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highest expression in 7 week old adult
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Capra capra
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intracellular
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Vigna catjang
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low expression
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endothelial cells isolated from umbilical veins
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type I, postweaning mammals
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carcinoma tissue, increased arginase activity in various malignancies. In the event of carcinoma of the gallbladder the enzyme activity is significantly higher in comparison with cholecystitis
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HBsAg-positive HCC, HB-8064, liver cancer cell line
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macrophage cell, infection with Mycobacterium bovis strain AS-1 lacking an arginine permease. AS-1 infection enhances enzyme activity in resting J774.1 cells. Intracellular growth of AS-1 is enhanced by inhibition of enzyme and of ornithine decarboxylase using L-norvaline and difluoromethylornithine treatment
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type I
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very low expression
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significant decrease of enzyme activity during 7th-21st day of gestation, significant increase in enzyme activity at term gestation, day 22. Gestational changes in enzyme activity negatively correlate with those in cyclic GMP production and positively correlate with those in endogenous NO synthase inhibitors and endothelin-1 contents. Enhanced enzyme activity at term gestation may be implicated in increasing myometrial contractions mediated by increase in endothelin-1
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type II
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placental villi, isoform arginase-I is observed only in cytophoblasts, arginase-II in both cytophoblasts and synciotrophoblasts. Both isoforms are expressed in the first trimester and at term, enzyme activity is greater in the first trimester than at term
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for ARGAH1, but not ARGAH2
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arginase II
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S180 cells
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highest expression in 3 h old schistosomulum
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very low expression
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tissues grouped based on their expression as follows, from lowest to highest: 1. intestine; 2. adipose tissue, spleen, blood, head kidney, scales and tail fin; 3. adipose fin, brain, heart, gonad, muscle and thymus; 4. skin; 5. gills and liver; 6. posterior kidney
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mucosal layer of uterine horn, high enzyme activiy
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mucosal layer of vestibula, high enzyme activiy
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tissues grouped based on their expression as follows, from lowest to highest: 1. intestine; 2. adipose tissue, spleen, blood, head kidney, scales and tail fin; 3. adipose fin, brain, heart, gonad, muscle and thymus; 4. skin; 5. gills and liver; 6. posterior kidney
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. intestine and tail fin; 3. adipose tissue, spleen, gills and scales; 4. adipose fin, skin, blood, posterior kidney, gonad, head kidney and thymus; 5. heart; 6. brain and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. tail fin; 3. adipose tissue, intestine, posterior kidney, head kidney, heart and skin; 4. blood, gonad, scales, gills, spleen, brain, thymus; 5. adipose fin and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. tail fin, intestine and scales; 2. adipose tissue, spleen and head kidney; 3. adipose fin and posterior kidney; 4. blood, muscle and thymus; 5. gills; 6. brain, skin, heart, gonad and liver
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intact aorta
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coronary arteriole
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coronary arteriole, enzyme activity increases twofold with hypertension. Inhibition of enzyme activity by Nomega-hydroxy-nor-L-arginine or incubation with L-arginine partially restores NO release and dilation to adenosine in hypertrophic vessels
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tissues grouped based on their expression as follows, from lowest to highest: 1. intestine; 2. adipose tissue, spleen, blood, head kidney, scales and tail fin; 3. adipose fin, brain, heart, gonad, muscle and thymus; 4. skin; 5. gills and liver; 6. posterior kidney
