6.1.1.3: threonine-tRNA ligase

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For detailed information about threonine-tRNA ligase, go to the full flat file.

Reaction

Synonyms

ApThrRS-1, ApThrRS-2, BaThrRS, EcThrRS, ectRNAThr, McThrRS, mitochondrial threonyl-tRNA synthetase, MJ1197, MmThrRS, More, Mst1, ScmtThrRS, SfThrRS-1, SfThrRS-2, Synthetase, threonyl-transfer ribonucleate, TarS, Thr-tRNA synthetase, Threonine translase, Threonine--tRNA ligase, Threonine-transfer ribonucleate synthetase, threonyl tRNA synthetase, Threonyl-ribonucleic synthetase, Threonyl-transfer ribonucleate synthetase, Threonyl-transfer ribonucleic acid synthetase, Threonyl-transfer RNA synthetase, Threonyl-tRNA synthetase, ThrRS, ThrRS1, ThrS, TRS

ECTree

     6 Ligases

         6.1 Forming carbon-oxygen bonds

             6.1.1 Ligases forming aminoacyl-tRNA and related compounds

                6.1.1.3 threonine-tRNA ligase

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Results	in table
3	Activating Compound
55679	AA Sequence
2	Application
1	CAS Registry Number
35	Cloned(Commentary)
64	Cofactor
20	Crystallization (Commentary)
73	Disease/ Diagnostics
1	Expression
41	General Information
128	Inhibitors
11	kcat/KM [mM/s]
106	Ki Value [mM]
98	KM Value [mM]
24	Localization
61	Metals/Ions
20	Molecular Weight [Da]
78	Natural Substrates/ Products (Substrates)
246	Organism
4	Pathway
136	PDB ID
29	pH Optimum
1	Posttranslational Modification
102	Protein Variants
34	Purification (Commentary)
12	Reaction
27	Reaction Type
104	Reference
1	Renatured (Commentary)
23	Source Tissue
6	Specific Activity [micromol/min/mg]
4	Storage Stability
176	Substrates and Products (Substrate)
25	Subunits
259	Synonyms
1	Systematic Name
28	Temperature Optimum [°C]
2	Temperature Stability [°C]
75	Turnover Number [1/s]

Expression

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Expression on EC 6.1.1.3 - threonine-tRNA ligase

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

TARS expression is increased in epithelial ovarian cancer and correlates with markers of angiogenic progression. TARS is overexpressed in infiltrating leukocytes within ovarian tumors

Homo sapiens

P26639

744595