Activating Compound | Comment | Organism | Structure |
---|---|---|---|
phorbol 12-myristate 13-acetate | i.e. PMA | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
isozymes PKCbetaII and PKCbetaI are products of alternative splicing of gene PKCbeta, expression of GFP- or HA-tagged isozymes PKCbetaII, wild-type and mutant, and PKCbetaI in HEK-293 or HeLa cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
K371R | site-directed mutagenesis, inactive isozyme PKCbetaII mutant | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | non-activated PKCbetaII and PKCbetaI | Homo sapiens | 5737 | - |
endosome | activated PKCbetaII and PKCbetaI are translocated from cytosol, juxtanuclear location, isozyme-specific translocation of PKCbetaII and not PKCbetaI to a juxtanuclear subset of recycling endosomes, involvement of phospholipase D | Homo sapiens | 5768 | - |
additional information | subcellular distribution of isozymes PKCbetaII and PKCbetaI | Homo sapiens | - |
- |
plasma membrane | activated PKCbetaII and PKCbetaI are translocated from cytosol | Homo sapiens | 5886 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
isozymes PKCbetaII and PKCbetaI | - |
Synonyms | Comment | Organism |
---|---|---|
PKC | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |