Information on EC 6.1.1.3 - Threonine-tRNA ligase

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The expected taxonomic range for this enzyme is: Archaea, Eukaryota, Bacteria

EC NUMBER
COMMENTARY
6.1.1.3
-
RECOMMENDED NAME
GeneOntology No.
Threonine-tRNA ligase
PATHWAY
KEGG Link
MetaCyc Link
Aminoacyl-tRNA biosynthesis
-
tRNA charging
-
SYSTEMATIC NAME
IUBMB Comments
L-Threonine:tRNAThr ligase (AMP-forming)
-
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
ApThrRS-1
-
protein contains the catalytic domain of ThrRS
ApThrRS-1
Q9YDW0
-
ApThrRS-2
-
protein contains the editing domain of ThrRS
ApThrRS-2
Q9YFY3
-
SfThrRS-1
-
protein contains the catalytic domain of ThrRS
SfThrRS-2
-
protein contains the editing domain of ThrRS
Synthetase, threonyl-transfer ribonucleate
-
-
-
-
Synthetase, threonyl-transfer ribonucleate
Q9YFY3
-
Synthetase, threonyl-transfer ribonucleate
-
-
Synthetase, threonyl-transfer ribonucleate
-
-
Synthetase, threonyl-transfer ribonucleate
-
-
Synthetase, threonyl-transfer ribonucleate
-
-
Synthetase, threonyl-transfer ribonucleate
-
-
Thr-tRNA synthetase
-
-
Thr-tRNA synthetase
-
-
Threonine translase
-
-
-
-
Threonine translase
Q9YFY3
-
Threonine translase
-
-
Threonine translase
-
-
Threonine translase
-
-
Threonine translase
-
-
Threonine--tRNA ligase
-
-
-
-
Threonine--tRNA ligase
Q9YFY3
-
Threonine--tRNA ligase
-
-
Threonine--tRNA ligase
-
-
Threonine--tRNA ligase
-
-
Threonine--tRNA ligase
-
-
Threonine-transfer ribonucleate synthetase
-
-
-
-
Threonine-transfer ribonucleate synthetase
Q9YFY3
-
Threonine-transfer ribonucleate synthetase
-
-
Threonine-transfer ribonucleate synthetase
-
-
Threonine-transfer ribonucleate synthetase
-
-
Threonine-transfer ribonucleate synthetase
-
-
Threonine-transfer ribonucleate synthetase
-
-
Threonyl-ribonucleic synthetase
-
-
-
-
Threonyl-ribonucleic synthetase
Q9YFY3
-
Threonyl-ribonucleic synthetase
-
-
Threonyl-ribonucleic synthetase
-
-
Threonyl-ribonucleic synthetase
-
-
Threonyl-ribonucleic synthetase
-
-
Threonyl-ribonucleic synthetase
-
-
Threonyl-transfer ribonucleate synthetase
-
-
-
-
Threonyl-transfer ribonucleate synthetase
Q9YFY3
-
Threonyl-transfer ribonucleate synthetase
-
-
Threonyl-transfer ribonucleate synthetase
-
-
Threonyl-transfer ribonucleate synthetase
-
-
Threonyl-transfer ribonucleate synthetase
-
-
Threonyl-transfer ribonucleate synthetase
-
-
Threonyl-transfer ribonucleic acid synthetase
-
-
-
-
Threonyl-transfer ribonucleic acid synthetase
Q9YFY3
-
Threonyl-transfer ribonucleic acid synthetase
-
-
Threonyl-transfer ribonucleic acid synthetase
-
-
Threonyl-transfer ribonucleic acid synthetase
-
-
Threonyl-transfer ribonucleic acid synthetase
-
-
Threonyl-transfer ribonucleic acid synthetase
-
-
Threonyl-transfer RNA synthetase
-
-
-
-
Threonyl-transfer RNA synthetase
Q9YFY3
-
Threonyl-transfer RNA synthetase
-
-
Threonyl-transfer RNA synthetase
-
-
Threonyl-transfer RNA synthetase
-
-
Threonyl-transfer RNA synthetase
-
-
Threonyl-transfer RNA synthetase
-
-
Threonyl-tRNA synthetase
-
-
-
-
