophys. Acta
1132
154-160
1992
Homo sapiens (Q02156), Homo sapiens
Chang, J.D.; Xu, Y.; Raychowdhury, M.K.; Ware, J.A.
Molecular cloning and expression of a cDNA encoding a novel isoenzyme of protein kinase C (nPKC). A new member of the nPKC family expressed in skeletal muscle, megakaryoblastic cells, and platelets
J. Biol. Chem.
268
14208-14214
1993
Homo sapiens (Q04759), Homo sapiens
Baier, G.; Telford, D.; Giampa, L.; Coggeshall, K.M.; Baier-Bitterlich, G.; Isakov, N.; Altman, A.
Molecular cloning and characterization of PKC theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells
J. Biol. Chem.
268
4997-5004
1993
Homo sapiens (Q04759), Homo sapiens
Barbee, J.L.; Deutscher, S.L.; Loomis, C.R.; Burns, D.J.
The cDNA sequence encoding human protein kinase C-zeta
Gene
132
305-306
1993
Homo sapiens (Q05513), Homo sapiens
Nomoto, S.; Watanabe, Y.; Ninomiya-Tsuji, J.; Yang, L.X.; Nagai, Y.; Kiuchi, K.; Hagiwara, M.; Hidaka, H.; Matsumoto, K.; Irie, K.
Functional analyses of mammalian protein kinase C isozymes in budding yeast and mammalian fibroblasts
Genes Cells
2
601-614
1997
Homo sapiens (Q05655), Homo sapiens
Aris, J.P.; Basta, P.V.; Holmes, W.D.; Ballas, L.M.; Moomaw, C.; Rankl, N.B.; Blobel, G.; Loomis, C.R.; Burns, D.J.
Molecular and biochemical characterization of a recombinant human PKC-delta family member
Biochim. Biophys. Acta
1174
171-181
1993
Homo sapiens (Q05655), Homo sapiens
Johannes, F.J.; Prestle, J.; Eis, S.; Oberhagemann, P.; Pfizenmaier, K.
PKCu is a novel, atypical member of the protein kinase C family
J. Biol. Chem.
269
6140-6148
1994
Homo sapiens (Q15139), Homo sapiens
Palmer, R.H.; Ridden, J.; Parker, P.J.
Cloning and expression patterns of two members of a novel protein-kinase-C-related kinase family
Eur. J. Biochem.
227
344-351
1995
Homo sapiens (Q16512), Homo sapiens (Q16513)
Mukai, H.; Ono, Y.
A novel protein kinase with leucine zipper-like sequences: its catalytic domain is highly homologous to that of protein kinase C
Biochem. Biophys. Res. Commun.
199
897-904
1994
Homo sapiens (Q16512), Homo sapiens, Rattus norvegicus (Q63433)
Meyer, M.C.; Kell, P.J.; Creer, M.H.; McHowat, J.
Calcium-independent phospholipase A2 is regulated by a novel protein kinase C in human coronary artery endothelial cells
Am. J. Physiol.
288
C475-482
2005
Homo sapiens
Bain, J.; McLauchlan, H.; Elliott, M.; Cohen, P.
The specificities of protein kinase inhibitors: an update
Biochem. J.
371
199-204
2003
Homo sapiens
Violin, J.D.; Newton, A.C.
Pathway illuminated: visualizing protein kinase C signaling
IUBMB Life
55
653-660
2003
Homo sapiens, Mus musculus
Crosby, D.; Poole, A.W.
Physical and functional interaction between protein kinase C delta and Fyn tyrosine kinase in human platelets
J. Biol. Chem.
278
24533-24541
2003
Homo sapiens
Chen, J.S.; Exton, J.H.
Regulation of phospholipase D2 activity by protein kinase Calpha
J. Biol. Chem.
279
22076-22083
2004
Homo sapiens
Uchino, M.; Sakai, N.; Kashiwagi, K.; Shirai, Y.; Shinohara, Y.; Hirose, K.; Iino, M.; Yamamura, T.; Saito, N.
Isoform-specific phosphorylation of metabotropic glutamate receptor 5 by protein kinase C (PKC) blocks Ca2+ oscillation and oscillatory translocation of Ca2+-dependent PKC
J. Biol. Chem.
279
2254-2261
2004
Homo sapiens
Becker, K.P.; Hannun, Y.A.
