4.2.3.17: taxadiene synthase

This is an abbreviated version!
For detailed information about taxadiene synthase, go to the full flat file.

geranylgeranyl pyrophosphate cyclase, taxa-4(5),11(12)-diene synthase, taxadiene synthase, taxadiene synthase 5, TXS

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Results	in table
4	Activating Compound
6	AA Sequence
13	Application
1	CAS Registry Number
16	Cloned(Commentary)
1	Crystallization (Commentary)
2	General Information
2	kcat/KM [mM/s]
9	KM Value [mM]
4	Metals/Ions
2	Molecular Weight [Da]
27	Natural Substrates/ Products (Substrates)
36	Organism
7	Pathway
3	PDB ID
2	pH Optimum
5	Protein Variants
7	Purification (Commentary)
1	Reaction
10	Reaction Type
35	Reference
4	Source Tissue
3	Specific Activity [micromol/min/mg]
52	Substrates and Products (Substrate)
2	Subunits
25	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
7	Turnover Number [1/s]

Natural Substrates Products on EC 4.2.3.17 - taxadiene synthase

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(E,E,E)-geranylgeranyl diphosphate

taxa-4(5),11(12)-diene + diphosphate

first committed step of taxol biosynthesis

geranylgeranyl diphosphate

taxa-4(5),11(12)-diene + diphosphate

taxadiene biosynthetic pathway

precursor of the chemotherapeutic agent taxol

geranylgeranyl diphosphate

taxa-4,11-diene + diphosphate