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. intestine and tail fin; 3. adipose tissue, spleen, gills and scales; 4. adipose fin, skin, blood, posterior kidney, gonad, head kidney and thymus; 5. heart; 6. brain and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. tail fin; 3. adipose tissue, intestine, posterior kidney, head kidney, heart and skin; 4. blood, gonad, scales, gills, spleen, brain, thymus; 5. adipose fin and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. tail fin, intestine and scales; 2. adipose tissue, spleen and head kidney; 3. adipose fin and posterior kidney; 4. blood, muscle and thymus; 5. gills; 6. brain, skin, heart, gonad and liver
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tissues grouped based on their expression as follows, from lowest to highest: 1. intestine; 2. adipose tissue, spleen, blood, head kidney, scales and tail fin; 3. adipose fin, brain, heart, gonad, muscle and thymus; 4. skin; 5. gills and liver; 6. posterior kidney
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. intestine and tail fin; 3. adipose tissue, spleen, gills and scales; 4. adipose fin, skin, blood, posterior kidney, gonad, head kidney and thymus; 5. heart; 6. brain and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. tail fin; 3. adipose tissue, intestine, posterior kidney, head kidney, heart and skin; 4. blood, gonad, scales, gills, spleen, brain, thymus; 5. adipose fin and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. tail fin, intestine and scales; 2. adipose tissue, spleen and head kidney; 3. adipose fin and posterior kidney; 4. blood, muscle and thymus; 5. gills; 6. brain, skin, heart, gonad and liver
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smooth muscle
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smooth muscle
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type I
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sickle erythrocyte
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tissues grouped based on their expression as follows, from lowest to highest: 1. intestine; 2. adipose tissue, spleen, blood, head kidney, scales and tail fin; 3. adipose fin, brain, heart, gonad, muscle and thymus; 4. skin; 5. gills and liver; 6. posterior kidney
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. intestine and tail fin; 3. adipose tissue, spleen, gills and scales; 4. adipose fin, skin, blood, posterior kidney, gonad, head kidney and thymus; 5. heart; 6. brain and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. tail fin; 3. adipose tissue, intestine, posterior kidney, head kidney, heart and skin; 4. blood, gonad, scales, gills, spleen, brain, thymus; 5. adipose fin and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. tail fin, intestine and scales; 2. adipose tissue, spleen and head kidney; 3. adipose fin and posterior kidney; 4. blood, muscle and thymus; 5. gills; 6. brain, skin, heart, gonad and liver
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tissues grouped based on their expression as follows, from lowest to highest: 1. intestine; 2. adipose tissue, spleen, blood, head kidney, scales and tail fin; 3. adipose fin, brain, heart, gonad, muscle and thymus; 4. skin; 5. gills and liver; 6. posterior kidney
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. intestine and tail fin; 3. adipose tissue, spleen, gills and scales; 4. adipose fin, skin, blood, posterior kidney, gonad, head kidney and thymus; 5. heart; 6. brain and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. tail fin; 3. adipose tissue, intestine, posterior kidney, head kidney, heart and skin; 4. blood, gonad, scales, gills, spleen, brain, thymus; 5. adipose fin and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. tail fin, intestine and scales; 2. adipose tissue, spleen and head kidney; 3. adipose fin and posterior kidney; 4. blood, muscle and thymus; 5. gills; 6. brain, skin, heart, gonad and liver
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tissues grouped based on their expression as follows, from lowest to highest: 1. intestine; 2. adipose tissue, spleen, blood, head kidney, scales and tail fin; 3. adipose fin, brain, heart, gonad, muscle and thymus; 4. skin; 5. gills and liver; 6. posterior kidney
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. intestine and tail fin; 3. adipose tissue, spleen, gills and scales; 4. adipose fin, skin, blood, posterior kidney, gonad, head kidney and thymus; 5. heart; 6. brain and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. tail fin, intestine and scales; 2. adipose tissue, spleen and head kidney; 3. adipose fin and posterior kidney; 4. blood, muscle and thymus; 5. gills; 6. brain, skin, heart, gonad and liver
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tissues grouped based on their expression as follows, from lowest to highest: 1. intestine; 2. adipose tissue, spleen, blood, head kidney, scales and tail fin; 3. adipose fin, brain, heart, gonad, muscle and thymus; 4. skin; 5. gills and liver; 6. posterior kidney
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. tail fin; 3. adipose tissue, intestine, posterior kidney, head kidney, heart and skin; 4. blood, gonad, scales, gills, spleen, brain, thymus; 5. adipose fin and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. tail fin, intestine and scales; 2. adipose tissue, spleen and head kidney; 3. adipose fin and posterior kidney; 4. blood, muscle and thymus; 5. gills; 6. brain, skin, heart, gonad and liver
