3.5.3.1: arginase
This is an abbreviated version!
For detailed information about arginase, go to the full flat file.
Word Map on EC 3.5.3.1
-
3.5.3.1
-
endothelial
-
tnf
-
polyamines
-
myeloid-derived
-
necrosis
-
myeloid
-
monocyte
-
arterial
-
lps
-
lipopolysaccharide
-
peritoneal
-
l-ornithine
-
mdscs
-
pulmonary
-
microglia
-
ammonia
-
t-cells
-
argininosuccinate
-
airway
-
leishmania
-
hypertension
-
asthma
-
putrescine
-
immunotherapy
-
marrow-derived
-
tumor-associated
-
leishmaniasis
-
transcarbamylase
-
vasodilation
-
neuroinflammation
-
l-citrulline
-
dimethylarginine
-
interleukin-10
-
tregs
-
l-name
-
endothelium-dependent
-
urease
-
agmatine
-
m2-like
-
hyperammonemia
-
no-dependent
-
amazonensis
-
erectile
-
no-synthase
-
medicine
-
dimethylaminohydrolase
-
ng-monomethyl-l-arginine
-
bmdms
-
carbamoylphosphate
-
il-4-induced
-
analysis
-
synthesis
-
pharmacology
-
food industry
-
drug development
-
nutrition
-
phosphodiesterase-5
- 3.5.3.1
- endothelial
- tnf
- polyamines
-
myeloid-derived
- necrosis
- myeloid
- monocyte
- arterial
- lps
- lipopolysaccharide
- peritoneal
- l-ornithine
-
mdscs
- pulmonary
- microglia
- ammonia
- t-cells
- argininosuccinate
- airway
- leishmania
- hypertension
- asthma
- putrescine
-
immunotherapy
-
marrow-derived
-
tumor-associated
- leishmaniasis
-
transcarbamylase
-
vasodilation
-
neuroinflammation
- l-citrulline
- dimethylarginine
- interleukin-10
-
tregs
-
l-name
-
endothelium-dependent
- urease
- agmatine
-
m2-like
- hyperammonemia
-
no-dependent
- amazonensis
-
erectile
- no-synthase
- medicine
-
dimethylaminohydrolase
- ng-monomethyl-l-arginine
-
bmdms
- carbamoylphosphate
-
il-4-induced
- analysis
- synthesis
- pharmacology
- food industry
- drug development
- nutrition
- phosphodiesterase-5
Reaction
Synonyms
ARG, Arg I, Arg II, ARG1, ARG2, ARGAH1, ARGAH2, ArgI, arginase, arginase 1, arginase 1a, arginase 1b, arginase 2a, arginase 2b, arginase I, arginase II, arginase type I, arginase-1, arginase-2, arginase1, arginine amidinase, arginine amidohydrolase-1, arginine amidohydrolase-2, arginine transamidinase, canavanase, human arginase type I, Kidney-type arginase, L-arginase, L-arginine amidino hydrolase, L-arginine amidinohydrolase, L-arginine amidohydrolase, L-arginine ureahydrolase, Liver-type arginase, mitochondrial arginase, More, Non-hepatic arginase, PMN arginase, recombinant human arginase I, rhArg-PEG, rhArg1, RocF, serum arginase, SmARG, tissue arginase, type II arginase
ECTree
3.5.3.1 arginaseAdvanced search results
results (
results (Activating Compound
Activating Compound on EC 3.5.3.1 - arginase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
ACTIVATING COMPOUND 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
1-amino-6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid methyl ester
-
activity is enhanced in the presence of the dihydropyrimidine derivative
cysteine
-
effect of cysteine on arginase activity, effect of increasing concentrations of cysteine alone or in combination with iron (II) sulfate on the enhancement of arginase activity in human sickle erythrocytes or purified arginase-1 from Bos taurus liver
dexamethasone
-
augments arginase activity in Actinobacillus actinomycetemcomitans-lipopolysaccharide-stimulated cells
FeSO4
-
effect of cysteine on arginase activity, effect of increasing concentrations of cysteine alone or in combination with iron (II) sulfate on the enhancement of arginase activity in human sickle erythrocytes or purified arginase-1 from Bos taurus liver
hydralazine
-
treatment with 20 mg/kg/day hydralazine for 5 weeks causes increased arginase activity in hypertensive rats
IL-4
-
interleukin IL-4, up to 16-fold stimulation of enzyme activity in RAW-264.7 cell, in combinantion with rolipram additional activation. No stimulation of enzyme in alveolar macrophages by IL-4 alone, but increase of stimulation by forskolin and 3-isobutyl-1-methylxanthine, IBMX, in presence of IL-4
-
interleukin-4
-
augments arginase activity in Actinobacillus actinomycetemcomitans-lipopolysaccharide-stimulated cells
-
low-density lipoprotein
-
ArgI expression is potently induced by both oxidized and acetylated low-density lipoprotein in macrophages, this effect is mediated by peroxisome proliferator-activated receptors
-
TGF-beta
-
transforming growth factor, up to 5-fold stimulation, further stimulation in combination with rolipram
-
thrombin receptor antagonist peptide
-
endothelial cell exposition to 10 U/ml thrombin receptor antagonist peptide for 4 h leads to increased arginase activity
-
L-arginine
-
strong substrate activation of the kidney enzyme at concentrations above 4 mM
L-arginine
the enzyme is kinetically cooperative and the commonly detected hyperbolic behavior results from binding of L-arginine as a typical allosteric activator
lipopolysaccharide
-
lipopolysaccharide from Actinobacillus actinomycetemcomitans or Escherichia coli
lipopolysaccharide
-
0.001 mg/ml cause a 2fold increase in arginase activity and a marked increase in mRNA encoding arginase I
thrombin
-
endothelial cell exposition to 10 U/ml thrombin for 4 h leads to 1.6fold increased arginase activity
-
additional information
-
treatment with methyl jasmonate. ARGAH1 expression is lower in argah1-1 mutants compared to either wild-type or argah2-1 plants and does not increase in any genotype following methyl jasmonate treatment
-
additional information
-
rolipram increases stimulation by interleukin IL-4 and transforming growth factor beta
-
additional information
-
interferon-gamma does not augment arginase activity in Actinobacillus actinomycetemcomitans lipopolysaccharide-stimulated cells
-
additional information
-
expression of arginase I strongly correlated with the presence of lung inflammation, as quantified by differential cell counts in lung lavage, suggesting that most, or all, of the arginase I in lungs of mice exposed to ovalbumin is present in the inflammatory cells rather than in the airway epithelium
-
