Literature summary for 4.2.3.17 extracted from

Kovacs, K.; Zhang, L.; Linforth, R.S.; Whittaker, B.; Hayes, C.J.; Fray, R.G.
Redirection of carotenoid metabolism for the efficient production of taxadiene [taxa-4(5),11(12)-diene] in transgenic tomato fruit (2007), Transgenic Res., 16, 121-126.

Search for more literature for 4.2.3.17

Application

Application	Comment	Organism
medicine	taxanes can be used in cancer treatment	Taxus baccata

Cloned(Commentary)

Cloned (Comment)	Organism
cDNA is directly cloned into the pGemT-Easy vector, sequenced and cloned into the plant binary transformation vector pBC35. Furthermore it is subcloned into pBluescript, released and ligated into pRD12. The pBC35 and pRD12 constructs are transferred to Agrobacterium tumefaciens and used to transform tomato cotyledons	Taxus baccata

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
geranylgeranyl diphosphate	Taxus baccata	-	taxa-4,11-diene + diphosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Taxus baccata	Q93YA3	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
geranylgeranyl diphosphate	-	Taxus baccata	taxa-4,11-diene + diphosphate	-	?

Synonyms

Synonyms	Comment	Organism
taxadiene synthase	-	Taxus baccata

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Release 2023.1 (January 2023)