3.5.3.1: arginase
This is an abbreviated version!
For detailed information about arginase, go to the full flat file.
Word Map on EC 3.5.3.1
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3.5.3.1
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endothelial
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tnf
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polyamines
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myeloid-derived
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necrosis
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myeloid
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monocyte
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arterial
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lps
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lipopolysaccharide
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peritoneal
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l-ornithine
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mdscs
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pulmonary
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microglia
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ammonia
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t-cells
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argininosuccinate
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airway
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leishmania
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hypertension
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asthma
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putrescine
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immunotherapy
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marrow-derived
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tumor-associated
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leishmaniasis
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transcarbamylase
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vasodilation
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neuroinflammation
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l-citrulline
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dimethylarginine
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interleukin-10
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tregs
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l-name
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endothelium-dependent
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urease
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agmatine
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m2-like
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hyperammonemia
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no-dependent
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amazonensis
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erectile
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no-synthase
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medicine
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dimethylaminohydrolase
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ng-monomethyl-l-arginine
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bmdms
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carbamoylphosphate
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il-4-induced
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analysis
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synthesis
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pharmacology
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food industry
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drug development
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nutrition
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phosphodiesterase-5
- 3.5.3.1
- endothelial
- tnf
- polyamines
-
myeloid-derived
- necrosis
- myeloid
- monocyte
- arterial
- lps
- lipopolysaccharide
- peritoneal
- l-ornithine
-
mdscs
- pulmonary
- microglia
- ammonia
- t-cells
- argininosuccinate
- airway
- leishmania
- hypertension
- asthma
- putrescine
-
immunotherapy
-
marrow-derived
-
tumor-associated
- leishmaniasis
-
transcarbamylase
-
vasodilation
-
neuroinflammation
- l-citrulline
- dimethylarginine
- interleukin-10
-
tregs
-
l-name
-
endothelium-dependent
- urease
- agmatine
-
m2-like
- hyperammonemia
-
no-dependent