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normal and hypertrophied feline myocardium, both isoforms arginase-I and arginase-II in crude myocardial homogenate. Arginase-I is downregulated in left ventricular hypertrophy
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tissues grouped based on their expression as follows, from lowest to highest: 1. intestine; 2. adipose tissue, spleen, blood, head kidney, scales and tail fin; 3. adipose fin, brain, heart, gonad, muscle and thymus; 4. skin; 5. gills and liver; 6. posterior kidney
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. intestine and tail fin; 3. adipose tissue, spleen, gills and scales; 4. adipose fin, skin, blood, posterior kidney, gonad, head kidney and thymus; 5. heart; 6. brain and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. tail fin; 3. adipose tissue, intestine, posterior kidney, head kidney, heart and skin; 4. blood, gonad, scales, gills, spleen, brain, thymus; 5. adipose fin and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. tail fin, intestine and scales; 2. adipose tissue, spleen and head kidney; 3. adipose fin and posterior kidney; 4. blood, muscle and thymus; 5. gills; 6. brain, skin, heart, gonad and liver
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heart homogenate
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HBV-negative hepatoblastoma, HB-8065, liver cancer cell line
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type I
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24h culture, both enzyme and NOS-2 activity depend strongly on extracellular L-arginine concentrations. Competing for L-arginine influx by addition of L-lysine results in 60-70% inhibition of enzyme. Addition of enzyme inhibitor L-valine to cells leads to 80-90% decrease in enzyme activity and 25% increase in NOS-2 activity
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arginase activity in hepatoma cell is nearly 5fold and 15fold lower than in cirrhotic and normal livers, respectively. The amount of arginase I, as well as the expression of arginase I-mRNA are lower in hepatoma cell, in comparison with normal liver, and those of arginase II are significantly higher
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arginase activity in hepatoma cell is nearly 5fold and 15fold lower than in cirrhotic and normal livers, respectively. The amount of arginase I, as well as the expression of arginase I-mRNA are lower in HCC, in comparison with normal liver, and those of arginase II are significantly higher
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HCC
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intesintal lumen
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tissues grouped based on their expression as follows, from lowest to highest: 1. intestine; 2. adipose tissue, spleen, blood, head kidney, scales and tail fin; 3. adipose fin, brain, heart, gonad, muscle and thymus; 4. skin; 5. gills and liver; 6. posterior kidney
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. intestine and tail fin; 3. adipose tissue, spleen, gills and scales; 4. adipose fin, skin, blood, posterior kidney, gonad, head kidney and thymus; 5. heart; 6. brain and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. tail fin; 3. adipose tissue, intestine, posterior kidney, head kidney, heart and skin; 4. blood, gonad, scales, gills, spleen, brain, thymus; 5. adipose fin and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. tail fin, intestine and scales; 2. adipose tissue, spleen and head kidney; 3. adipose fin and posterior kidney; 4. blood, muscle and thymus; 5. gills; 6. brain, skin, heart, gonad and liver
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mid kidney, basal enzyme expression
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arginase II
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tissues grouped based on their expression as follows, from lowest to highest: 1. intestine; 2. adipose tissue, spleen, blood, head kidney, scales and tail fin; 3. adipose fin, brain, heart, gonad, muscle and thymus; 4. skin; 5. gills and liver; 6. posterior kidney. Arginase 1a is often higher than arginase 1b, with highest expression seen in the posterior kidney
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. intestine and tail fin; 3. adipose tissue, spleen, gills and scales; 4. adipose fin, skin, blood, posterior kidney, gonad, head kidney and thymus; 5. heart; 6. brain and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. tail fin; 3. adipose tissue, intestine, posterior kidney, head kidney, heart and skin; 4. blood, gonad, scales, gills, spleen, brain, thymus; 5. adipose fin and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. tail fin, intestine and scales; 2. adipose tissue, spleen and head kidney; 3. adipose fin and posterior kidney; 4. blood, muscle and thymus; 5. gills; 6. brain, skin, heart, gonad and liver
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isozyme II
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induction of isoform LeARG2 upon wounding and treatment with jasmonic acid
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172099, 172116, 172133, 668256, 668975, 670050, 670051, 670930, 684384, 688021, 696006, 696016, 704175 brenda
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highest expression of all organs examined
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arginase I
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tissues grouped based on their expression as follows, from lowest to highest: 1. intestine; 2. adipose tissue, spleen, blood, head kidney, scales and tail fin; 3. adipose fin, brain, heart, gonad, muscle and thymus; 4. skin; 5. gills and liver; 6. posterior kidney
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. intestine and tail fin; 3. adipose tissue, spleen, gills and scales; 4. adipose fin, skin, blood, posterior kidney, gonad, head kidney and thymus; 5. heart; 6. brain and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. tail fin; 3. adipose tissue, intestine, posterior kidney, head kidney, heart and skin; 4. blood, gonad, scales, gills, spleen, brain, thymus; 5. adipose fin and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. tail fin, intestine and scales; 2. adipose tissue, spleen and head kidney; 3. adipose fin and posterior kidney; 4. blood, muscle and thymus; 5. gills; 6. brain, skin, heart, gonad and liver
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172101, 172111, 172116, 172124, 654949, 655995, 656381, 656441, 667319, 669653, 697334, 711094 brenda
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highest enzymic activity
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isozyme I
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airways
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isolated microdissected airway preparations. Arginase II is constitutively expressed in the airways of normal mice, whereas arginase I is undetectable in normal airways, while its expression is increased in airways of mice exposed to ovalbumin
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developmental changes in arginase expression and activity in the lung
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cultured head-kidney derived macrophages, significant enzyme activity, inhibitable by Nomega-hydroxy-L-arginine and induced by dibutyryl cyclic adenosine
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cultured head-kidney derived macrophages, significant enzyme activity, inhibitable by Nomega-hydroxy-L-arginine, not inducible by dibutyryl cyclic adenosine
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alveolar macrophage
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type I
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alveolar macrophage
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tissues grouped based on their expression as follows, from lowest to highest: 1. intestine; 2. adipose tissue, spleen, blood, head kidney, scales and tail fin; 3. adipose fin, brain, heart, gonad, muscle and thymus; 4. skin; 5. gills and liver; 6. posterior kidney
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. intestine and tail fin; 3. adipose tissue, spleen, gills and scales; 4. adipose fin, skin, blood, posterior kidney, gonad, head kidney and thymus; 5. heart; 6. brain and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. tail fin; 3. adipose tissue, intestine, posterior kidney, head kidney, heart and skin; 4. blood, gonad, scales, gills, spleen, brain, thymus; 5. adipose fin and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. tail fin, intestine and scales; 2. adipose tissue, spleen and head kidney; 3. adipose fin and posterior kidney; 4. blood, muscle and thymus; 5. gills; 6. brain, skin, heart, gonad and liver
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isolated cardiac myocyte shows only isoform arginase-I
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isolated myocyte, isoform arginase II
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submandibular, sublingual, and parotid gland
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submandibular, sublingual, and parotid gland, 3.6-7.3% of the activity in liver. In submandibluar gland, presence of both isoform arginase I and arginase II
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GUS staining of seedlings
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tissues grouped based on their expression as follows, from lowest to highest: 1. intestine; 2. adipose tissue, spleen, blood, head kidney, scales and tail fin; 3. adipose fin, brain, heart, gonad, muscle and thymus; 4. skin; 5. gills and liver; 6. posterior kidney
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. intestine and tail fin; 3. adipose tissue, spleen, gills and scales; 4. adipose fin, skin, blood, posterior kidney, gonad, head kidney and thymus; 5. heart; 6. brain and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. tail fin; 3. adipose tissue, intestine, posterior kidney, head kidney, heart and skin; 4. blood, gonad, scales, gills, spleen, brain, thymus; 5. adipose fin and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. tail fin, intestine and scales; 2. adipose tissue, spleen and head kidney; 3. adipose fin and posterior kidney; 4. blood, muscle and thymus; 5. gills; 6. brain, skin, heart, gonad and liver
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rejection of skin xenografts, but not allografts, is associated with a local high production of Th2 cytokines IL-4 and IL-10, overexpression of enzyme, strongly enhanced enzyme activity and attenuated NO generation in the graft