Isoenzyme-specific translocation of protein kinase C (PKC)betaII and not PKCbetaI to a juxtanuclear subset of recycling endosomes: involvement of phospholipase D
J. Biol. Chem.
279
28251-28256
2004
Homo sapiens
Ranganathan, S.; Liu, C.X.; Migliorini, M.M.; Von Arnim, C.A.; Peltan, I.D.; Mikhailenko, I.; Hyman, B.T.; Strickland, D.K.
Serine and threonine phosphorylation of the low density lipoprotein receptor-related protein by protein kinase Calpha regulates endocytosis and association with adaptor molecules
J. Biol. Chem.
279
40536-40544
2004
Homo sapiens, Rattus norvegicus
Nozawa, Y.; Nishihara, K.; Akizawa, Y.; Orimoto, N.; Nakano, M.; Uji, T.; Ajioka, H.; Kanda, A.; Matsuura, N.; Kiniwa, M.
Protein kinase C activation by Helicobacter pylori in human gastric epithelial cells limits interleukin-8 production through suppression of extracellular signal-regulated kinase
J. Pharmacol. Sci.
94
233-239
2004
Homo sapiens
Spitaler, M.; Cantrell, D.A.
Protein kinase C and beyond
Nat. Immunol.
5
785-790
2004
Caenorhabditis elegans, Homo sapiens, Solanum lycopersicum, Mus musculus
Kamimura, K.; Hojo, H.; Abe, M.
Characterization of expression of protein kinase C isozymes in human B-cell lymphoma: Relationship between its expression and prognosis
Pathol. Int.
54
224-230
2004
Homo sapiens
Budas, G.R.; Koyanagi, T.; Churchill, E.N.; Mochly-Rosen, D.
Competitive inhibitors and allosteric activators of protein kinase C isoenzymes: a personal account and progress report on transferring academic discoveries to the clinic
Biochem. Soc. Trans.
35
1021-1026
2007
Homo sapiens, Xenopus laevis
Grodsky, N.; Li, Y.; Bouzida, D.; Love, R.; Jensen, J.; Nodes, B.; Nonomiya, J.; Grant, S.
Structure of the catalytic domain of human protein kinase C beta II complexed with a bisindolylmaleimide inhibitor
Biochemistry
45
13970-13981
2006
Homo sapiens
Abeyweera, T.P.; Rotenberg, S.A.
Design and characterization of a traceable protein kinase Calpha
Biochemistry
46
2364-2370
2007
Homo sapiens
Los, A.P.; de Widt, J.; Topham, M.K.; van Blitterswijk, W.J.; Divecha, N.
Protein kinase C inhibits binding of diacylglycerol kinase-zeta to the retinoblastoma protein
Biochim. Biophys. Acta
1773
352-357
2007
Homo sapiens
Abeywickrama, C.; Rotenberg, S.A.; Baker, A.D.
Inhibition of protein kinase C by dequalinium analogues: structure-activity studies on head group variations
Bioorg. Med. Chem.
14
7796-7803
2006
Homo sapiens
Li, J.; Qu, Y.; Zu, P.; Han, S.; Gao, G.; Xu, Q.; Fang, L.
Increased isoform-specific membrane translocation of conventional and novel protein kinase C in human neuroblastoma SH-SY5Y cells following prolonged hypoxia
Brain Res.
1093
25-32
2006
Homo sapiens
Chwae, Y.J.; Lee, J.M.; Kim, E.J.; Lee, S.T.; Soh, J.W.; Kim, J.
Activation-induced upregulation of inhibitory killer Ig-like receptors is regulated by protein kinase C
Immunol. Cell Biol.
85
220-228
2007
Homo sapiens
Alvarez-Arias, D.A.; Campbell, K.S.
Protein kinase C regulates expression and function of inhibitory killer cell Ig-like receptors in NK cells
J. Immunol.
179
5281-5290
2007
Homo sapiens
Bowley, K.A.; Linley, J.E.; Robins, G.G.; Kopanati, S.; Hunter, M.; Sandle, G.I.
Role of protein kinase C in aldosterone-induced non-genomic inhibition of basolateral potassium channels in human colonic crypts
J. Steroid Biochem. Mol. Biol.
104
45-52
2007
Homo sapiens
Sampson, S.R.; Cooper, D.R.
Specific protein kinase C isoforms as transducers and modulators of insulin signaling
Mol. Genet. Metab.
