3.6.1.29: bis(5'-adenosyl)-triphosphatase

This is an abbreviated version!
For detailed information about bis(5'-adenosyl)-triphosphatase, go to the full flat file.

Word Map on EC 3.6.1.29

3.6.1.29

carcinogenesis

heterozygosity

clinicopathological

metastasis

microsatellite

tumorigenesis

adenocarcinoma

hypermethylation

methylation-specific

neoplasia

precancerous

paraffin-embedded

intraepithelial

papillomavirus

polyphosphate

tumor-suppressor

preneoplastic

p16ink4a

normal-sized

rassf1a

fra16d

hippel-lindau

3.6.1.17

caretaker

Reaction

Synonyms

Ap3A hydrolase, Ap3Aase, covalent adenylyl enzyme, Diadenosine 5',5'''-P1,P3-triphosphate hydrolase, diadenosine 5,5-P1,P3-triphosphatase, diadenosine triphosphatase, dinucleoside 5',5'''-P1,P3-triphosphate hydrolase, dinucleoside triphosphatase, dinucleoside-triphosphatase, dinucleosidetriphosphatase, Fhit, Fhit protein, FHIT protein/dinucleoside triphosphatase, fragile histidine triad, Fragile histidine triad protein, fragile HIT protein, HIT-45 protein, HIT45, tumour suppressor Fhit protein

ECTree

3 Hydrolases

3.6 Acting on acid anhydrides

3.6.1 In phosphorus-containing anhydrides

3.6.1.29 bis(5'-adenosyl)-triphosphatase

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Results	in table
2697	AA Sequence
1	CAS Registry Number
10	Cloned(Commentary)
2492	Disease/ Diagnostics
1	Expression
3	General Information
2	IC50 Value
40	Inhibitors
11	Ki Value [mM]
43	KM Value [mM]
10	Localization
34	Metals/Ions
12	Molecular Weight [Da]
40	Natural Substrates/ Products (Substrates)
48	Organism
2	Pathway
11	PDB ID
14	pH Optimum
2	pH Range
3	Posttranslational Modification
5	Protein Variants
11	Purification (Commentary)
3	Reaction
2	Reaction Type
39	Reference
52	Source Tissue
18	Specific Activity [micromol/min/mg]
2	Storage Stability
162	Substrates and Products (Substrate)
7	Subunits
50	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
1	Temperature Range [°C]
12	Turnover Number [1/s]

Purification

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Purification on EC 3.6.1.29 - bis(5'-adenosyl)-triphosphatase

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4 entries

co-expression of Fhit with the elk tyrosine kinase in Escherichia coli strain TBK1 by ion exchange chromatography, gel filtration, and another step of ion exchange chromatography

Homo sapiens

P49789

667667

native enzyme from blood platelets and leukocytes, 19000fold, by anion exchange chromatography and N6-5'-AMP affinity chromatography to homogeneity

Homo sapiens

667847

native enzyme from brain cytosolic fraction by ammonium sulfate fractionation, anion exchange chromatography, gel filtration, and N6-5'-AMP affinity chromatography to homogeneity

Rattus norvegicus

667847

Ni-NTA agarose column chromatography

partially