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of penile corpus cavernosum
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of penile corpus cavernosum
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tissues grouped based on their expression as follows, from lowest to highest: 1. intestine; 2. adipose tissue, spleen, blood, head kidney, scales and tail fin; 3. adipose fin, brain, heart, gonad, muscle and thymus; 4. skin; 5. gills and liver; 6. posterior kidney
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. intestine and tail fin; 3. adipose tissue, spleen, gills and scales; 4. adipose fin, skin, blood, posterior kidney, gonad, head kidney and thymus; 5. heart; 6. brain and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. tail fin; 3. adipose tissue, intestine, posterior kidney, head kidney, heart and skin; 4. blood, gonad, scales, gills, spleen, brain, thymus; 5. adipose fin and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. tail fin, intestine and scales; 2. adipose tissue, spleen and head kidney; 3. adipose fin and posterior kidney; 4. blood, muscle and thymus; 5. gills; 6. brain, skin, heart, gonad and liver
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tissues grouped based on their expression as follows, from lowest to highest: 1. intestine; 2. adipose tissue, spleen, blood, head kidney, scales and tail fin; 3. adipose fin, brain, heart, gonad, muscle and thymus; 4. skin; 5. gills and liver; 6. posterior kidney
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. intestine and tail fin; 3. adipose tissue, spleen, gills and scales; 4. adipose fin, skin, blood, posterior kidney, gonad, head kidney and thymus; 5. heart; 6. brain and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. liver; 2. tail fin; 3. adipose tissue, intestine, posterior kidney, head kidney, heart and skin; 4. blood, gonad, scales, gills, spleen, brain, thymus; 5. adipose fin and muscle
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tissues grouped based on their expression as follows, from lowest to highest: 1. tail fin, intestine and scales; 2. adipose tissue, spleen and head kidney; 3. adipose fin and posterior kidney; 4. blood, muscle and thymus; 5. gills; 6. brain, skin, heart, gonad and liver
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additional information
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enzyme is present at different levels in all parts of cattle reproductive system
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additional information
enzyme found in all organs examined
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additional information
enzyme found in all organs examined
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additional information
enzyme found in all organs examined
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additional information
enzyme found in all organs examined
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additional information
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enzyme found in all organs examined
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additional information
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extrahepatic
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additional information
nonhepatic tissue
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additional information
nonhepatic tissue
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additional information
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preparation of all and tissue extract
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additional information
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type II in mitochondria-containing extrahepatic cells
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additional information
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extrahepatic
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additional information
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rejection of skin xenografts, but not allografts, is associated with a local high production of Th2 cytokines IL-4 and IL-10, overexpression of enzyme, strongly enhanced enzyme activity and attenuated NO generation in the graft
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additional information
arginase II is regulated developmentally, and both expression and activity are maximal during fetal life
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additional information
arginase II is regulated developmentally, and both expression and activity are maximal during fetal life
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additional information
highest levels of enzyme activity in reproductive tissues
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additional information
highest levels of enzyme activity in reproductive tissues
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additional information
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highest levels of enzyme activity in reproductive tissues
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