89
32-47
2006
Homo sapiens, Mus musculus, Rattus norvegicus
Cerda, S.R.; Mustafi, R.; Little, H.; Cohen, G.; Khare, S.; Moore, C.; Majumder, P.; Bissonnette, M.
Protein kinase C delta inhibits Caco-2 cell proliferation by selective changes in cell cycle and cell death regulators
Oncogene
25
3123-3138
2006
Homo sapiens
Kocanova, S.; Hornakova, T.; Hritz, J.; Jancura, D.; Chorvat, D.; Mateasik, A.; Ulicny, J.; Refregiers, M.; Maurizot, J.C.; Miskovsky, P.
Characterization of the interaction of hypericin with protein kinase C in U-87 MG human glioma cells
Photochem. Photobiol.
82
720-728
2006
Homo sapiens
Baskar, R.; Balajee, A.S.; Geard, C.R.; Hande, M.P.
Isoform-specific activation of protein kinase C in irradiated human fibroblasts and their bystander cells
Int. J. Biochem. Cell Biol.
40
125-134
2008
Homo sapiens, Homo sapiens (P05771), Homo sapiens (Q05513)
Caunt, C.J.; Rivers, C.A.; Conway-Campbell, B.L.; Norman, M.R.; McArdle, C.A.
Epidermal growth factor receptor and protein kinase C signaling to ERK2: Spatiotemporal regulation of ERK2 by dual specificity phosphatases
J. Biol. Chem.
283
6241-6252
2008
Homo sapiens
Oh, Y.; Herbst, R.S.; Burris, H.; Cleverly, A.; Musib, L.; Lahn, M.; Bepler, G.
Enzastaurin, an oral serine/threonine kinase inhibitor, as second- or third-line therapy of non-small-cell lung cancer
J. Clin. Oncol.
26
1135-1141
2008
Homo sapiens
Alfa Cisse, M.; Louis, K.; Braun, U.; Mari, B.; Leitges, M.; Slack, B.E.; Fisher, A.; Auberger, P.; Checler, F.; Vincent, B.
Isoform-specific contribution of protein kinase C to prion processing
Mol. Cell. Neurosci.
39
400-410
2008
Homo sapiens (P17252), Homo sapiens (Q02156), Homo sapiens (Q05513), Homo sapiens (Q05655)
Chahine, M.; Qu, Y.; Mancarella, S.; Boutjdir, M.
Protein kinase C activation inhibits alpha1D L-type Ca channel: a single-channel analysis
Pflugers Arch.
455
913-919
2008
Homo sapiens
Kang, J.H.; Asai, D.; Yamada, S.; Toita, R.; Oishi, J.; Mori, T.; Niidome, T.; Katayama, Y.
A short peptide is a protein kinase C (PKC) alpha-specific substrate
Proteomics
8
2006-2011
2008
Homo sapiens (P05129), Homo sapiens (P05771), Homo sapiens (P17252), Homo sapiens (P24723), Homo sapiens (P41743), Homo sapiens (Q02156), Homo sapiens (Q04759), Homo sapiens (Q05513), Homo sapiens (Q05655), Homo sapiens
Peng, H.; Lewandrowski, U.; Mueller, B.; Sickmann, A.; Walz, G.; Wegierski, T.
Identification of a protein kinase C-dependent phosphorylation site involved in sensitization of TRPV4 channel
Biochem. Biophys. Res. Commun.
391
1721-1725
2010
Homo sapiens
Conner, M.T.; Conner, A.C.; Brown, J.E.; Bill, R.M.
Membrane trafficking of aquaporin 1 is mediated by protein kinase C via microtubules and regulated by tonicity
Biochemistry
49
821-823
2010
Homo sapiens
Deyev, I.E.; Petrenko, A.G.
Regulation of CIRL-1 proteolysis and trafficking
Biochimie
92
418-422
2010
Homo sapiens
Freitas, M.; Porto, G.; Lima, J.L.; Fernandes, E.
Zinc activates neutrophils oxidative burst
Biometals
23
31-41
2010
Homo sapiens
Jokinen, J.; White, D.J.; Salmela, M.; Huhtala, M.; Kaepylae, J.; Sipilae, K.; Puranen, J.S.; Nissinen, L.; Kankaanpaeae, P.; Marjomaeki, V.; Hyypiae, T.; Johnson, M.S.; Heino, J.
Molecular mechanism of alpha2beta1 integrin interaction with human echovirus 1
EMBO J.
29
196-208
2010
Homo sapiens
Martin, P.; Pognonec, P.