- amazonensis
-
erectile
- no-synthase
- medicine
-
dimethylaminohydrolase
- ng-monomethyl-l-arginine
-
bmdms
- carbamoylphosphate
-
il-4-induced
- analysis
- synthesis
- pharmacology
- food industry
- drug development
- nutrition
- phosphodiesterase-5
Reaction
Synonyms
ARG, Arg I, Arg II, ARG1, ARG2, ARGAH1, ARGAH2, ArgI, arginase, arginase 1, arginase 1a, arginase 1b, arginase 2a, arginase 2b, arginase I, arginase II, arginase type I, arginase-1, arginase-2, arginase1, arginine amidinase, arginine amidohydrolase-1, arginine amidohydrolase-2, arginine transamidinase, canavanase, human arginase type I, Kidney-type arginase, L-arginase, L-arginine amidino hydrolase, L-arginine amidinohydrolase, L-arginine amidohydrolase, L-arginine ureahydrolase, Liver-type arginase, mitochondrial arginase, More, Non-hepatic arginase, PMN arginase, recombinant human arginase I, rhArg-PEG, rhArg1, RocF, serum arginase, SmARG, tissue arginase, type II arginase
ECTree
3.5.3.1 arginaseAdvanced search results
results (
results (IC50 Value
IC50 Value on EC 3.5.3.1 - arginase
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IC50 VALUE [mM] 
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.0017
(DL)-2-amino-6-borono-2-[1-(3,4-dichlorobenzyl)piperidin-4-yl]-hexanoic acid
Leishmania mexicana
pH 8.0, 21°C
0.0021
(S)-2-amino-6-borono-2-[2-(piperidin-1-yl)ethyl]hexanoic acid
Leishmania mexicana
pH 8.0, 21°C
0.0165
2-(5-methyl-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)hydrazinecarbothioamide
Leishmania amazonensis
at pH 9.5 and 37°C
0.0045
2-amino-6-borono-2-butylhexanoic acid
Homo sapiens
arginase II, at pH 7.4 and 37°C
20
N-acetyl-5-hydroxytryptamine
Bos taurus
-
IC50 above 20 mM, in the presence of 0.5 mM MnCl2, at 37°C
0.00135
2-(aminomethyl)-6-borononorleucine
Homo sapiens
arginase II, at pH 7.4 and 37°C
0.00207
2-(aminomethyl)-6-borononorleucine
Homo sapiens
arginase I, at pH 7.4 and 37°C
0.00022
2-(S)-amino-6-boronohexanoic acid
Bos taurus
-
pH 9.5, 25°C, supramolecular tandem assay method
0.00326
2-[(benzylamino)methyl]-6-borononorleucine
Homo sapiens
arginase I, at pH 7.4 and 37°C
0.00598
2-[(benzylamino)methyl]-6-borononorleucine
Homo sapiens
arginase II, at pH 7.4 and 37°C
0.019
6-borono-2-(2-hydroxyethyl)norleucine
Homo sapiens
arginase I, at pH 7.4 and 37°C
0.057
6-borono-2-(2-hydroxyethyl)norleucine
Homo sapiens
arginase II, at pH 7.4 and 37°C
0.00512
6-borono-2-(3-methoxypropyl)norleucine
Homo sapiens
arginase I, at pH 7.4 and 37°C
0.00644
6-borono-2-(3-methoxypropyl)norleucine
Homo sapiens
arginase II, at pH 7.4 and 37°C
0.00225
6-borono-2-(hydroxymethyl)norleucine
Homo sapiens
arginase I, at pH 7.4 and 37°C
0.00428
6-borono-2-(hydroxymethyl)norleucine
Homo sapiens
arginase II, at pH 7.4 and 37°C
0.00037
6-borono-2-[2-(4-hydroxypiperidin-1-yl)ethyl]norleucine
Homo sapiens
arginase I, at pH 7.4 and 37°C
0.00098
6-borono-2-[2-(4-hydroxypiperidin-1-yl)ethyl]norleucine
Homo sapiens
arginase II, at pH 7.4 and 37°C
0.00052
6-borono-2-[2-(diethylamino)ethyl]norleucine
Homo sapiens
arginase I, at pH 7.4 and 37°C
0.000934
6-borono-2-[2-(diethylamino)ethyl]norleucine
Homo sapiens
arginase II, at pH 7.4 and 37°C
0.00402
6-borono-2-[2-(morpholin-4-yl)ethyl]norleucine
Homo sapiens
arginase II, at pH 7.4 and 37°C
0.00538
6-borono-2-[2-(morpholin-4-yl)ethyl]norleucine
Homo sapiens
arginase I, at pH 7.4 and 37°C
0.00032
6-borono-2-[2-(pyrrolidin-1-yl)ethyl]norleucine
Homo sapiens
arginase I, at pH 7.4 and 37°C
0.00062
6-borono-2-[2-(pyrrolidin-1-yl)ethyl]norleucine
Homo sapiens
arginase II, at pH 7.4 and 37°C
0.0219
caffeic acid
Leishmania infantum
pH 9.5, 37°C, activity in intracellular amastigote
0.287
catechin
Leishmania infantum
pH 9.5, 37°C, activity in intracellular amastigote
2.52
homoarginine
Homo sapiens
arginase 2, pH and temperature not specified in the publication
8.14
homoarginine
Homo sapiens
arginase 1, pH and temperature not specified in the publication
20
imidazole-3-lactate
Mus musculus
-
IC50 above 20 mM, in the presence of 0.5 mM MnCl2, at 37°C
20
imidazole-3-lactate
Bos taurus
-
IC50 above 20 mM, in the presence of 0.5 mM MnCl2, at 37°C
0.88
lysine
Homo sapiens
arginase 2, pH and temperature not specified in the publication
3.64
lysine
Homo sapiens
arginase 1, pH and temperature not specified in the publication
0.0079
rosmarinic acid
Leishmania infantum
pH 9.5, 37°C, activity in intracellular amastigote
0.0037
S-(2-boronoethyl)-L-cysteine
Bos taurus
-
pH 9.5, 25°C, supramolecular tandem assay method
