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5.4.99.25: tRNA pseudouridine55 synthase

This is an abbreviated version!
For detailed information about tRNA pseudouridine55 synthase, go to the full flat file.

Word Map on EC 5.4.99.25

Reaction

tRNA uridine55
=
tRNA pseudouridine55

Synonyms

aCBF5, Cbf5, Mj-Pus10, MjPus10, More, pfuCbf5, pseudouridine 55 synthase, pseudouridine synthase, pseudouridine synthase Pus10, pseudouridine synthase TruB, pseuduridine-55 synthase, PSI synthase, PSI synthase TruB, PSI55 synthase, PSI55 synthaseuB, psi55 tRNA pseudouridine synthase, psi55S, Pus10, Pus4, RNA pseudouridine synthase TruB, TR, tRNA pseudouridine 55 synthase, tRNA pseudouridine synthase, tRNA PSI 55 synthase, tRNA:pseudouridine-55 synthase, tRNA:PSI55 synthase, tRNA:PSI55-synthase, TruB, YNL292w

ECTree

     5 Isomerases
         5.4 Intramolecular transferases
             5.4.99 Transferring other groups
                5.4.99.25 tRNA pseudouridine55 synthase

Reference

Reference on EC 5.4.99.25 - tRNA pseudouridine55 synthase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Becker, H.F.; Motorin, Y.; Planta, R.J.; Grosjean, H.
The yeast gene YNL292w encodes a pseudouridine synthase (Pus4) catalyzing the formation of psi 55 in both mitochondrial and cytoplasmatic tRNAs
Nucleic Acids Res.
25
4493-4499
1997
Saccharomyces cerevisiae (P48567), Saccharomyces cerevisiae
Manually annotated by BRENDA team
Ramamurthy, V.; Swann, S.; Spedaliere, C.; Mueller, E.
Role of cysteine residues in pseudouridine synhases of different families
Biochemistry
38
13106-13111
1999
Escherichia coli (P60340)
Manually annotated by BRENDA team
Hoang, C.; Ferre-D'Amare, A.R.
Cocrystal structure of a tRNA psi55 pseudouridine synthase: nucleotide flipping by an RNA-modifying enzyme
Cell
107
929-939
2001
Escherichia coli (P60340)
Manually annotated by BRENDA team
Chaudhuri, B.N.; Chan, S.; Perry, L.J.; Yeates, T.O.
Crystal structure of the apo forms of psi55 tRNA pseudouridine synthase from Mycobacterium tuberculosis. A hinge at the base of the catalytic cleft
J. Biol. Chem.
279
24585-24591
2004
Mycobacterium tuberculosis (P9WHP7), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WHP7)
Manually annotated by BRENDA team
Pan, H.; Agarwalla, S.; Moustakas, D.T.; Finer-Moore, J.; Stroud, R.M.
Structure of tRNA pseudouridine synthase TruB and its RNA complex: RNA recognition through a combination of rigid docking and induced fit
Proc. Natl. Acad. Sci. USA
100
12648-12653
2003
Escherichia coli (P60340), Thermotoga maritima (Q9WZW0)
Manually annotated by BRENDA team
Phannachet, K.; Elias, Y.; Huang, R.H.
Dissecting the roles of a strictly conserved tyrosine in substrate recognition and catalysis by pseudouridine 55 synthase
Biochemistry
44
15488-15494
2005
Thermotoga maritima (Q9WZW0), Thermotoga maritima
Manually annotated by BRENDA team
Hoang, C.; Hamilton, C.S.; Mueller, E.G.; Ferre-D'Amare, A.R.
Precursor complex structure of pseudouridine synthase TruB suggests coupling of active site perturbations to an RNA-sequestering peripheral protein domain
Protein Sci.
14
2201-2206
2005
Escherichia coli (P60340)
Manually annotated by BRENDA team
Gurha, P.; Gupta, R.
Archaeal Pus10 proteins can produce both pseudouridine 54 and 55 in tRNA
RNA
14
2521-2527
2008
Methanocaldococcus jannaschii, Pyrococcus furiosus
Manually annotated by BRENDA team
Pienkowska, J.; Wrzesinski, J.; Szweykowska-Kulinska, Z.
A cell-free yellow lupin extract containing activities of pseudouridine 35 and 55 synthases
Acta Biochim. Pol.
45
745-754
1998
Lupinus luteus
Manually annotated by BRENDA team
Gu, X.; Yu, M.; Ivanetich, K.M.; Santi, D.V.
Molecular recognition of tRNA by tRNA pseudouridine 55 synthase
Biochemistry
37
339-343
1998
Escherichia coli
Manually annotated by BRENDA team
Spedaliere, C.J.; Hamilton, C.S.; Mueller, E.G.
Functional importance of motif I of pseudouridine synthases: mutagenesis of aligned lysine and proline residues
