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4.1.1.48: indole-3-glycerol-phosphate synthase

This is an abbreviated version!
For detailed information about indole-3-glycerol-phosphate synthase, go to the full flat file.

Word Map on EC 4.1.1.48

Reaction

1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate
=
1-C-(indol-3-yl)glycerol 3-phosphate
+
CO2
+
H2O

Synonyms

eIGPS, IGP synthase, IGPS, indole-3-glycerol phosphate synthase, Indole-3-glycerol phosphate synthetase, Indole-3-glycerol-phosphate synthase, indole-3-glycerolphosphate synthase, Indole-3-glycerophosphate synthase, Indoleglycerol phosphate synthase, Indoleglycerol phosphate synthetase, Indoleglycerolphosphate synthetase, InGP synthase, InGP synthetase, InGPS, mIGPS, MtIGPS, Phosphoribosylanthranilate isomerase-indoleglycerol phosphate synthetase, Pk-trpC, PRAI, PRAI-InGPS, sIGPS, SSO0895, Synthase, indole-3-glycerol phosphate, TrpC

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.48 indole-3-glycerol-phosphate synthase

Molecular Weight

Molecular Weight on EC 4.1.1.48 - indole-3-glycerol-phosphate synthase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
155000
-
2 * 155000, SDS-PAGE
21000
-
gel filtration
22000
-
gel filtration
23500
23600
-
gel filtration
24200
gel filtration, N-terminal deletion mutant lacking 25 amino acids
26300
gel filtration, wild-type
26400
1 * 26400, N-terminal deletion mutant lacking 26 amino acids, 1 * 28600, wild-type, calculated
26600
27000
-
1 * 27000, SDS-PAGE
28000
-
SDS-PAGE, recombinant enzyme
28200
gel filtration, wild-type
28566
-
1 * 28566, calculation from nucleotide sequence
28600
28700
30000
-
gel-filtration chromatography
31000
32000
-
gel filtration
320000 - 340000
-
anthranilate synthetase complex, gel filtration
325000
-
bifunctional enzyme phosphoribosylanthranilate isomerase-indoleglycerol phosphate synthetase, gel filtration
39300
gel filtration, N-terminal deletion mutant lacking 25 amino acids
44000
-
equilibrium sedimentation
45000
47000
47100
gel filtration, wild-type
48000
53000
70000
-
2 * 94000 + 2 * 70000, anthranilate synthetase complex, one subunit is a trifunctional peptide which contains the catalytic sites for the phosphoribosylanthranilate isomerase and indoleglycerol phosphate synthetase reactions, and associates with the second subunit to form glutamine-dependent anthranilate synthetase, SDS-PAGE
94000
-
2 * 94000 + 2 * 70000, anthranilate synthetase complex, one subunit is a trifunctional peptide which contains the catalytic sites for the phosphoribosylanthranilate isomerase and indoleglycerol phosphate synthetase reactions, and associates with the second subunit to form glutamine-dependent anthranilate synthetase, SDS-PAGE