ERK and cell death: cadmium toxicity, sustained ERK activation and cell death
FEBS J.
277
39-46
2010
Homo sapiens
Cai, J.; Crotty, T.M.; Reichert, E.; Carraway, K.L.; Stafforini, D.M.; Topham, M.K.
Diacylglycerol kinase (delta) and protein kinase Calpha modulate epidermal growth factor receptor abundance and degradation through ubiquitin-specific protease 8
J. Biol. Chem.
285
6952-6959
2010
Homo sapiens
Oyesanya, R.A.; Greenbaum, S.; Dang, D.; Lee, Z.; Mukherjee, A.; Wu, J.; Dent, P.; Fang, X.
Differential requirement of the epidermal growth factor receptor for G protein-mediated activation of transcription factors by lysophosphatidic acid
Mol. Cancer
9
8-8
2010
Homo sapiens
Bruns, A.F.; Herbert, S.P.; Odell, A.F.; Jopling, H.M.; Hooper, N.M.; Zachary, I.C.; Walker, J.H.; Ponnambalam, S.
Ligand-stimulated VEGFR2 signaling is regulated by co-ordinated trafficking and proteolysis
Traffic
11
161-174
2010
Homo sapiens
Toita, R.; Mori, T.; Naritomi, Y.; Kang, J.H.; Shiosaki, S.; Niidome, T.; Katayama, Y.
Fluorometric detection of protein kinase Calpha activity based on phosphorylation-induced dissociation of a polyion complex
Anal. Biochem.
424
130-136
2012
Homo sapiens
Raveh-Amit, H.; Hai, N.; Rotem-Dai, N.; Shahaf, G.; Gopas, J.; Livneh, E.
Protein kinase Ceta activates NF-kappaB in response to camptothecin-induced DNA damage
Biochem. Biophys. Res. Commun.
412
313-317
2011
Homo sapiens
Dumont, O.; Mylroie, H.; Bauer, A.; Calay, D.; Sperone, A.; Thornton, C.; Hamdulay, S.S.; Ali, N.; Boyle, J.J.; Choo, J.R.; Samarel, A.M.; Haskard, D.O.; Randi, A.M.; Evans, P.C.; Mason, J.C.
Protein kinase Cepsilon activity induces anti-inflammatory and anti-apoptotic genes via an ERK1/2- and NF-kappaB-dependent pathway to enhance vascular protection
Biochem. J.
447
193-204
2012
Homo sapiens
Vijayakumar, B.; Velmurugan, D.
Designing of Protein Kinase C beta-II Inhibitors against Diabetic complications: Structure Based Drug Design, Induced Fit docking and analysis of active site conformational changes
Bioinformation
8
568-573
2012
Homo sapiens
Pavarotti, M.; Capmany, A.; Vitale, N.; Colombo, M.I.; Damiani, M.T.
Rab11 is phosphorylated by classical and novel protein kinase C isoenzymes upon sustained phorbol ester activation
Biol. Cell
104
102-115
2012
Homo sapiens
Li, H.; Hong, Y.; Nukui, S.; Lou, J.; Johnson, S.; Scales, S.; Botrous, I.; Tompkins, E.; Yin, C.; Zhou, R.; He, M.; Jensen, J.; Bouzida, D.; Alton, G.; Lafontaine, J.; Grant, S.
Identification of novel pyrrolopyrazoles as protein kinase C beta II inhibitors
Bioorg. Med. Chem. Lett.
21
584-587
2011
Homo sapiens
van Eis, M.J.; Evenou, J.P.; Floersheim, P.; Gaul, C.; Cowan-Jacob, S.W.; Monovich, L.; Rummel, G.; Schuler, W.; Stark, W.; Strauss, A.; von Matt, A.; Vangrevelinghe, E.; Wagner, J.; Soldermann, N.
2,6-Naphthyridines as potent and selective inhibitors of the novel protein kinase C isozymes
Bioorg. Med. Chem. Lett.
21
7367-7372
2011
Homo sapiens
Titchenell, P.M.; Hollis Showalter, H.D.; Pons, J.F.; Barber, A.J.; Jin, Y.; Antonetti, D.A.
Synthesis and structure-activity relationships of 2-amino-3-carboxy-4-phenylthiophenes as novel atypical protein kinase C inhibitors
Bioorg. Med. Chem. Lett.