Biochemistry
39
9459-9465
2000
Escherichia coli (P60340)
Manually annotated by BRENDA team
Urbonavicius, J.; Durand, J.M.; Björk, G.R.
Three modifications in the D and T arms of tRNA influence translation in Escherichia coli and expression of virulence genes in Shigella flexneri
J. Bacteriol.
184
5348-5357
2002
Escherichia coli, Shigella flexneri
Manually annotated by BRENDA team
Kinghorn, S.M.; O'Byrne, C.P.; Booth, I.R.; Stansfield, I.
Physiological analysis of the role of truB in Escherichia coli: a role for tRNA modification in extreme temperature resistance
Microbiology
148
3511-3520
2002
Escherichia coli (P60340)
Manually annotated by BRENDA team
Roovers, M.; Hale, C.; Tricot, C.; Terns, M.P.; Terns, R.M.; Grosjean, H.; Droogmans, L.
Formation of the conserved pseudouridine at position 55 in archaeal tRNA
Nucleic Acids Res.
34
4293-4301
2006
Pyrococcus furiosus
Manually annotated by BRENDA team
Muller, S.; Fourmann, J.B.; Loegler, C.; Charpentier, B.; Branlant, C.
Identification of determinants in the protein partners aCBF5 and aNOP10 necessary for the tRNA:Psi55-synthase and RNA-guided RNA:PSI-synthase activities
Nucleic Acids Res.
35
5610-5624
2007
Pyrococcus abyssi (Q9V1A5)
Manually annotated by BRENDA team
Gurha, P.; Joardar, A.; Chaurasia, P.; Gupta, R.
Differential roles of archaeal box H/ACA proteins in guide RNA-dependent and independent pseudouridine formation
RNA Biol.
4
101-109
2007
Methanocaldococcus jannaschii
Manually annotated by BRENDA team
Spedaliere, C.J.; Mueller, E.G.
Not all pseudouridine synthases are potently inhibited by RNA containing 5-fluorouridine
RNA
10
192-199
2004
Escherichia coli (P60340), Escherichia coli
Manually annotated by BRENDA team
Nurse, K.; Wrzesinski, J.; Bakin, A.; Lane, B.G.; Ofengand, J.
Purification, cloning, and properties of the tRNA PSI 55 synthase from Escherichia coli
RNA
1
102-112
1995
Escherichia coli (P60340), Escherichia coli
Manually annotated by BRENDA team
Gutgsell, N.; Englund, N.; Niu, L.; Kaya, Y.; Lane, B.G.; Ofengand, J.
Deletion of the Escherichia coli pseudouridine synthase gene truB blocks formation of pseudouridine 55 in tRNA in vivo, does not affect exponential growth, but confers a strong selective disadvantage in competition with wild-type cells
RNA
6
1870-1881
2000
Escherichia coli (P60340)
Manually annotated by BRENDA team
Fourmann, J.B.; Tillault, A.S.; Blaud, M.; Leclerc, F.; Branlant, C.; Charpentier, B.
Comparative study of two box H/ACA ribonucleoprotein pseudouridine-synthases: relation between conformational dynamics of the guide RNA, enzyme assembly and activity
PLoS One
8
e70313
2013
Pyrococcus abyssi
Manually annotated by BRENDA team
Joardar, A.; Jana, S.; Fitzek, E.; Gurha, P.; Majumder, M.; Chatterjee K, Geisler M, Gupta R.
Role of forefinger and thumb loops in production of Psi54 and Psi55 in tRNAs by archaeal Pus10
RNA
19
1279-1294
2013
Methanocaldococcus jannaschii (Q60346), Methanocaldococcus jannaschii DSM 2661 (Q60346)
Manually annotated by BRENDA team
Yang, W.; Zhao, S.; Jin, L.; Guo, Z.; Zhang, S.; Zhang, H.; Wang, D.
Purification, crystallization and preliminary X-ray crystallographic study of the tRNA pseudouridine synthase TruB from Streptococcus pneumoniae
Acta Crystallogr. Sect. F
69
759-761
2013
Streptococcus pneumoniae (Q97QJ3), Streptococcus pneumoniae
Manually annotated by BRENDA team
Friedt, J.; Leavens, F.M.; Mercier, E.; Wieden, H.J.; Kothe, U.
An arginine-aspartate network in the active site of bacterial TruB is critical for catalyzing pseudouridine formation
Nucleic Acids Res.
42
3857-3870
2014
Escherichia coli
Manually annotated by BRENDA team
Fitzek, E.; Joardar, A.; Gupta, R.; Geisler, M.
Evolution of eukaryal and archaeal pseudouridine synthase Pus10
J. Mol. Evol.
86
77-89
2018
Homo sapiens (Q3MIT2), Methanocaldococcus jannaschii (Q60346)
Manually annotated by BRENDA team