Threonyl-tRNA synthetase
-
-
Threonyl-tRNA synthetase
Q9YDW0
-
Threonyl-tRNA synthetase
Q9YFY3
-
Threonyl-tRNA synthetase
-
-
Threonyl-tRNA synthetase
-
-
Threonyl-tRNA synthetase
-
-
Threonyl-tRNA synthetase
Escherichia coli MG1655
-
-
-
Threonyl-tRNA synthetase
-
-
Threonyl-tRNA synthetase
-
-
Threonyl-tRNA synthetase
-
-
Threonyl-tRNA synthetase
-
-
Threonyl-tRNA synthetase
-
-
Threonyl-tRNA synthetase
-
-
Threonyl-tRNA synthetase
-
-
ThrRS
-
-
-
-
ThrRS
Q9YDW0
-
ThrRS
Escherichia coli MG1655
-
-
-
TRS
-
-
-
-
TRS
Q9YFY3
-
mitochondrial threonyl-tRNA synthetase
-
-
additional information
-
the enzyme belongs to the class II aminoacyl-tRNA synthetases
CAS REGISTRY NUMBER
COMMENTARY
9023-46-5
-
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
isozyme ThrRS-1, K1, extreme thermophilic archaeon
GenBank
Manually annotated by BRENDA team
isozyme ThrRS-2, K1, extreme thermophilic archaeon
GenBank
Manually annotated by BRENDA team
several creanarchaea including Aeropyrum pernix K1 and Sulfolobus tokodaii strain 7 contain two genes encoding either the catalytic or the editing domain of ThrRS
-
-
Manually annotated by BRENDA team
parental GAT-cell line and borrelidin-resistant derivative 2000A
-
-
Manually annotated by BRENDA team
class II enzyme
-
-
Manually annotated by BRENDA team
class II enzyme, recombinantly overexpressed and purified enzyme
-
-
Manually annotated by BRENDA team
K12, wild-type and borrelidin-resistant mutant
-
-
Manually annotated by BRENDA team
overproducing strain
-
-
Manually annotated by BRENDA team
several strains, overview, gene thrS
-
-
Manually annotated by BRENDA team
Escherichia coli MG1655
-
-
-
Manually annotated by BRENDA team
Escherichia coli overproducing
overproducing strain
-
-
Manually annotated by BRENDA team
extreme halophilic archaeon
-
-
Manually annotated by BRENDA team
Saccharomyces cerevisiae D273-10B
D273-10B
-
-
Manually annotated by BRENDA team
several creanarchaea including Aeropyrum pernix K1 and Sulfolobus tokodaii strain 7 contain two genes encoding either the catalytic or the editing domain of ThrRS
-
-
Manually annotated by BRENDA team
overproduced in Escherichia coli
-
-
Manually annotated by BRENDA team
strain HB8
-
-
Manually annotated by BRENDA team
PDB
SCOP
CATH
ORGANISM
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Pyrococcus abyssi (strain GE5 / Orsay)
Pyrococcus abyssi (strain GE5 / Orsay)
Pyrococcus abyssi (strain GE5 / Orsay)
Pyrococcus abyssi (strain GE5 / Orsay)
Pyrococcus abyssi (strain GE5 / Orsay)
Pyrococcus abyssi (strain GE5 / Orsay)
Pyrococcus abyssi (strain GE5 / Orsay)
Pyrococcus abyssi (strain GE5 / Orsay)
Pyrococcus abyssi (strain GE5 / Orsay)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Staphylococcus aureus (strain MW2)
Staphylococcus aureus (strain MW2)
TEMPERATURE STABILITY
TEMPERATURE STABILITY MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
60
-
-
12 min, incubation without substrates, 50% inactivation
additional information
-
-
threonine does not influence the rate of heat inactivation. ATP and tRNA labilize