5.4.99.25: tRNA pseudouridine55 synthase

This is an abbreviated version!
For detailed information about tRNA pseudouridine55 synthase, go to the full flat file.

Reaction

Synonyms

aCBF5, Cbf5, Mj-Pus10, MjPus10, More, pfuCbf5, pseudouridine 55 synthase, pseudouridine synthase, pseudouridine synthase Pus10, pseudouridine synthase TruB, pseuduridine-55 synthase, PSI synthase, PSI synthase TruB, PSI55 synthase, PSI55 synthaseuB, psi55 tRNA pseudouridine synthase, psi55S, Pus10, Pus4, RNA pseudouridine synthase TruB, TR, tRNA pseudouridine 55 synthase, tRNA pseudouridine synthase, tRNA PSI 55 synthase, tRNA:pseudouridine-55 synthase, tRNA:PSI55 synthase, tRNA:PSI55-synthase, TruB, YNL292w

ECTree

     5 Isomerases

         5.4 Intramolecular transferases

             5.4.99 Transferring other groups

                5.4.99.25 tRNA pseudouridine55 synthase

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Results	in table
6	Activating Compound
49363	AA Sequence
2	CAS Registry Number
13	Cloned(Commentary)
7	Crystallization (Commentary)
15	Disease/ Diagnostics
12	General Information
1	Inhibitors
10	kcat/KM [mM/s]
14	KM Value [mM]
2	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
31	Organism
5	pH Optimum
35	Protein Variants
9	Purification (Commentary)
7	Reaction
30	Reference
1	Source Tissue
23	Substrates and Products (Substrate)
3	Subunits
50	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Temperature Stability [°C]
14	Turnover Number [1/s]

Disease

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Disease on EC 5.4.99.25 - tRNA pseudouridine55 synthase

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Autoimmune Diseases

Expression patterns common and unique to ulcerative colitis and celiac disease.

30402962

Celiac Disease

A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease.

21298027

Crohn Disease

A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease.

21298027

Neoplasms

Reciprocal amplification of caspase-3 activity by nuclear export of a putative human RNA-modifying protein, PUS10 during TRAIL-induced apoptosis.

28981101

Tuberculosis

Crystal structure of the apo forms of psi 55 tRNA pseudouridine synthase from Mycobacterium tuberculosis: a hinge at the base of the catalytic cleft.

15028724

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