3.6.1.29: bis(5'-adenosyl)-triphosphatase

This is an abbreviated version!
For detailed information about bis(5'-adenosyl)-triphosphatase, go to the full flat file.

Reaction

Synonyms

Ap3A hydrolase, Ap3Aase, covalent adenylyl enzyme, Diadenosine 5',5'''-P1,P3-triphosphate hydrolase, diadenosine 5,5-P1,P3-triphosphatase, diadenosine triphosphatase, dinucleoside 5',5'''-P1,P3-triphosphate hydrolase, dinucleoside triphosphatase, dinucleoside-triphosphatase, dinucleosidetriphosphatase, Fhit, Fhit protein, FHIT protein/dinucleoside triphosphatase, fragile histidine triad, Fragile histidine triad protein, fragile HIT protein, HIT-45 protein, HIT45, tumour suppressor Fhit protein

ECTree

     3 Hydrolases

         3.6 Acting on acid anhydrides

             3.6.1 In phosphorus-containing anhydrides

                3.6.1.29 bis(5'-adenosyl)-triphosphatase

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Results	in table
2697	AA Sequence
1	CAS Registry Number
10	Cloned(Commentary)
2492	Disease/ Diagnostics
1	Expression
3	General Information
2	IC50 Value
40	Inhibitors
11	Ki Value [mM]
43	KM Value [mM]
10	Localization
34	Metals/Ions
12	Molecular Weight [Da]
40	Natural Substrates/ Products (Substrates)
48	Organism
2	Pathway
11	PDB ID
14	pH Optimum
2	pH Range
3	Posttranslational Modification
5	Protein Variants
11	Purification (Commentary)
3	Reaction
2	Reaction Type
39	Reference
52	Source Tissue
18	Specific Activity [micromol/min/mg]
2	Storage Stability
162	Substrates and Products (Substrate)
7	Subunits
50	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
1	Temperature Range [°C]
12	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 3.6.1.29 - bis(5'-adenosyl)-triphosphatase

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IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.002

suramin

Homo sapiens

-

strong, competitive inhibition, IC50: 0.002 mM

667847

0.02

Zn2+

Homo sapiens

-

IC50: 0.02 mM

667847