23
3034-3038
2013
Homo sapiens
Liu, Y.; Song, R.; Gao, Y.; Li, Y.; Wang, S.; Liu, H.Y.; Wang, Y.; Hu, Y.H.; Shu, H.B.
Protein kinase C-delta negatively regulates T cell receptor-induced NF-?B activation by inhibiting the assembly of CARMA1 signalosome
J. Biol. Chem.
287
20081-20087
2012
Homo sapiens
Lee, A.
The role of atypical protein kinase C in CSF-1-dependent Erk activation and proliferation in myeloid progenitors and macrophages
PLoS ONE
6
e25580
2011
Homo sapiens
Lopez-Sanchez, I.; Garcia-Marcos, M.; Mittal, Y.; Aznar, N.; Farquhar, M.G.; Ghosh, P.
Protein kinase C-theta (PKCtheta) phosphorylates and inhibits the guanine exchange factor, GIV/Girdin
Proc. Natl. Acad. Sci. USA
110
5510-5515
2013
Homo sapiens
Van Wandelen, L.; Van Ameijde, J.; Ismail-Ali, A.; Van Ufford, H.; Vijftigschild, L.; Beekman, J.; Martin, N.; Ruijtenbeek, R.; Liskamp, R.
Cell-penetrating bisubstrate-based protein kinase C inhibitors
ACS Chem. Biol.
8
1479-1487
2013
Homo sapiens
Meng, Z.; Bischof, J.; Ianes, C.; Henne-Bruns, D.; Xu, P.; Knippschild, U.
CK1delta kinase activity is modulated by protein kinase C alpha (PKCalpha)-mediated site-specific phosphorylation
Amino Acids
48
1185-1197
2016
Homo sapiens
Lee, Y.H.; Park, J.W.; Bae, Y.S.
Regulation of protein kinase CK2 catalytic activity by protein kinase C and phospholipase D2
Biochimie
121
131-139
2016
Homo sapiens
Pavlovic, Z.; Zhu, L.; Pereira, L.; Singh, R.; Cornel, R.; Bakovic, M.
Isoform-specific and protein kinase C-mediated regulation of CTP:phosphoethanolamine cytidylyltransferase phosphorylation
J. Biol. Chem.
289
9053-9064
2014
Homo sapiens
Sommese, R.; Sivaramakrishnan, S.
Substrate affinity differentially influences protein kinase C regulation and inhibitor potency
J. Biol. Chem.
291
21963-21970
2016
Homo sapiens
Ninsontia, C.; Phiboonchaiyanan, P.P.; Kiratipaiboon, C.; Chanvorachote, P.
Zinc suppresses stem cell properties of lung cancer cells through protein kinase C-mediated beta-catenin degradation
Am. J. Physiol. Cell Physiol.
312
C487-C499
2017
Homo sapiens (P17252)
Meng, Z.; B hm, T.; Xu, P.; Henne-Bruns, D.; Peifer, C.; Witt, L.; Knippschild, U.; Bischof, J.
Kinase activity of casein kinase 1 delta (CK1delta)is modulated by protein kinase C alpha (PKCalpha) by site-specific phosphorylation within the kinase domain of CK1delta
Biochim. Biophys. Acta
1867
710-721
2019
Homo sapiens (P17252)
Meng, Z.; Bhm, T.; Xu, P.; Henne-Bruns, D.; Peifer, C.; Witt, L.; Knippschild, U.; Bischof, J.
Kinase activity of casein kinase 1 delta (CK1delta) is modulated by protein kinase Calpha (PKCalpha) by site-specific phosphorylation within the kinase domain of CK1delta
Biochim. Biophys. Acta Proteins Proteom.
1867
710-721
2019
Homo sapiens (P17252)
Katoh, T.; Tomata, Y.; Setoh, M.; Sasaki, S.; Takai, T.; Yoshitomi, Y.; Yukawa, T.; Nakagawa, H.; Fukumoto, S.; Tsukamoto, T.; Nakada, Y.
Practical application of 3-substituted-2,6-difluoropyridines in drug discovery Facile synthesis of novel protein kinase C theta inhibitors
Bioorg. Med. Chem. Lett.
27
2497-2501
2017
Homo sapiens (Q04759)
Holmgren, C.; Cornmark, L.; Lonne, G.K.; Masoumi, K.C.; Larsson, C.
Molecular characterization of protein kinase C delta (PKCdelta)-Smac interactions
BMC Biochem.
17
11
2016
Homo sapiens (Q05655)
